[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pediatric-oncology\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pediatric-oncology":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,41,73,105,129,166,196,228],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100642071","effect-of-the-miroki-companion-robot-on-anxiety-in-pediatric-radiotherapy-100642071",false,"NCT07645950","Effect of the MIROKI Companion Robot on Anxiety in Pediatric Radiotherapy","KOKORO01","Inclusion Criteria:\n\n1. Children aged 4 to 18 years, distributed across the following age groups: 4-7 years, 8-12 years, and 13-18 years.\n2. Child with an indication for radiotherapy treatment at ICM.\n3. Child who speaks French.\n4. Child accompanied by a parent or legal guardian who agrees to participate in the study and provide consent.\n5. Child covered by the French national health insurance system.\n\nExclusion Criteria:\n\n6\\. Child with a diagnosed neurodevelopmental disorder as a comorbidity. 7. Child with postoperative cognitive sequelae that make interaction during care difficult (e.g., language impairment). 8. Total body irradiation. 9. Child under legal protection, unable to express assent, or presenting major difficulties in understanding the study information. Parent Inclusion Criteria\n\n1. Parent of a child enrolled in the study.\n2. Able to speak French.\n3. Willing to participate in the study. Parent Exclusion Criteria\n\n1\\. Parents or legal representatives under legal protection, or presenting an inability to consent or to understand the study information, making it impossible to provide free and informed consent for the minor's participation.",true,"ALL","4 Years",{"count":20,"type":21},6,"ESTIMATED","OBSERVATIONAL","Pediatric radiotherapy is an anxiety-provoking situation that can, on one hand, impair the child's cooperation and require sedation, and on the other hand,burden the care pathway by generating significant anxiety in both the child and their parents. Companion robots represent an innovative avenue for patient support, but they have never been evaluated in the context of radiotherapy. This study examines the effect of MIROKI, the first social robot capable of communication through a Large Multimodal Model (LMM), on children's state anxiety during radiotherapy. An experimental single-case design (SCED) will compare phases with and without the robot (withdrawal\u002Freversal), both in the waiting room and in the irradiation bunker. The primary outcome variable is anxiety, assessed in several ways: through questionnaires at the beginning and end of treatment; through an objective measure of cardiac activity (heart rate in bpm) during the radiotherapy session, with or without the MIROKI robot; and through an observational grid assessing the child's behavior. The intensive repeated measure (bpm) constitutes the preferred variable in this SCED design, while behavioral observation and anxiety questionnaires will support interpretation. The results could pave the way for reducing sedation and improving the overall care pathway in pediatric radiotherapy.",[25,26,27],"Pediatric Oncology","Radiotherapy","Parent","NOT_YET_RECRUITING","2026-06-09",{"date":31,"type":32},"2026-06-12","ACTUAL",{"date":34,"type":21},"2026-07",{"date":36,"type":21},"2027-07",{"name":38,"class":39},"Institut du Cancer de Montpellier - Val d'Aurelle","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":17,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":40},"100643202","canut-junior--assessment-of-sensory-abilities-and-eating-behavior-in-pediatric-oncology-a-feasibility-study-100643202","NCT07632560","CANUT Junior : Assessment of Sensory Abilities and Eating Behavior in Pediatric Oncology: a Feasibility Study","CANUT Junior","Inclusion Criteria:\n\n* Patients treated at a pediatric oncology-hematology center, with an initial diagnosis of a solid or hematological tumor, aged 7 to 17 years inclusive.\n* Patients with functional oral feeding\n* Parent\u002Fguardian who has signed the informed consent form and patient who has not expressed refusal\n* Patients affiliated with the social security system\n* French-speaking patients\n* Validated indication for systematic oncological treatment\n\nExclusion Criteria:\n\n* Individuals with a known food allergy\u002Fintolerance to the prototypes being studied (does not apply to patients on a protected diet)\n* Individuals who have undergone surgery on the tongue\n* Patients for whom other types of cancer treatment are planned during the study period (e.g., radiation therapy)\n* Patients with dental conditions\n* Patients who have relapsed","7 Years","17 Years",{"count":51,"type":21},30,"INTERVENTIONAL",[54],"NA","Cancer treatments in children are very intense and often cause side effects such as nausea, vomiting, loss of appetite, and changes in taste and smell. These sensory alterations can impact eating habits, but they are still poorly understood in children. The study aims to assess whether it is feasible to measure these sensory changes (taste, smell, salivation, and food preferences) in children and adolescents undergoing cancer treatment.\n\nThis study is a feasibility study with 30 patients aged 7 to 17 years, treated at the Pediatric Hematology and Oncology Institute (IHOPE) in Lyon. Sensory tests and questionnaires to evaluate the perceptions, oral health, eating habits, nutritional status, and quality of life are used.\n\nThe inclusion was initially planned at diagnosis, before any administration of chemotherapy. However, the study quickly encountered a recruitment problem due to the emotional impact and medical burden of this initial period of care (study offered to 11 families over a period of 5 months, 3 patients included). An amendment to the protocol was therefore made to be able to modify the inclusion period after the completion of chemotherapy. This modification was implemented on May 15, 2025, and allowed the inclusion of two new patients, making a total of 5 patients. Of these 5 patients, two completed all the tests during V0 and V1, two completed V0 but not V1, one did not complete any of the visits.\n\nThis feasibility phase will help determine whether the tools are suitable and well accepted. The results will be used to design a larger study aimed at better understanding how taste and smell alterations influence the eating behaviors of young patients during cancer treatment. Recruitment will continue for six more months in order to reach the target number of participants.",[57,25],"Pediatric Hematologic Malignancies",[59,60,61,62],"taste alteration","sensory alteration","chemotherapy","pediatrics","RECRUITING","2026-06-02",{"date":66,"type":32},"2026-06-08",{"date":68,"type":32},"2024-12-13",{"date":70,"type":21},"2026-06",{"name":72,"class":39},"Centre Leon Berard",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":52,"phases":85,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":4},"100640136","robotic-dog-intervention-on-emotional-well-being-and-quality-of-life-100640136","NCT07607379","Robotic Dog Intervention on Emotional Well-Being and Quality of Life","Effectiveness and Feasibility of a Robotic Dog Intervention on Emotional Well-Being and Quality of Life in Pediatric Patients With Hematological Malignancies Undergoing HSCT","ROBDOG","Inclusion Criteria:\n\n* Pediatric patients aged 8-15 years\n* Diagnosed with a hematological malignancy and undergoing hematopoietic stem cell transplantation\n* Hospitalized in a protective isolation room during the post-transplant inpatient period\n* Expected to remain hospitalized under isolation for approximately 30 days post-transplant\n* Able to understand and respond to Turkish-language self-report questionnaires\n* Clinically stable and deemed eligible for participation by the treating clinical team\n* Able to interact with the robotic dog at a basic functional level\n\nExclusion Criteria:\n\n* Severe cognitive impairment or neurodevelopmental conditions preventing meaningful interaction or self-report\n* Acute neurological conditions, delirium, or severe psychiatric crisis (e.g., acute agitation, suicidal ideation)\n* Requirement for intensive care, invasive ventilation, or a clinically unstable condition\n* Severe visual, hearing, or motor impairments that prevent interaction with the robotic dog\n* Additional infection control restrictions prevent the placement or use of the robotic dog in the isolation room\n* Anticipated early discharge, transfer, or inability to complete follow-up assessments\n* Severe fear, intolerance, or refusal to interact with robotic or electronic devices","8 Years","15 Years",{"count":84,"type":21},28,[54],"The hematopoietic stem cell transplantation (HSCT) process imposes a substantial psychological burden, leading to impaired emotional well-being due to intensive treatment, isolation, and immunosuppression. Patients often experience social withdrawal, loneliness, and loss of control, which may result in persistent anxiety, depressive symptoms, and reduced quality of life (QoL) if unaddressed. This study aims to evaluate the effectiveness, feasibility, and acceptability of an AI-powered robotic dog in improving emotional well-being and QoL in pediatric patients undergoing HSCT.",[88,89,25],"Emotional Well-being","Quality of Life",[91,92,93,94,95],"technology","pediatric oncohematology","Hematological Malignancy","well-being","nurse","2026-05-19",{"date":98,"type":32},"2026-05-26",{"date":100,"type":21},"2026-07-01",{"date":102,"type":21},"2028-06-30",{"name":104,"class":39},"Koç University",{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":17,"minAge":112,"maxAge":113,"enrollmentInfo":114,"targetDuration":4,"studyType":52,"phases":116,"briefSummary":117,"conditions":118,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":4},"100630849","effect-of-hand-puppet-and-squeeze-toys-on-iv-placement-in-pediatric-oncology-patients-100630849","NCT07493018","Effect of Hand Puppet and Squeeze Toys on IV Placement in Pediatric Oncology Patients","The Effect of Hand Puppet and Squeeze Toy Techniques on Fear, Emotional Expression, and Procedure Success During Peripheral IV Catheter Placement in Pediatric Hematology-Oncology Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\nChildren aged 6-10 years with a pediatric hematology or oncology diagnosis.\n\nCognitively able to understand instructions during the procedure.\n\nRequire peripheral IV catheter placement as determined by the healthcare team.\n\nDifficult Intravenous Access (DIVA) Score ≥4.\n\nChild and parent\u002Fguardian willing to participate.\n\nExclusion Criteria:\n\nPhysical condition preventing use of a squeeze toy.\n\nCognitive or developmental disorders preventing understanding of procedural instructions.\n\n\\-","6 Years","10 Years",{"count":115,"type":21},90,[54],"This randomized controlled trial investigates hand puppet and squeeze toy techniques to reduce fear, emotional distress, and procedure time, and improve IV catheter placement success in 90 pediatric hematology-oncology patients (ages 6-10). Participants will be randomized into three groups: hand puppet, squeeze toy, or control. Outcomes include fear, emotional expression, procedure duration, number of attempts, and first-attempt success.",[119,25],"Pediatric Hematology","2026-03-25",{"date":122,"type":32},"2026-03-30",{"date":124,"type":21},"2026-05",{"date":126,"type":21},"2026-10",{"name":128,"class":39},"Akdeniz University",{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":17,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":141,"conditions":142,"keywords":148,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":165},"100621281","real-world-pediatric-oncology-rehabilitation-in-italy--rewori--100621281","NCT07368582","Real World Pediatric Oncology Rehabilitation in Italy ( ReWori )","Real World Pediatric Oncology Rehabilitation in Italy (ReWori) Study Protocol: Prognostic Factors of Functional Abilities in Children, Adolescents and Young Adults With Cancer Undergoing Rehabilitation","REWORI","Inclusion Criteria:\n\n* Diagnosis of cancer,\n* Children, adolescents and young adults aged between 0 and 24 years old,\n* Children, adolescents and young adults at any stage of treatment and off therapy,\n* Children, adolescents and young adults referred to the Rehabilitation Service of AIEOP centres and Rehabilitation Centres that provide rehabilitation care for paediatric and young adult cancer patients involved in the study.\n\nExclusion Criteria:\n\n* Failure to sign the consent\u002Fassent form for participation in the study by the subject and\u002For by the person exercising parental authority.","0 Months","24 Years",{"count":140,"type":21},249,"This observational study aims to describe changes in the functional abilities of children, adolescents and young adults with cancer who are undergoing physiotherapy or neuropsychomotor rehabilitation. This is real-world study aiming to describe normal rehabilitation pathways in many different hospitals or rehabilitation centres in Italy.\n\nThe primary research question is:\n\n1\\) What are the longitudinal changes in functional abilities among these patients receiving physiotherapy or neuropsychomotor rehabilitation?\n\nThe secondary research questions are:\n\n1. What types of rehabilitation practices are implemented across AIEOP centres?\n2. What are the rehabilitation needs among patients undergoing physiotherapy or neuropsychomotor rehabilitation?\n3. How does health-related quality of life differ across the various stages of the rehabilitation pathway? Participants undergoing usual rehabilitation treatment are evaluated on their functional abilities on a monthly basis. If they agree to participate in this study, the main characteristics of the rehabilitation treatment and the monthly evaluation are collected.",[143,144,25,145,146,147],"Pediatric Cancer","Pediatric Cancer Patients","Rehabilitation","Motor Outcomes","Physical Therapy",[149,150,151,152,153,154,155,156],"pediatric oncology","rehabilitation","motor performance","physical therapy","children","adolescents","young adults","exercise","2026-03-24",{"date":120,"type":32},{"date":160,"type":32},"2024-07-19",{"date":162,"type":21},"2029-09-30",{"name":164,"class":39},"Associazione Italiana Ematologia Oncologia Pediatrica",13,{"id":167,"slug":168,"hasResults":11,"nctId":169,"briefTitle":170,"officialTitle":171,"acronym":4,"eligibilityCriteria":172,"healthyVolunteers":16,"sex":17,"minAge":173,"maxAge":4,"enrollmentInfo":174,"targetDuration":4,"studyType":52,"phases":176,"briefSummary":177,"conditions":178,"keywords":181,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":40},"100625243","easing-scan-anxiety-in-pediatric-oncology-caregivers-through-meditation-based-programs-100625243","NCT07420101","Easing Scan Anxiety in Pediatric Oncology Caregivers Through Meditation-based Programs","A Mindfulness Approach to Scanxiety","Inclusion Criteria:\n\n* Able to understand spoken English and be able to read written English\n* 18 years of age or older\n* Able to understand and willing to sign informed consent document\n* Have access to a smart phone or tablet device that is able to receive texts\n* Is a caregiver of any age oncology patient (including patients above 18 years of age)\n* Caregiver of a patient that is scheduled for a routine scan (CT's, MRI's, PET scans) within the upcoming 3 months\n* If assigned to the Phase 2 intervention group, willing and able to eat a raisin (a box of which will be mailed to home address)\n\nExclusion Criteria:\n\n* Oncology patient is of adult age and caring for self\n* Medically-diagnosed cognitive delay in caregiver (by self-disclosure in eligibility questionnaire)\n* Upcoming scan is due to concern for relapse\u002Fdisease recurrence and is urgent\n* Upcoming scan is part of initial oncology work-up\n* Any non-routine surveillance scan","18 Years",{"count":175,"type":21},160,[54],"\"Scanxiety\" is a term coined to describe anxiety related to imaging during cancer treatment and has not been robustly studied in pediatric oncology caregivers. Mindfulness-based Stress Reduction (MBSR) is a meditation-based program that offers a non-pharmacologic approach to managing stress. The main purposes of this study are two-fold: 1). to determine if scanxiety exists in the caregivers of pediatric oncology patients and 2.) if scanxiety is found, does the implementation of a mindfulness program help to improve caregiver anxiety related to imaging.",[179,180,25],"Caregiver Anxiety","Caregiver Anxiety Related to Cancer Imaging",[182,183,184,185,186],"Scanxiety","caregiver anxiety","caregiver support","meditation","mindfulness","2026-03-17",{"date":189,"type":32},"2026-03-19",{"date":191,"type":32},"2026-02-01",{"date":193,"type":21},"2027-02-01",{"name":195,"class":39},"Kimberley Roche",{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":4,"eligibilityCriteria":202,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":203,"targetDuration":4,"studyType":52,"phases":204,"briefSummary":205,"conditions":206,"keywords":210,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":220,"startDateStruct":222,"completionDateStruct":224,"leadSponsor":226,"locationsCount":40},"100619513","central-venous-catheter-care-training-for-pediatric-oncology-nurses-100619513","NCT07345598","Central Venous Catheter Care Training for Pediatric Oncology Nurses","Training in Central Venous Catheter Care: Effects on Knowledge and Infection Prevention Behaviors of Pediatric Oncology Nurses","Inclusion Criteria:\n\n* Provided care to a pediatric oncology patient at least once\n* Performed a procedure via a central venous catheter on a pediatric oncology patient\n* Voluntarily signed the informed consent form\n\nExclusion Criteria:\n\n* Not having previously performed a procedure via a central venous catheter",{"count":51,"type":21},[54],"The knowledge level of nurses regarding care techniques plays a crucial role in the prevention of central venous catheter-related infections. This study was designed to evaluate the effect of training on central venous catheter care (CVCC), provided to nurses caring for pediatric oncology patients, on their knowledge level and infection prevention behaviors. The study aims to determine the effectiveness of an educational program intended to enhance nurses' knowledge and practical skills in preventing CVC-related infections, thereby contributing to evidence-based practices that improve patient safety.",[143,25,207,208,209],"Central Venous Catheter","Central Venous Catheter Placement","Central Venous Catheter Exit Site Infection",[211,212,209,213,214,215,216,217,218],"Pediatric Nursing","Central venous catheter placement","Nurse training","hand hygiene","knowledge","infection prevention","clinical education","quasi-experimental study","2026-01-07",{"date":221,"type":32},"2026-01-15",{"date":223,"type":21},"2026-01-22",{"date":225,"type":21},"2026-06-22",{"name":227,"class":39},"Fenerbahce University",{"id":229,"slug":230,"hasResults":11,"nctId":231,"briefTitle":232,"officialTitle":233,"acronym":234,"eligibilityCriteria":235,"healthyVolunteers":11,"sex":17,"minAge":236,"maxAge":237,"enrollmentInfo":238,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":240,"conditions":241,"keywords":242,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":250,"lastUpdatePostDateStruct":251,"startDateStruct":253,"completionDateStruct":255,"leadSponsor":257,"locationsCount":40},"100505884","fit-to-fight-childhood-cancer-100505884","NCT05867186","Fit to Fight Childhood Cancer","Fit to Fight Childhood Cancer: an Explorative Long-term Study on Exercise and Its Influence on Physical Performance and Psychosocial Aspects in Childhood Cancer Patients During and After Cancer Treatment.","Kolibri","Inclusion Criteria:\n\n* Oncological disease according to the International Classification of Childhood Cancer.\n* Planned or started anti-cancer treatment (chemo- and\u002For radiotherapy and\u002For surgery) at the Clinic and Polyclinic for Paediatrics and Adolescent Medicine of the University Medical Centre of the Johannes Gutenberg University Mainz or connection to the Paediatric Oncology Centre Mainz within the framework of aftercare.\n* The patient is assessed by the treating team (pediatric oncologist, exercise professional etc.) as suitable to participate in the trial, e.g. due to medical or psychological reasons.\n* Existing informed consent (or assent) to participate in the study.\n* The patient is not in a terminal phase of the disease.\n\nExclusion criteria:\n\n* The patient is assessed by the treating team (pediatric oncologist, exercise professional etc.) as unsuitable to participate in the trial, e.g. due to medical or psychological reasons.\n* After detailed information and, if necessary, having time to consider, the patient (≥ 16 years of age) did not agree to give written informed consent to participate in the trial. In the case of minor patients (\\\u003C16 years of age): The legal guardians do not assume that the child\u002Fadolescent is able to freely decide on participation or to consent to participation on the basis of the information received, and do not consent to this themselves.\n* The patient (and the legal guardians) has\u002Fhave insufficient knowledge of the German or English language, so that it is not possible to carry out both the informed consent and interviews (in age-appropriate language).\n* The patient is in a terminal phase of the disease.","3 Years","21 Years",{"count":239,"type":21},100,"The aim of the study is to investigate the influence of exercise on physical performance and psychosocial aspects in children and adolescents with cancer during and after treatment.",[25],[243,244,245,246,247,248,249],"Paediatric exercise oncology","Precision exercise training","Childhood cancer","Quality of life","Gait","Pain","Cardiorespiratory fitness","2024-12-04",{"date":252,"type":32},"2024-12-09",{"date":254,"type":32},"2023-06-20",{"date":256,"type":21},"2029-07-31",{"name":258,"class":39},"Johannes Gutenberg University Mainz"]