[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pediatric-stroke\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pediatric-stroke":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100598583","bcihome-brain-computer-interface-solutions-to-enable-youth-living-with-severe-disabilities-100598583",false,"NCT07073378","BCI@Home: Brain Computer Interface Solutions to Enable Youth Living With Severe Disabilities","BCI@home","Inclusion Criteria:\n\n* Age 5-18 years\n* Severe motor impairment including inability to walk and minimal functional hand use, and\u002For;\n* Severe communication impairment\n* Ability to follow simple instructions and attend to simple tasks\n* Home environment suitable for the program based on clinician and family discussion;\n* Informed assent\u002Fconsent\n\nExclusion Criteria:\n\n* Epileptic encephalopathy\n* Unstable epilepsy, or\n* Brain imaging incompatible with BCI functionality","ALL","5 Years","18 Years",{"count":20,"type":21},18,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this trial is to evaluate use of brain computer interfaces (BCI) at home for children with severe severe physical disabilities. The main questions it aims to answer are:\n\n1. Can a home BCI program enable children with disabilities to achieve personalized life participation goals?\n2. Can a home BCI program promote implementation reach?",[27,28,29,30],"Cerebral Palsy","Pediatric Stroke","Genetic Condition","Acquired Brain Injury (Including Stroke)",[32],"pediatric brain computer interface","RECRUITING","2026-04-29",{"date":36,"type":37},"2026-05-05","ACTUAL",{"date":39,"type":37},"2025-11-01",{"date":41,"type":21},"2027-08-31",{"name":43,"class":44},"University of Calgary","OTHER",2,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":18,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100310789","the-fbri-vtc-neuromotor-research-clinic-100310789","NCT03325946","The FBRI VTC Neuromotor Research Clinic","Inclusion Criteria:\n\n* Neuromotor Impairment\n\nExclusion Criteria:\n\n* fragile health","3 Months",{"count":54,"type":21},500,"OBSERVATIONAL","The FBRI VTC Neuromotor Research Clinic was established and opened in May of 2013 to provide intensive therapeutic services to individuals with motor impairment secondary to neuromotor disorders. It is direct by Dr. Stephanie DeLuca and based on the principles surrounding ACQUIREc Therapy.\n\nACQUIREc Therapy is an evidenced-based approach to pediatric constraint-induced movement therapy, which refers to a multi-component form of therapy that is focused on helping children who have asymmetric motor abilities between the two sides of the body. Historically, ACQUIREc Therapy has the unimpaired or less impaired upper extremity constrained (by a cast or a splint) while also receiving active therapy from a specially trained therapist who shapes new skills and functional activities with the child's more impaired upper extremity but who is also a licensed Occupational or Physical Therapist (OT\u002FPT). Therapy dosages are high much higher than tradition OT or PT - often lasting many hours per day, up to 6 hours a day, 5 days a week, for 2-4 weeks.\n\nInvestigators have developed further treatments based on the same principles of intensive services combined with behavior shaping for other areas of the body that are also affected by weakness (e.g., the leg and trunk) also, but which usually do not involve constraint. These have been more generally labeled ACQUIRE Therapy.\n\nAll forms involve intensive, play-based therapy for children with asymmetric motor impairments of the arms and hands. The primary focus of treatment is to facilitate the acquisition of new motor skills in the child's weaker body parts through high levels of intensive therapy using scientifically-based behavioral guidelines. Therapy is also delivered in naturalistic environments.\n\nACQUIREc Therapy as a treatment method has been tested in two randomized controlled trials, and a specific manual for its implementation has been developed. Dr. (s) Ramey and DeLuca previously founded a similar clinic, The Pediatric Neuromotor Research Clinic, at the University of Alabama at Birmingham where Dr. DeLuca directed the research clinic for 13 years and oversaw the implementation of the ACQUIREc Therapy treatment protocol in more than 400 cases.\n\nThis research will involve analyzing and interpreting the clinical data of children going through clinical procedures at the FBRI VTC Neuromotor Research Clinic. All participation is voluntary and no children will denied services if families choose not to participate.",[58,27,59,60,61,62,28],"Neuromotor Impairments","Microcephaly","Autism","Trauma, Brain","Acquired Brain Injury","2026-01-16",{"date":65,"type":37},"2026-01-21",{"date":67,"type":37},"2013-01-01",{"date":69,"type":21},"2029-12-31",{"name":71,"class":44},"Virginia Polytechnic Institute and State University",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":84,"conditions":85,"keywords":86,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":72},"100611704","effects-of-modified-cimt-with-and-without-pnf-100611704","NCT07244042","Effects of Modified CIMT With and Without PNF","Effects of Modified Constraint-induced Movement Therapy With and Without Proprioceptive Neuromuscular Facilitation Techniques on Upper Extremity Function in Pediatric Stroke Patients","Inclusion Criteria:\n\n* Paeds Patients with confirmed diagnosis of Stroke\n* Children between age 5 to 13 years\n* Modified Ashworth Scale spasticity level 1 and 2.\n* Patients having Manual Ability Classification System Score between 3 to 6.\n* GMFCS level 1 and 2\n* Patient having in affected upper extremity at least 20◦ of active wrist extension starting from the full flexion, 10◦ of active extension or abduction in the thumb, and 10◦ of active extension in the metacarpophalangeal and interphalangeal joints of the other fingers\n\nExclusion Criteria:\n\n* Patients with epilepsy or seizure disorder\n* Patients with history of botulinum toxin injection, cognitive impairment, fracture and any surgical procedure in upper extremity","13 Years",{"count":82,"type":21},20,[24],"This randomized clinical trial investigates the effects of modified CIMT with and without the addition of PNF techniques on upper extremity function in pediatric stroke patients, aiming to determine whether combining these approaches yields superior motor recovery.This study will be conducted as a randomized clinical trial over an intervention period of six-week. 20 pediatric stroke patients with upper extremity impairments will be randomly assigned to two groups: one receiving modified CIMT alone and the other receiving modified CIMT combined with PNF techniques. Pre- and post-intervention assessments will be conducted using standardized measures, such as Pediatric Motor Activity Log(PMAL) for upper extremity function, Modified Ashworth Scale(MAS) and Manual Ability Classification System(MACS). Muscle tone and physical activity status will also be evaluated. Data will be entered and analyzed in SPSS V-26.0 to compare improvements in motor function between the two groups, with statistical significance assessed to determine the efficacy of each intervention",[28],[87,88,28],"Modified CIMT","Proprioceptive Neuromuscular Facilitation(PNF)","2025-11-17",{"date":91,"type":37},"2025-11-24",{"date":93,"type":37},"2025-10-27",{"date":95,"type":21},"2026-02-10",{"name":97,"class":44},"Riphah International University"]