[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pediatric-liver-transplantation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pediatric-liver-transplantation":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100608542","validation-of-imaging-based-liver-biomarkers-in-pediatric-patients-100608542",false,"NCT07202910","VALidation of Imaging-based Liver Biomarkers in PEDiatric Patients","Imaging-Based Biomarkers for Non-Invasive Pediatric Liver Diagnostics","VALiBi-PED","Inclusion Criteria (Study 1-main study)\n\n* all patients scheduled for a clinically liver biopsy at the Queen Silvia Children's Hospital\n* any form of suspected or confirmed liver disease\n* age between 0-18 years\n* consent by the child\u002Fparents to participate.\n* For controls: children scheduled for a renal biopsy\n* age between 0-18 years\n* consent by the child\u002Fparents to participate.\n\nExclusion Criteria:\n\n* technical limitations regarding the measurements\n* inability to fully understand the informed consent documents.",true,"ALL","25 Years",{"count":21,"type":22},550,"ESTIMATED","OBSERVATIONAL","The goal of this observational (diagnostic validation) study is to validate imaging-based biomarkers for assessing liver involvement in pediatric patients with established or suspected liver disease. The projekt involves 3 larger studies, each with specific aims specified in detailed description below.\n\nThe main study (study 1) compares imaging-based biomarkers-with liver biopsy to evaluate their correlation with histologically confirmed liver disease, including fibrosis, inflammation, and steatosis. The main question the overall project aims to answer is:\n\n• Can multiple novel imaging-based biomarkers, such as shear wave elastography (SWE), shear wave dispersion (SWD), and attenuation imaging (ATI), be used for detailed, non-invasive liver characterization in children, and if so, how should they be used?",[26,27,28,29,30],"Hepatic Disorders","Intestinal Failure-associated Liver Disease","Cystic Fibrosis Liver Disease","MAFLD","Pediatric Liver Transplantation",[32,33,34,35,28,36,37,38,39,29],"pediatric hepatic disease,","obesity and overweight","intestinal failiure associated liver disease","liver transplant disorder","Liver disease or abnormalities","pediatric liver transplant","pediatric abdominal imaging","elastography","RECRUITING","2025-09-23",{"date":43,"type":44},"2025-10-02","ACTUAL",{"date":46,"type":44},"2019-03-28",{"date":48,"type":22},"2032-12",{"name":50,"class":51},"Sahlgrenska University Hospital","OTHER"]