[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pediatric-bladder-stones\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pediatric-bladder-stones":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100640160","vacuum-assisted-mini-percutaneous-versus-transurethral-cystolithotripsy-in-pediatric-bladder-stones-100640160",false,"NCT07614880","Vacuum-Assisted Mini-Percutaneous Versus Transurethral Cystolithotripsy in Pediatric Bladder Stones","Vacuum-Assisted Mini-Percutaneous Cystolithotomy Versus Transurethral Cystolithotripsy in Pediatric Bladder Stones: A Prospective Randomized Study","VAMPCL-Ped","Inclusion Criteria:\n\n* Children aged 2 to 14 years.\n* Diagnosis of bladder stone or stones measuring 10-30 mm in maximum cumulative diameter, confirmed by ultrasound.\n* Normal upper urinary tract.\n* Fit for general anesthesia.\n* Written informed consent obtained from parents or legal guardians.\n\nExclusion Criteria:\n\n* Known urethral stricture or posterior urethral valves.\n* Active urinary tract infection at the time of surgery.\n* Coagulopathy or uncorrected bleeding disorder.\n* Previous open bladder surgery.\n* Any anatomical or clinical condition that, in the investigator's judgment, precludes safe endoscopic or percutaneous cystolithotripsy.","ALL","2 Years","14 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","This prospective randomized pilot study will compare vacuum-assisted mini-percutaneous cystolithotripsy with standard transurethral cystolithotripsy for the treatment of bladder stones in children. Forty children aged 2 to 14 years with bladder stone(s) measuring 10 -30 mm will be randomly assigned to one of two surgical approaches. The vacuum-assisted mini-percutaneous group will undergo suprapubic percutaneous access using a mini sheath with suction-assisted fragment evacuation, while the transurethral group will undergo standard transurethral cystolithotripsy. The primary outcome will be total operative time. Secondary outcomes will include stone-free rate ,lithotripsy time and fragment clearance time, urethral mucosal injury, postoperative hematuria, fever, urinary tract infection, sepsis, urinary retention, urinary leakage from the suprapubic tract, catheterization time, hospital stay, postoperative pain, analgesic requirement, need for auxiliary procedures or conversion, and recurrence or urethral stricture-related symptoms during follow-up.",[28,29,30],"Pediatric Bladder Stones","Bladder Calculi","Pediatric Urolithiasis",[32,33,34,35],"Pediatric bladder stones","Mini-percutaneous cystolithotripsy","Vacuum-assisted cystolithotripsy","Ho:YAG laser lithotripsy","RECRUITING","2026-05-28",{"date":39,"type":40},"2026-06-01","ACTUAL",{"date":42,"type":40},"2026-03-04",{"date":44,"type":22},"2028-03",{"name":46,"class":47},"Beni-Suef University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":48},"100640178","dusting-vs-fragmentation-laser-cystolithotripsy-for-pediatric-bladder-stones-100640178","NCT07623980","Dusting vs Fragmentation Laser Cystolithotripsy for Pediatric Bladder Stones","Dusting Versus Fragmentation With Holmium:YAG Laser During Transurethral Cystolithotripsy in Pediatric Bladder Stones: A Prospective Randomized Trial","DUST-FRAG-PED","Inclusion Criteria:\n\n1. Children aged less than 18 years.\n2. Radiologically confirmed single bladder stone less than 3 cm.\n3. Suitable for transurethral cystolithotripsy.\n4. Fit for general anesthesia.\n5. Written informed consent from parents or legal guardians.\n\nExclusion Criteria:\n\n1. Giant bladder stones more than 3 cm.\n2. Urethral pathology preventing safe transurethral access.\n3. Major lower urinary tract anomaly or neurogenic bladder.\n4. Active untreated urinary tract infection.\n5. Coagulation disorder or contraindication to endoscopic surgery.","18 Years",{"count":59,"type":22},110,[25],"Bladder stones are a clinically relevant pediatric urological condition that may require endoscopic treatment. Transurethral Holmium:YAG laser cystolithotripsy is a minimally invasive option for selected children with bladder stones.\n\nThis prospective randomized trial will compare two Holmium:YAG laser strategies during transurethral cystolithotripsy in children with a single bladder stone less than 3 cm: dusting and fragmentation. Children will be randomized to undergo laser dusting or laser fragmentation during transurethral cystolithotripsy.\n\nThe primary outcome is total operative time. Secondary outcomes include laser time, need for active fragment extraction, endoscopic stone-free status at the end of the procedure, ultrasound-assessed stone-free status during follow-up, intraoperative complications, postoperative urinary symptoms, urinary tract infection, need for postoperative catheterization, and hospital stay.",[29,28,30],[64,65,66,67,68],"Transurethral cystolithotripsy","Dusting","Holmium:YAG laser","Fragmentation","Bladder stone surgery",{"date":70,"type":40},"2026-06-03",{"date":72,"type":40},"2026-05-06",{"date":74,"type":22},"2027-05",{"name":46,"class":47}]