[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pediatric-cataract\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pediatric-cataract":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,78,104],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100620957","myopia-progression-control-using-atropine-005-after-pediatric-cataract-surgery-and-intraocular-lens-implantation-surgery-100620957",false,"NCT07364370","Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation Surgery","Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation Surgery: A Randomized Clinical Trial","Inclusion criteria:\n\n1. Children after IOL implantation (primary or secondary)\n2. Age 1-7 years\n\nExclusion criteria:\n\n1. Eyes with post-operative media opacity hindering adequate assessment of refraction\n2. Eyes with complicated surgeries (e.g. vitreous loss, dropped lens matter requiring PPV, retinal detachment, etc)\n3. Retinal pathologies\n4. Glaucoma (congenital or secondary to surgery)\n5. Anterior or posterior segment anomalies","ALL","1 Year","7 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","Myopic shift remains a debilitating and unpredictable adverse event following pediatric cataract surgery. While research exploring peripheral myopic defocus for post-cataract surgery myopia prevention shows promising results, the use of multifocal intra-ocular lenses (IOLs) cannot be used liberally in countries with high disease burden and challenged economies due to high price and decreased availability. To date there are no studies evaluating the use of topical atropine for the management of myopic shift following pediatric cataract surgery.\n\nThe investigators aim to explore the use of 0.05% topical atropine in the prevention and management of myopic shift following pediatric cataract surgery.",[27,28,29],"Pediatric Cataract","IOL Implantation","Myopia Progression",[31,32,33,34],"pediatric cataract","iol","iol implantation","myopia","NOT_YET_RECRUITING","2026-01-15",{"date":38,"type":39},"2026-01-23","ACTUAL",{"date":41,"type":21},"2026-02",{"date":43,"type":21},"2027-12",{"name":45,"class":46},"Cairo University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":47},"100598326","five-year-visual-function-and-refractive-outcomes-after-congenital-cataract-surgery-100598326","NCT07070037","Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery","Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery: A Multicenter Observational Cohort Study","Inclusion Criteria:\n\n* Diagnosis of congenital cataract\n* Underwent cataract extraction before 1 year of age\n* Available for regular follow-up for at least 5 years postoperatively\n* Written informed consent from legal guardian\n\nExclusion Criteria:\n\n* Acquired cataract or traumatic origin\n* Associated ocular malformations (e.g., microphthalmia, coloboma)\n* Systemic syndromes affecting vision (e.g., Down syndrome)\n* History of secondary surgery affecting visual outcome","18 Years",{"count":57,"type":21},400,"OBSERVATIONAL","This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract. Key outcomes include best-corrected visual acuity, stereopsis, refractive error, and axial length growth. The study will help identify long-term trends and prognostic indicators after early cataract intervention in pediatric patients.",[61,27],"Congenital Cataract",[61,63,64,65,66,67],"Pediatric Cataract Surgery","Visual Function","Stereopsis","Amblyopia","Long-term Outcomes","RECRUITING","2025-08-15",{"date":71,"type":39},"2025-08-20",{"date":73,"type":39},"2014-01-01",{"date":75,"type":21},"2035-12-31",{"name":77,"class":46},"Jin Yang",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":16,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":89,"studyType":58,"phases":4,"briefSummary":90,"conditions":91,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":47},"100290627","shanghai-pediatric-cataract-study-100290627","NCT03063216","Shanghai Pediatric Cataract Study","Visual Outcome Evaluation and Genetic Analysis: Shanghai Pediatric Cataract Study","Inclusion Criteria:\n\n* Clinical diagnosis of pediatric cataract\n* Must be able to cooperate with the ophthalmic examination\n\nExclusion Criteria:\n\n* Clinical diagnosis of mental illness\n* Mentally disabled","2 Months","20 Years",{"count":88,"type":21},10000,"10 Years","The purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of pediatric cataract participants, including congenital and traumatic cataract. The investigators will further investigate into the various genetic and environmental factors that may contribute to the pathogenesis of pediatric cataract.",[27,61,92,93,94],"Traumatic Cataract","Visual Outcome","Genetic Anticipation","2024-09-25",{"date":97,"type":39},"2024-09-27",{"date":99,"type":39},"2009-01-01",{"date":101,"type":21},"2045-12-31",{"name":103,"class":46},"Evidence Based Cataract Study Group",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":55,"enrollmentInfo":110,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":112,"conditions":113,"keywords":114,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":47},"100475585","the-cohort-study-of-pediatric-cataract-100475585","NCT05472844","The Cohort Study of Pediatric Cataract","Inclusion Criteria:\n\n* aged \\\u003C 18 yo at the 1st visit unilateral or bilateral cataract agree to participant in this study and sign the informed consent\n\nExclusion Criteria:\n\n* adults",{"count":111,"type":21},5000,"This retrospective-prospective bidirectional cohort study aims to observe ocular parameter changes, different surgical\u002Fvision recovery strategies and postoperative adverse effects among young children with cataract. The influence on psychology and cognitive function will be taken into consideration as well.",[27],[115,116,117,118,119,120,121,122],"congenital cataract","traumatic cataract","complicated cataract","ocular structure parameters","surgical\u002Fvision recovery timing and strategies","postoperative adverse effects","psychologic and cognitive function","artificial intelligence","2022-09-26",{"date":125,"type":39},"2022-09-27",{"date":127,"type":39},"2022-08-22",{"date":129,"type":21},"2032-02-01",{"name":131,"class":46},"Zhongshan Ophthalmic Center, Sun Yat-sen University"]