[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pediatric-obstructive-sleep-apnea\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pediatric-obstructive-sleep-apnea":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,76,107],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100443270","development-of-a-wearable-point-of-care-monitoring-device-for-pediatric-obstructive-sleep-apnea-100443270",false,"NCT05052216","Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea","* INCLUSION CRITERIA:\n\nIn order to be eligible to participate in this study, an individual must meet all of the following criteria:\n\n1. Male or female, aged \\>=3 and \\\u003C13 years\n2. For NORM group: Children without OSA (AHI\\\u003C2)\n3. For OSA group: Children with OSA (AHI\\>=2)\n\nEXCLUSION CRITERIA:\n\nAn individual who meets any of the following criteria will be excluded from participation in this study:\n\n1. Children \\\u003C3 years or \\>=13 years\n2. Any chronic or acute medical condition that in the opinion of the investigators will interfere with overnight sleep study acquisition.\n3. Any head injuries or physical conditions that in the opinion of the investigators would affect probe signal and contact.\n4. For NORM group: Children with AHI\\>=2\n5. For OSA group: Children with AHI\\\u003C2",true,"ALL","3 Years","12 Years",{"count":20,"type":21},120,"ESTIMATED","OBSERVATIONAL","Background:\n\nObstructive sleep apnea (OSA) occurs when the blockage of the airway causes a person to stop breathing involuntarily for 10 seconds or more throughout the night during sleep. Pediatric OSA can be especially concerning and can have long-term effects. Researchers want to see how a monitoring device called near-infrared spectroscopy (NIRS) compares with the traditional techniques used in children s sleep studies.\n\nObjective:\n\nTo learn about oxygen levels in the brain and limbs in children with and without sleep apnea using a wearable, point-of-care biosensor.\n\nEligibility:\n\nChildren aged 3-12 who have OSA and plan to receive treatment (OSA group) or who do not have OSA (NORM group).\n\nDesign:\n\nParticipants will be screened with a review of their medical records. If they have taken part in other NIH studies, that data will be reviewed as well.\n\nParticipants in the NORM group will have 1 overnight study visit. Those in the OSA group will have 2 overnight study visits.\n\nParticipants will do an overnight sleep study. They will have a physical exam and medical history. They will have a sleep study electroencephalography (EEG). For this, electrodes will be placed on their head. They will wear a gauze cap to keep the electrodes in place. Two NIRS probes made of a soft silicon will be placed on their forehead and arm. They will follow their normal bedtime routine. Their parent will stay overnight.\n\nThe OSA group will have a second study visit 2 weeks to 12 months after they start treatment for their sleep apnea. They will repeat the sleep study.",[25],"Pediatric Obstructive Sleep Apnea",[27,28,29,30],"near-infrared spectroscopy (NIRS)","tissue oxygenation","Polysomnography","Natural History","RECRUITING","2026-06-23",{"date":34,"type":35},"2026-06-24","ACTUAL",{"date":37,"type":35},"2022-08-25",{"date":39,"type":21},"2028-01-31",{"name":41,"class":42},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":15,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100638319","pediatric-obstructive-sleep-apnea-among-dental-interns-in-egyptian-universities-100638319","NCT07604831","Pediatric Obstructive Sleep Apnea Among Dental Interns in Egyptian Universities","Knowledge, Attitude, and Practice Regarding the Management of Pediatric Obstructive Sleep Apnea Among Dental Interns in Selected Egyptian Universities: A Cross-Sectional Study","Inclusion Criteria:\n\nDental interns enrolled in selected Egyptian universities. Interns willing to participate voluntarily in the study. Interns able to complete the online questionnaire.\n\nExclusion Criteria:\n\nUndergraduate dental students other than interns. Graduated dentists or postgraduate dentists. Incomplete questionnaire responses. Participants who decline to provide informed consent.",{"count":52,"type":21},350,"Pediatric obstructive sleep apnea (OSA) is a common yet underdiagnosed sleep-related breathing disorder in children that may result in serious health and behavioral complications if left untreated. Dental professionals can play an important role in the early identification and referral of pediatric OSA cases during routine dental examinations. However, limited knowledge and inadequate clinical practices may affect their ability to contribute effectively to patient care. Therefore, this cross-sectional study aims to assess the knowledge, attitude, and practice regarding the management of pediatric obstructive sleep apnea among dental interns in selected Egyptian universities using a validated questionnaire.",[25],[56,57,58,59,60,61,62,63,64],"Pediatric","obstructive","sleep","apnea","Dental interns","knowledge","attitude","practice","egypt","NOT_YET_RECRUITING","2026-05-17",{"date":68,"type":35},"2026-05-22",{"date":70,"type":21},"2026-07-01",{"date":72,"type":21},"2026-09-01",{"name":74,"class":75},"Cairo University","OTHER",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":85,"conditions":86,"keywords":90,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":43},"100581431","observational-study-on-the-impact-of-obstructive-sleep-apnea-on-executive-function-and-empathy-development-in-children-100581431","NCT06850220","Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children","OSA-EFED","Inclusion Criteria:\n\n* Children aged 3-12 years.\n* Diagnosed with OSA due to adenoid and\u002For tonsillar hypertrophy.\n* IQ ≥ 85.\n* Parental consent for participation.\n\nExclusion Criteria:\n\n* Other primary sleep disorders (e.g., narcolepsy, restless leg syndrome).\n* Developmental delay, epilepsy, or other neurological\u002Fmetabolic disorders.\n* Chronic diseases or history of head trauma.",{"count":84,"type":21},150,"This study aims to investigate the effects of obstructive sleep apnea (OSA) on executive function and empathy development in children aged 3-12 years. The study will compare the outcomes of different treatment approaches (surgical vs. pharmacological) in children with mild OSA and track the progression of cognitive and emotional functions over 12 months. The study will also explore potential EEG biomarkers for assessing neurological damage in OSA children.",[25,87,88,89],"Cognition","Empathy","EEG",[91,92,88,93,94,95,96,97],"Obstructive Sleep Apnea","Executive Function","Children","EEG Biomarkers","Cohort Study","Neurodevelopment","Adenotonsillectomy","2026-01-23",{"date":100,"type":35},"2026-01-26",{"date":102,"type":35},"2025-10-13",{"date":104,"type":21},"2027-06-30",{"name":106,"class":75},"Children's Hospital of Soochow University",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":16,"minAge":113,"maxAge":114,"enrollmentInfo":115,"targetDuration":4,"studyType":117,"phases":118,"briefSummary":120,"conditions":121,"keywords":123,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":141},"100581517","pediatric-down-syndrome-post-approval-study-100581517","NCT06851338","Pediatric Down Syndrome Post-Approval Study","Inclusion Criteria:\n\n1. Patient has been diagnosed with Down syndrome;\n2. Patient is 13-18 years of age;\n3. Patient has been diagnosed with severe obstructive sleep apnea, with an AHI of ≥ 10 and ≤ 50 based on a recent (within 6 months of enrollment) qualified in-lab sleep study (PSG);\n4. Patient has documented failure of, or intolerance to, positive airway pressure therapies (such as CPAP or BiPAP) despite attempts to improve compliance;\n5. Patient is contraindicated for, or not effectively treated by, adenotonsillectomy;\n6. Treatment of patient's OSA has followed standard of care in considering all other alternative\u002Fadjunctive therapies;\n7. Patient, and their parents\u002Fguardians, is willing to have stimulation hardware permanently implanted, and be willing to participate in follow-up visits, postoperative in-lab sleep studies (PSGs), and questionnaire completion.\n\nExclusion Criteria:\n\n1. Patient's recent PSG (within 6 months of enrollment) reports central + mixed apneas \\> 25% of the total apnea-hypopnea index (AHI);\n2. Patient has any anatomical finding that would compromise the performance of upper airway stimulation, such as the presence of complete concentric collapse of the soft palate;\n3. Patient has any condition or procedure that has compromised neurological control of the upper airway;\n4. Patient, or their parent\u002Fguardian, is unable or does not have the necessary assistance to operate the patient remote;\n5. Patient is pregnant or plans to become pregnant;\n6. Patient has an implantable device that may be susceptible to unintended interaction with the Inspire system;\n7. Patient will require magnetic resonance imaging (MRI) other than what is specified in the MR conditional labeling;\n8. Patient has a terminal illness with life expectancy of less than 12 months;\n9. Any other reason the investigator deems the patient is unfit for participation in the study.","13 Years","18 Years",{"count":116,"type":21},60,"INTERVENTIONAL",[119],"NA","The purpose of this Post Approval research study is to assess ongoing safety and effectiveness of the Inspire therapy in adolescents and young adults (age 13-18) with Down syndrome and severe sleep apnea. The objective of the study is to provide an ongoing safety and effectiveness assessment of the Inspire UAS System in the Pediatric Down syndrome population.",[25,122],"Down Syndrome (DS)",[124,125,126,127,91,128,129,130],"Pediatrics","OSA","Down Syndrome","Pediatrics OSA","Long-term follow-up","Post Approval Study","PAS","2025-02-24",{"date":133,"type":35},"2025-02-28",{"date":135,"type":21},"2025-02",{"date":137,"type":21},"2030-05",{"name":139,"class":140},"Inspire Medical Systems, Inc.","INDUSTRY",6]