[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pathological-fracture-right-femur\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pathological-fracture-right-femur":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100513745","short-versus-long-intramedullary-nails-in-the-treatment-of-proximal-femur-metastasis-100513745",false,"NCT05969470","Short Versus Long Intramedullary Nails in the Treatment of Proximal Femur Metastasis.","Compare the Efficacy of Long-nailed and Short-nailed Fixation for Proximal Femur Metastasis - a Non-inferior Randomized Controlled Trial","Inclusion Criteria:\n\n* Femur (impending) pathological fracture that is suitable for intramedullary nail fixation as determined by the physician\n* Patient is willing to participate in this clinical trial and cooperate with follow-up\n\nExclusion Criteria:\n\n* The patient has a more appropriate treatment alternative to single intramedullary nail fixation as determined by the multidisciplinary decision, such as,\n\n  * The metastatic lesions involved the femur head\n  * The metastatic lesions involved the pelvis\n  * The metastatic lesions compromised the greater or lesser trochanter to a certain extent that arthroplasty was indicated\n  * The metastatic lesions involved\u002Foccurred more distal than the intertrochanteric line\n* There are justified, clinically significant rationales that either long or short intramedullary nails be a more appropriate treatment during pre-operative assessment\n* The patient has imaging-confirmed distant femoral metastases before treatment\n* Patient has renal cell carcinoma or sarcoma\n* Patient is unable to cooperate with follow-up or to understand the trial protocol\n* Patient is unable to communicate in Chinese","ALL","20 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this interventional randomized controlled trial is to compare the clinical outcomes in treating extremities pathological fractures (fractures of limbs caused by metastatic tumors) or impending pathological fractures with short or long intramedullary nails. The main questions it aims to answer are:\n\n1. What is the rate of developing new distant metastasis of the operated extremities?\n2. Does treating extremities (impending) pathological fractures with long intramedullary nails have lower or similar reoperation rate than the short nails?\n3. Are there any differences when comparing the surgical-related complication, functional outcomes and life quality assessment between treating extremities (impending) pathological fractures with long or short intramedullary nails.\n\nParticipants who meet surgical indication will be randomized into either the long or short intramedullary nail group after informed consent. The patient will receive bone fixation with the corresponding prosthesis.",[26,27,28,29],"Bone Metastases","Pathological Fracture","Pathological Fracture, Left Femur","Pathological Fracture, Right Femur",[31,32,26,33],"Long Intramedullary Nails","Short Intramedullary Nails","Pathological Fracture of Femur","NOT_YET_RECRUITING","2023-08-15",{"date":37,"type":38},"2023-08-18","ACTUAL",{"date":40,"type":20},"2023-08-31",{"date":42,"type":20},"2027-06",{"name":44,"class":45},"National Taiwan University Hospital","OTHER"]