[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pelvic-floor-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pelvic-floor-disorders":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,19,0,[8,41,73,95,125,150,192,214,245,271,292,311,331,365,388,417,453,479,499],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100577337","phase-1-botox-for-chronic-pelvic-pain-100577337",false,"NCT06796985","Botox for Chronic Pelvic Pain","High-Density Surface Electromyography Guided Precision Botulinum Neurotoxin Injections to Manage Chronic Pelvic Floor Pain","Inclusion Criteria:\n\n1. Females between 18 and 75 years of age\n2. Clinical diagnosis of chronic pelvic pain\n3. Complaints of pain, pressure, or discomfort in the bladder and\u002For pelvic area for the past 6 months or more, associated with lower urinary tract symptoms (such as frequency of urination), in the absence of other explanation of the symptoms (e.g., UTI) \\*\n4. Myofascial pain diagnosed with palpable bands or nodules of contracted muscle fibers\n5. Pelvic muscle tenderness by assessment of pelvic floor muscles on digital pelvic examination\n6. No botulinum neurotoxin pelvic floor muscle injection treatment within 6 months prior to recruitment\n7. Able to provide informed consent\n\nExclusion Criteria:\n\n1. Males\n2. Women \\\u003C 18 and \\> 76 years of age\n3. History of pelvic malignancy and sexual transmitted diseases that is currently not in remission\n4. Bleeding disorder such as coagulopathy\n5. Hypersensitivity to botulinum neurotoxin\n6. Received botulinum neurotoxin pelvic floor muscle injection within 6 months prior to recruitment\n7. History of neurological disorders, such as spinal cord injury, multiple sclerosis, amyotrophic lateral sclerosis or myasthenia gravis\n8. Pregnancy, breast feeding or planning to get pregnant within one year after the last botulinum neurotoxin injection.","FEMALE","18 Years","75 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"PHASE1","The purpose of this research study is to find out if precise, targeted injection of botulinum neurotoxin (commonly known as Botox) provides better relief of pelvic floor hypertonicity and pain than the standard method being used. The researchers want to better understand the effects (good and bad) of targeted botulinum neurotoxin injections in women with pelvic floor disorders.",[27],"Pelvic Floor Disorders","RECRUITING","2026-06-15",{"date":31,"type":32},"2026-06-17","ACTUAL",{"date":34,"type":32},"2025-02-24",{"date":36,"type":21},"2027-03-22",{"name":38,"class":39},"University of Miami","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":40},"100617058","therapeutic-exercise-for-postpartum-recovery-100617058","NCT07313683","Therapeutic Exercise for Postpartum Recovery","Lumbopelvic Stabilization Exercises vs. Hypopressive Exercises for Postpartum Recovery: A Randomized Clinical Trial","PelviRecover","Inclusion Criteria\n\n* Primiparous or multiparous women with an uncomplicated vaginal delivery.\n* Women between 6 and 12 weeks postpartum.\n* Women who have freely read, understood, and signed the informed consent form.\n\nExclusion Criteria\n\n* Cesarean delivery.\n* Pelvic or perineal pain greater than 4\u002F10 during physical examination.\n* Clinical diagnosis of pelvic floor myofascial pain syndrome.\n* Evidence of levator ani muscle avulsion.\n* Third- or fourth-degree perineal tears.\n* History of pelvic surgery.\n* History of pelvic fractures and\u002For pelvic neoplasms.\n* Current pregnancy.\n* Neurological disorders.\n* Active vaginal or urinary tract infections.\n* Cognitive, auditory, or visual impairments that limit comprehension, questionnaire completion, consent, or participation in the study.\n* Individuals under 18 years of age.",{"count":50,"type":21},84,[52],"NA","Pelvic floor dysfunctions (PFDs) are common conditions that affect women, especially after vaginal childbirth. These disorders can cause urinary or fecal incontinence, pain during sexual activity, and prolapse of pelvic organs, leading to a significant decrease in quality of life. Current scientific evidence shows that early and specific physiotherapy-based interventions after childbirth may help reduce the risk of developing long-term PFDs.\n\nPelvic floor muscle training (PFMT) is currently the first-line conservative treatment for women with PFD, but in recent years other exercise methods, such as hypopressive exercises, have become increasingly popular, despite limited supporting evidence. At the same time, some women need to return early to physically demanding jobs or impact sports, but there are no clear guidelines on how to safely prepare the abdominopelvic region for progressive exposure to increased intra-abdominal pressure.\n\nThis study aims to compare two postpartum recovery exercise programs:\n\nA program based on lumbopelvic stabilization exercises that progressively expose women to increases in intra-abdominal pressure and impact activities.\n\nA program based on hypopressive exercises, which focus on avoiding intra-abdominal pressure.\n\nThe goal is to determine which approach is safer and more effective in improving pelvic floor recovery after childbirth and in supporting women in their gradual return to daily, work, and sports activities.",[55,27],"Postpartum Period",[57,58,59,60,61,62],"Therapeutic exercise","Physical therapy","Intra-abdominal pressure","Pelvic floor","Postpartum period","Quality of life","NOT_YET_RECRUITING","2026-04-30",{"date":66,"type":32},"2026-05-04",{"date":68,"type":21},"2026-05-15",{"date":70,"type":21},"2029-02",{"name":72,"class":39},"University of Alcala",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":40},"100627381","early-pelvic-floor-physical-therapy-for-women-undergoing-pelvic-radiation-for-gynecologic-malignancies-100627381","NCT07447895","Early Pelvic Floor Physical Therapy for Women Undergoing Pelvic Radiation for Gynecologic Malignancies","Inclusion Criteria:\n\n1. Participants must be female.\n2. Patients must be 18 years old or older.\n3. Any patient with invasive cervical cancer who is planned for definitive chemoradiation.\n4. Plan to receive a minimum dose of 45Gy to pelvis per investigator.\n5. Willing to undergo pelvic floor physical therapy.\n\nExclusion Criteria:\n\n1. Any previous therapeutic pelvic radiation.\n2. Non-English speaking.",{"count":80,"type":21},28,[52],"This is a single arm phase II study in which 28 patients who will be undergoing definitive pelvic external beam radiation therapy for cervical cancer will receive pelvic floor physical therapy 4 weeks after completing radiation therapy.",[84,85,27],"Cervical Cancer","Radiation Therapy Complication","2026-04-20",{"date":88,"type":32},"2026-04-23",{"date":90,"type":32},"2026-04-16",{"date":92,"type":21},"2030-04-16",{"name":94,"class":39},"University of Cincinnati",{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":101,"sex":16,"minAge":17,"maxAge":102,"enrollmentInfo":103,"targetDuration":4,"studyType":105,"phases":4,"briefSummary":106,"conditions":107,"keywords":113,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":4},"100629706","maternal-musculoskeletal-factors-of-the-hip-lumbopelvic-abdominal-and-pelvic-floor-regions-and-their-association-with-mode-of-delivery-and-postpartum-pelvic-floor-dysfunction-100629706","NCT07478159","Maternal Musculoskeletal Factors of the Hip, Lumbopelvic, Abdominal and Pelvic Floor Regions and Their Association With Mode of Delivery and Postpartum Pelvic Floor Dysfunction","Inclusion Criteria:\n\n* Pregnant women aged 18 years or older\n* Singleton pregnancy\n* Gestational age of 36 weeks at the time of the baseline assessment\n* Receiving prenatal care in primary healthcare centers of Zaragoza (Spain)\n* Ability to understand study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Multiple pregnancy\n* High-risk pregnancy conditions that may affect labor progression or maternal musculoskeletal assessment (e.g., severe obstetric complications requiring planned cesarean section)\n* Previous pelvic floor surgery\n* Neurological or musculoskeletal disorders affecting the lumbopelvic or pelvic floor region\n* Inability to complete the assessment protocol or questionnaires",true,"45 Years",{"count":104,"type":21},376,"OBSERVATIONAL","This prospective observational cohort study aims to investigate the association between maternal musculoskeletal factors of the hip, lumbopelvic, abdominal, and pelvic floor regions and childbirth outcomes, as well as their consequences on pelvic floor function during the postpartum period. A total of 376 pregnant women will be recruited at 36 weeks of gestation and followed until 12 weeks postpartum. Musculoskeletal assessments will include hip range of motion, lumbopelvic mobility, abdominal muscle function, and pelvic floor strength and morphology. Obstetric outcomes such as mode of delivery and perineal trauma will be recorded after childbirth. The study will analyze whether maternal musculoskeletal function during late pregnancy is associated with delivery mode and pelvic floor dysfunction in the postpartum period.",[27,108,109,110,111,112],"Urinary Incontinence","Perineal Trauma","Pelvic Floor Dysfunction","Pregnancy","Puerperium",[27,114,115,108],"Obstetric Labor","Complications Perineal Trauma","2026-03-12",{"date":118,"type":32},"2026-03-17",{"date":120,"type":21},"2026-05-01",{"date":122,"type":21},"2028-01-01",{"name":124,"class":39},"Universitat Internacional de Catalunya",{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":130,"acronym":4,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":136,"conditions":137,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":40},"100591930","phase-4-perineal-massage-using-a-pelvic-wand-during-pregnancy-100591930","NCT06986824","Perineal Massage Using A Pelvic Wand During Pregnancy","A Pilot Study To Assess The Effect Of Antepartum Perineal Massage Using A Pelvic Wand On Labor Agency And Pelvic Health","Inclusion Criteria:\n\n* Pregnant\n* Plan to give birth at BIDMC\n* Age ≥18 years old\n* English language preference\n* 32-36 weeks 'gestation\n\nExclusion Criteria:\n\n* Contraindication to vaginal birth, active genital herpes infection, fetal anomaly requiring cesarean birth).",{"count":133,"type":21},140,[135],"PHASE4","There is limited research on the optimal strategy to reduce obstetric laceration, postpartum urinary retention, and postpartum pelvic pain. In systematic reviews, clinician-directed massage of the perineal muscles at the time of birth and patient directed massage of the perineal muscles in the third trimester to inconsistently reduce the incidence of severe obstetric laceration.1,2 However, there is significant heterogeneity of these studies is due in large part to the lack of a standardized protocols and unpredictability of clinician availability to perform perineal massage around the time of birth.\n\nThe purpose of this study is to understand how perineal massage with a pelvic wand in late pregnancy and during labor influences one's sense of self-control over the labor process and birth experience.",[138,27,139,140],"Pregnancy Related","Obstetric; Injury","Patient Empowerment","2026-03-06",{"date":143,"type":32},"2026-03-09",{"date":145,"type":32},"2025-10-01",{"date":147,"type":21},"2026-09-01",{"name":149,"class":39},"Beth Israel Deaconess Medical Center",{"id":151,"slug":152,"hasResults":11,"nctId":153,"briefTitle":154,"officialTitle":155,"acronym":4,"eligibilityCriteria":156,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":157,"targetDuration":4,"studyType":22,"phases":159,"briefSummary":160,"conditions":161,"keywords":170,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":189,"locationsCount":191},"100622722","phase-4-a-randomized-placebo-controlled-trial-of-nitrous-oxide-during-in-office-bladder-botox-injections-100622722","NCT07387315","A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections","A Randomized, Placebo Controlled Trial of Nitrous Oxide\u002FOxygen Plus Standard Care Versus Standard Care Alone During In-office Intradetrusor onabotulinumtoxinA (Botox) Injections","Inclusion Criteria:\n\n* Adult women ≥18 years old scheduled for in-office intradetrusor botulinum toxin injection and able to consent.\n\nExclusion Criteria:\n\n* Known\u002Fsuspected vitamin B12 or folate deficiency or high-risk state (e.g., pernicious anemia, malabsorption, post-bariatric or strict vegan without supplementation)\n* currently pregnant\n* severe\u002Funstable pulmonary disease or baseline hypoxemia requiring supplemental home oxygen\n* eye or ear surgery in the last six weeks\n* trapped-air conditions (e.g., untreated pneumothorax, bowel obstruction)\n* severe active otitis\u002Fsinus disease\n* inability to follow directions\n* history of adverse reaction to nitrous oxide",{"count":158,"type":21},96,[135],"The goal of this clinical trial is to assess if a mix of nitrous oxide and oxygen can improve pain control during bladder Botox injections. The primary question it aims to answer is: Does using nitrous oxide lower the overall level of pain during the procedure?\n\nResearchers will compare a 50:50 nitrous oxide\u002Foxygen mixture (administered with the Pro-Nox system) plus standard care (with lidocaine in the bladder) to sham mask plus standard care to see if nitrous oxide works better for lowering pain.\n\nParticipants will:\n\n* Receive their bladder Botox injection in the office setting\n* Either use nitrous oxide\u002Foxygen plus standard care during the procedure, or sham mask plus standard care\n* Answer brief questions about pain, anxiety, satisfaction, and willingness to repeat the procedure",[162,163,164,165,108,166,167,168,169,27],"Overactive Bladder","Neurogenic Bladder","Urge Incontinence","Pain","Urinary Bladder, Overactive","Urinary Bladder, Neurogenic","Urinary Bladder Neurogenesis","Urinary Incontinence, Urge",[162,108,164,171,172,173,174,175,176,177,178,179,180,181],"Intradetrusor Injection","OnabotulinumtoxinA","Botox","Bladder Botox","Botulinum Toxins, Type A","Pain Management","Analgesia","Nitrous Oxide","Office-based Procedures","Urogynecology","Pelvic Floor Disorder","2026-01-28",{"date":184,"type":32},"2026-02-04",{"date":186,"type":21},"2026-02",{"date":188,"type":21},"2026-12",{"name":190,"class":39},"TriHealth Inc.",2,{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":197,"acronym":4,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":199,"minAge":17,"maxAge":4,"enrollmentInfo":200,"targetDuration":202,"studyType":105,"phases":4,"briefSummary":203,"conditions":204,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":205,"lastUpdatePostDateStruct":206,"startDateStruct":208,"completionDateStruct":210,"leadSponsor":212,"locationsCount":40},"100412785","evaluation-of-the-subjectively-perceived-pelvic-floor-function-in-patients-with-gynecological-tumors-and-breast-cancer-under-systemic-tumor-therapy-using-a-validated-questionnaire-100412785","NCT04655066","Evaluation of the Subjectively Perceived Pelvic Floor Function in Patients With Gynecological Tumors and Breast Cancer Under Systemic Tumor Therapy Using a Validated Questionnaire","PANTHERA-Studie \"Pelvic Floor Disorders in Patients Under ANtineoplastic THERApy\"","Inclusion Criteria:\n\n* Breastcancer under tumor therapy\n* Gynecological carcinoma under tumor therapy\n\nExclusion Criteria:\n\n* none","ALL",{"count":201,"type":21},200,"3 Years","The multimodal therapy of gynecological malignancies and breast cancer often leads to an impairment of the pelvic floor function. This has a major impact on the quality of life of cancer patients. The aim of the study is to record and analyze the potential subjective impairment of the bladder, bowel and sexual function under systemic tumor therapy as well as possible influencing factors by means of validated disease-specific questionnaires. to find possible starting points for the prevention and treatment of the symptoms.",[27],"2025-09-22",{"date":207,"type":32},"2025-09-23",{"date":209,"type":32},"2018-04-01",{"date":211,"type":21},"2026-12-31",{"name":213,"class":39},"St. Josefs-Hospital Wiesbaden GmbH",{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":4,"eligibilityCriteria":220,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":221,"enrollmentInfo":222,"targetDuration":4,"studyType":22,"phases":224,"briefSummary":226,"conditions":227,"keywords":231,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":235,"lastUpdatePostDateStruct":236,"startDateStruct":238,"completionDateStruct":240,"leadSponsor":242,"locationsCount":40},"100444090","early-phase-1-a-novel-medical-system-for-quantitative-diagnosis-and-personalized-precision-botulinum-neurotoxin-injection-in-chronic-pelvic-pain-management-100444090","NCT05062902","A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management","An Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management","Inclusion Criteria:\n\n* Inclusion criteria for interstitial cystitis\u002Fbladder pain syndrome (IC\u002FBPS) patients will be:\n\n  1. Woman aged 18 to 60.\n  2. Have a clinical diagnosis of IC\u002FBPS.\n  3. Pain, pressure, or discomfort in the bladder and\u002For pelvic area for the past 6 months or more, associated with lower urinary tract symptoms (such as frequency of urination), in the absence of other explanation of the symptoms (e.g., urinary tract infection).\n  4. Myofascial pain diagnosed with palpable contracted muscle fibers.\n  5. Pelvic muscle tenderness by assessment of pelvic floor muscles on digital pelvic examination.\n  6. Pelvic floor hypertonicity (PFH), measured using vaginal manometry (pressure \\> 35 cm∙H2O).\n  7. Ability to provide informed consent.\n\nExclusion Criteria:\n\n* Exclusion criteria consist of the following:\n\n  1. History of pelvic malignancy and sexually transmitted diseases.\n  2. Bleeding disorder such as coagulopathy\n  3. History of neurological disorders, such as spinal cord injury, multiple sclerosis, amyotrophic lateral sclerosis or myasthenia gravis.\n  4. Pregnancy, breast feeding or desiring for pregnancy in the coming year.\n  5. Subjects with history of pelvic surgery (e.g., pain from mid-urethral sling or pelvic mesh),\n  6. Pelvic malignancy (urinary tract, gynecologic, gastrointestinal)\n  7. Active fistula\n  8. Radiation cystitis\n  9. Cyclophosphamide cystitis\n  10. Pre-existing anorectal disorders\n  11. Infections near the injection sites\n  12. History of drug or alcohol abuse\n  13. Hypersensitivity to BoNT\n  14. Steroids or hormone usage will be carefully considered by the research team for inclusion.\n\nParticipants with on-going BoNT therapies will not be screened until the complete drug washout is confirmed.","60 Years",{"count":223,"type":21},46,[225],"EARLY_PHASE1","The purpose of this study is to evaluate if it is possible to use intravaginal high-density surface electromyography to guide Botulinum neurotoxin (BoNT) injection to treat pelvic floor muscle overactivity that complicates Chronic Pelvic Pain (CPP).",[228,229,230,27],"Interstitial Cystitis","Chronic Pain","Pelvic Floor; Relaxation",[232,233,234],"hypertonicity","chronic pelvic pain","electromyography","2025-08-14",{"date":237,"type":32},"2025-08-19",{"date":239,"type":21},"2025-09-15",{"date":241,"type":21},"2027-12-01",{"name":243,"class":244},"HillMed Inc.","INDUSTRY",{"id":246,"slug":247,"hasResults":11,"nctId":248,"briefTitle":249,"officialTitle":250,"acronym":4,"eligibilityCriteria":251,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":252,"targetDuration":4,"studyType":105,"phases":4,"briefSummary":254,"conditions":255,"keywords":257,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":262,"lastUpdatePostDateStruct":263,"startDateStruct":265,"completionDateStruct":267,"leadSponsor":269,"locationsCount":40},"100551526","pelvic-floor-rehabilitation-of-female-pelvic-floor-dysfunction-100551526","NCT06461234","Pelvic Floor Rehabilitation of Female Pelvic Floor Dysfunction","Establishment of an Artificial Intelligence Multidimensional Early Warning Diagnostic and Prognostic Model of Pelvic Floor Rehabilitation Therapy in the Chinese Population: a Prospective Cohort Study.","Inclusion Criteria:\n\n1. knowledge of the study, voluntary enrolment in the study, and signing of informed consent;\n2. postpartum pelvic floor weakness (pelvic floor muscle strength less than grade 3), or mild to moderate pelvic organ prolapse (POP-Q staging less than stage III), or pelvic organ prolapse combined with dysfunction (bowel or bladder dysfunction).\n\nExclusion Criteria:\n\n1. history of comorbid serious medical or surgical illness;\n2. comorbid psychiatric disorders;\n3. contraindications to electrical and magnetic stimulation such as implanted pacemakers;\n4. pelvic malignancy, acute genitourinary infection or vaginal bleeding, and genital tract malformation.",{"count":253,"type":21},1360,"The goal of this observational study is to learn about the therapeutic effects of different pelvic floor rehabilitation treatments, including pelvic floor muscle training , pelvic floor biofeedback electrical stimulation, and magnetic stimulation, in a population of Chinese patients with female pelvic floor dysfunction disorders. The study aims to find out the individualised pelvic floor rehabilitation treatment plan suitable for the Chinese population. The main question it aims to answer is:\n\n1. Do patients with reduced pelvic floor muscle strength after childbirth, or patients with mild to moderate pelvic organ prolapse and symptomatic pelvic organ prolapse benefit from pelvic floor rehabilitation?\n2. Is the combination of biofeedback electrical stimulation plus pelvic floor magnetic stimulation superior to single electrical stimulation, magnetic stimulation or pelvic floor muscle training?\n3. Which pelvic floor rehabilitation therapy is most suitable for Chinese patients with female pelvic floor dysfunction?\n4. What factors are early predictors of developing female pelvic floor dysfunction? And what factors can predict the prognostic status of patients treated with pelvic floor rehabilitation? Participants in the multicenter will be treated with different rehabilitation therapies, during which the researchers will collect clinical symptoms using the PFDI20 questionnaire, and POP-Q scores, pelvic floor muscle strength, and electromyography results from participants before, at the end of, and 3 months and 1 year after the end of treatment.",[27,256],"Pelvic Organ Prolapse",[256,258,259,260,261],"pelvic floor rehabilitation","pelvic floor muscle training","biofeedback electrical stimulation","magnetic stimulation","2025-07-29",{"date":264,"type":32},"2025-08-01",{"date":266,"type":32},"2024-05-20",{"date":268,"type":21},"2026-11-30",{"name":270,"class":39},"Mingfu Wu",{"id":272,"slug":273,"hasResults":11,"nctId":274,"briefTitle":275,"officialTitle":276,"acronym":4,"eligibilityCriteria":277,"healthyVolunteers":101,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":278,"targetDuration":4,"studyType":105,"phases":4,"briefSummary":280,"conditions":281,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":283,"lastUpdatePostDateStruct":284,"startDateStruct":286,"completionDateStruct":288,"leadSponsor":290,"locationsCount":40},"100582748","monocentric-prospectiv-observational-clinical-trial-of-pelvic-floor-biometry-during-pregnancy-and-puerperium-100582748","NCT06867341","Monocentric Prospectiv Observational Clinical Trial of Pelvic Floor Biometry During Pregnancy and Puerperium","Monocentric Prospectiv Observational Clinical Trial of Pelvic Floor Biometry During Pregnancy and Puerperium : Relationship with Symptoms Related to Post-partum Pelvic Floor Dysfunction","Inclusion Criteria:\n\n* single pregnancy confirmed by ultrasound in the first trimester (within 10 weeks of gestational age),\n* maternal age between 18 and 40 years,\n* patients who speak Italian correctly and\u002For who can perfectly understand what was expressed at the time of enrollment.\n* spontaneous vaginal births, operative and current cesarean section\n* patients who do not report urinary and fecal incontinence or pelvic organ prolapse at enrollment.\n\nExclusion Criteria:\n\n* previous pregnancy ended with spontaneous vaginal delivery or cesarean section\n* pelvic floor reconstructive surgery\n* gynecological cancer\n* pelvic radiation therapy for previous oncological disease\n* previous pelvic trauma\n* known connective tissue disease\n* body mass index \\>40 kg \u002F m2.",{"count":279,"type":21},350,"Pregnancy, childbirth and the puerperium determine significant changes in the muscular, fascial and support structures of the pelvic floor. These changes, both physiological (i.e. dictated by the adaptations that pregnancy determines at the level of the connective tissue, collagen and pelvic-perineal muscular structures) and the changes induced by the passage of the fetus through the birth canal (obstetric lacerations, episiotomy and muscle avulsions) cause a weakening of the pelvic support structures with the possible onset of dysfunctional symptoms, which are not only common in old age, but become evident already in childbearing age. Previous studies on the composition of connective tissue show significant changes in the collagen component both in continent women and in those who experience stress urinary incontinence. These changes are revealed in approximately 24% of the population that suffers from urinary incontinence. Collagen is the main component of the endopelvic fascia. During pregnancy, the hormonal influence typical of this phase determines significant changes in the mechanical properties of the connective tissue and muscle fibers of the levator ani, which tend to hypertrophy and lengthen. This may also explain why cesarean delivery, elective or after the onset of labor, is not fully protective against the development of pelvic floor dysfunction. However, pelvic floor changes may have occurred before delivery and may not necessarily be related to labor and delivery itself. Incontinence, mostly temporary in pregnancy, must be interpreted as the result of these factors in addition to the increased pressure on the urethrovesical junction caused by the gravid uterus. Stretching of connective tissues beyond their physiological limits during labor, resulting in levator ani injury and\u002For possible neurogenic stretch damage, occurs in the majority of women who give birth vaginally, but in most women, muscle hypertrophy and nerve fiber adaptation compensate for this pathological pattern. In a minority (5-20%) of women, major levator ani defects and neurogenic lesion may lead to irreversible changes in pelvic floor function. Pelvic floor imaging after pregnancy has improved the understanding of the etiology of pelvic floor disorders in animal models. Patients who already present with pelvic static dysfunction and urinary incontinence during pregnancy tend to develop the same problems in the puerperium. However, to date it is not known what moment in pregnancy these changes in the pelvic tissue begin and that cause the progressive change in the myo-connective components of pregnancy. The lack of prospective cohort studies of pregnant and postpartum subjects does not allow a conclusive opinion on this topic. Pelvic floor ultrasound performed transpeineally, useful for evaluating pelvic biometry, is a non-invasive method and well tolerated by the patient, not only in postpartum but also during pregnancy. A previous study examined pelvic floor changes during pregnancy, reporting how the progression of pregnancy determines changes in the anatomical components of the pelvic floor, without however correlating the data with the puerperium and the longer-term outcomes of these changes. We did not identify any previously published studies that attempted to comprehensively assess biometric changes of the pelvic floor during pregnancy and postpartum using not only ultrasound imaging, but also clinical assessment and validated urinary symptom questionnaires.",[27,282],"Pelvic Floor Distress and Impact Scores","2025-03-07",{"date":285,"type":32},"2025-03-10",{"date":287,"type":32},"2023-01-17",{"date":289,"type":21},"2029-12-31",{"name":291,"class":39},"Fondazione IRCCS Policlinico San Matteo di Pavia",{"id":293,"slug":294,"hasResults":11,"nctId":295,"briefTitle":296,"officialTitle":296,"acronym":4,"eligibilityCriteria":297,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":298,"enrollmentInfo":299,"targetDuration":4,"studyType":105,"phases":4,"briefSummary":301,"conditions":302,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":303,"startDateStruct":305,"completionDateStruct":307,"leadSponsor":309,"locationsCount":40},"100578226","pelvic-floor-dysfunction-among-female-physiotherapy-students-a-cross-sectional-study-100578226","NCT06808542","Pelvic Floor Dysfunction Among Female Physiotherapy Students: A Cross-Sectional Study","Inclusion Criteria:\n\n* Virgin undergraduate physiotherapy students.\n* Their age will range from 18-25 years.\n\nExclusion Criteria:\n\n* Neurological disorders or injuries that may affect pelvic floor function (e.g., fibromyalgia and multiple sclerosis).\n* Mental health or cognitive disorders that could affect data collection.\n* Females who have undergone any form of abdominal surgery prior to the time of the study.\n* Females with current use of medications that may affect pelvic floor function (e.g., anticholinergics, opioids, antidepressants).","25 Years",{"count":300,"type":21},180,"This study aims to:\n\n1. estimate the prevalence of pelvic floor dysfunction among female physiotherapy students at Cairo University.\n2. identify potential risk factors that may be associated with pelvic floor dysfunction in this student population.\n3. assess the level of awareness regarding pelvic floor health among female physiotherapy students at Cairo University.\n4. explore how female physiotherapy students at Cairo University utilize available healthcare resources for managing pelvic floor-related concerns.",[27],{"date":304,"type":32},"2025-02-25",{"date":306,"type":32},"2025-02-04",{"date":308,"type":21},"2025-04-25",{"name":310,"class":39},"Cairo University",{"id":312,"slug":313,"hasResults":11,"nctId":314,"briefTitle":315,"officialTitle":315,"acronym":4,"eligibilityCriteria":316,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":317,"targetDuration":4,"studyType":22,"phases":319,"briefSummary":320,"conditions":321,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":322,"lastUpdatePostDateStruct":323,"startDateStruct":325,"completionDateStruct":327,"leadSponsor":329,"locationsCount":40},"100578779","multicenter-study-on-the-correction-of-prolapse-via-laparoscopy-100578779","NCT06815731","Multicenter Study on the Correction of Prolapse Via Laparoscopy","Inclusion Criteria:\n\n* Patients with Stage II- IV primary or recurrent prolapse affecting the anterior or middle vaginal compartment with or without minimal posterior defect (Stage I) according to the POP-Q.\n\nExclusion Criteria:\n\n* History of abdominal prolapse reconstructive surgery.\n* History of prolapse reconstructive surgery with vaginal meshes.\n* Stage I according to the POP-Q classification or asymptomatic prolapse.\n* Medical contraindication for general anaesthesia.\n* Patient preference for vaginal surgical treatment.\n* Patient does not wish to participate in the study.",{"count":318,"type":21},181,[52],"In the laparoscopic lateral suspension (LLS) technique, the fixation of the mesh as a prosthetic element for correcting anterior apical vaginal prolapse at the level of the dome or uterus can offer anatomical and functional results that are not inferior to those of the conventional surgical technique, minimize possible intraoperative complications and facilitate the specific learning curve of sacropexy.",[27],"2025-02-06",{"date":324,"type":32},"2025-02-07",{"date":326,"type":32},"2023-10-01",{"date":328,"type":21},"2026-05-30",{"name":330,"class":39},"Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia",{"id":332,"slug":333,"hasResults":11,"nctId":334,"briefTitle":335,"officialTitle":336,"acronym":4,"eligibilityCriteria":337,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":338,"enrollmentInfo":339,"targetDuration":4,"studyType":22,"phases":340,"briefSummary":341,"conditions":342,"keywords":346,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":356,"lastUpdatePostDateStruct":357,"startDateStruct":359,"completionDateStruct":361,"leadSponsor":363,"locationsCount":40},"100575860","effects-of-reformer-pilates-in-pregnant-women-100575860","NCT06777771","Effects of Reformer Pilates in Pregnant Women","The Effects of Reformer Pilates on Pain, Functional Capacity, Lumbopelvic Stabilization, Abdominal Muscles, Respiratory Functions, Pelvic Floor Function, and Venous Insufficiency in Pregnant Women","Inclusion Criteria:\n\n* Single pregnancy\n* Primiparous pregnancy\n* Adult pregnant women (between 18-35 years old)\n* Pregnant women whose gestational week is 11-22 weeks\n* Pregnant women with a body mass index \\\u003C30\n* Ability to read and write\n\nExclusion Criteria:\n\n* Multiple pregnancies\n* Having a history of abdominal surgery\n* Having one of the conditions in which exercise is contraindicated, such as heart disease, severe lung disease, continuous bleeding in the second and third trimesters, placenta previa, risk of premature birth, rupture of membranes, preeclampsia, severe anemia\n* Not volunteering to participate in the study\n* Not participating in more than 90% of the training sessions","35 Years",{"count":20,"type":21},[52],"Pregnancy is known as a period associated with important physiological and psychological changes in women's lives. There is moderately sufficient evidence in the literature to recommend supplementing prenatal physical activity for maternal health benefits. It has been reported that physical exercise by pregnant women in the absence of obstetric contraindications will not pose a risk to the health of the mother and fetus. In the literature, there are no studies examining the effects of reformer pilates on pain, functional capacity, lumbopelvic stabilization, diastasis recti abdominis, abdominal muscle thickness, respiratory functions, pelvic floor dysfunction, urinary incontinence, sexual function, and venous insufficiency in pregnant women. Therefore, this study aimed to investigate the effects of reformer pilates on pain, functional capacity, lumbopelvic stabilization, diastasis recti abdominis, abdominal muscle thickness, respiratory functions, pelvic floor dysfunction, urinary incontinence, sexual function, and venous insufficiency in pregnant women.",[138,27,343,344,345],"Pain, Back","Pain, Neck","Pregnancy, Abdominal",[111,347,348,349,110,350,351,352,353,354,108,355,165],"Exercise","Reformer Pilates","Pilates","Lumbopelvic Stabilization","Functional Capacity","Respiratory Function","Abdominal Muscle Thickness","Venous Insufficiency","Sexual Function","2025-01-15",{"date":358,"type":32},"2025-01-16",{"date":360,"type":32},"2024-02-06",{"date":362,"type":21},"2025-09",{"name":364,"class":39},"Izmir Democracy University",{"id":366,"slug":367,"hasResults":11,"nctId":368,"briefTitle":369,"officialTitle":370,"acronym":371,"eligibilityCriteria":372,"healthyVolunteers":101,"sex":16,"minAge":17,"maxAge":373,"enrollmentInfo":374,"targetDuration":4,"studyType":22,"phases":376,"briefSummary":377,"conditions":378,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":380,"lastUpdatePostDateStruct":381,"startDateStruct":383,"completionDateStruct":384,"leadSponsor":386,"locationsCount":40},"100538845","perineal-massage-in-pregnancy-to-reduce-the-levator-ani-coactivation-100538845","NCT06296134","Perineal Massage in Pregnancy to Reduce the Levator Ani Coactivation","Does Perineal Massage in Pregnancy Reduce the Levator Ani Muscle Co-activation?","CO-LAM23","Inclusion Criteria: pregnant women with the following characteristics:\n\n* nulliparous\n* single pregnancy\n* cephalic presentation of the fetus\n* Italian language fluency\n\nExclusion Criteria:\n\n* multiparous\n* age \\\u003C 18 y, age \\> 40 y\n* previous urinary or fecal incontinence\n* contraindications to vaginal delivery (such as placenta previa, vasa previa, etc)\n* twin pregnancy\n* language barrier\n* BMI at or \\> 30","40 Years",{"count":375,"type":21},58,[52],"The goal of this clinical trial is to test the efficacy of the perineal massage in reducing the levator ani muscle (LAM) co-activation. This phenomenon is characterized by the LAM contraction rather than its relaxation during the Valsalva maneuver and it is associated with adverse obstetric outcome. Participants who co-activate will be enrolled and randomized in 2 groups: group A, where women themselves perform the perineal massage during the third trimester of pregnancy and group B, where women undergo the standard care. Researchers will compare these groups to see if the perineal massage is able to reduce LAM co-activation.",[27,379],"Levator Ani Syndrome","2024-08-01",{"date":382,"type":32},"2024-08-02",{"date":380,"type":32},{"date":385,"type":21},"2025-12-31",{"name":387,"class":39},"Azienda Sanitaria Universitaria Friuli Centrale",{"id":389,"slug":390,"hasResults":11,"nctId":391,"briefTitle":392,"officialTitle":393,"acronym":394,"eligibilityCriteria":395,"healthyVolunteers":101,"sex":199,"minAge":396,"maxAge":4,"enrollmentInfo":397,"targetDuration":4,"studyType":22,"phases":399,"briefSummary":400,"conditions":401,"keywords":406,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":408,"lastUpdatePostDateStruct":409,"startDateStruct":411,"completionDateStruct":413,"leadSponsor":415,"locationsCount":40},"100555970","effectiveness-of-pelvic-floor-exercise-to-prevent-lars-low-anterior-resection-syndrome-100555970","NCT06519006","Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome)","Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome) After Mini-invasive Low Anterior Resection in Patients With Rectal Cancer","CH1","Inclusion Criteria:\n\n* Cognitive functions make it possible to understand and sign the patient\\'s informed consent and consent to participate in the study\n* Surgical procedure - mini-invasive low anterior rectal resection\n\nExclusion Criteria:\n\n* not agreeing to participate in the study\n* request to practice pelvic floor exercises despite being in the control group\n* non-compliance\n* serious psychiatric diagnoses","19 Years",{"count":398,"type":21},50,[52],"The main aim of this randomized study will be to determine the effectiveness of pelvic floor exercises on the incidence or severity of LAR syndrome in patients after mini-invasive rectal resection.\n\nThe main questions it aims to answer are:\n\n* Does pelvic floor exercise after low anterior resection prevent LARS (low anterior resection syndrome)?\n* What is the adherence of patients to prescribed home exercise after surgery?\n* Quality of life after LAR\n\nResearchers will compare the group of patients with pelvic floor exercises to those without and determine the occurrence and severity of LARS.\n\nParticipants will:\n\n* under the professional guidance of a physiotherapist, the day before surgery and in the first 4 postoperative days be educated to exercise the pelvic floor\n* continue exercise at home for a month (according to the instructions together with the infographic)",[402,403,27,404,405],"Prevention","LARS - Low Anterior Resection Syndrome","Rectal Cancer","Low Anterior Resection",[407],"prevention, LARS, pelvic floor exercise, LAR","2024-07-19",{"date":410,"type":32},"2024-07-25",{"date":412,"type":32},"2024-04-01",{"date":414,"type":21},"2026-05",{"name":416,"class":39},"F. D. Roosevelt University Hospital",{"id":418,"slug":419,"hasResults":11,"nctId":420,"briefTitle":421,"officialTitle":421,"acronym":422,"eligibilityCriteria":423,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":102,"enrollmentInfo":424,"targetDuration":4,"studyType":22,"phases":426,"briefSummary":427,"conditions":428,"keywords":435,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":444,"lastUpdatePostDateStruct":445,"startDateStruct":447,"completionDateStruct":449,"leadSponsor":451,"locationsCount":40},"100480030","correlation-pelvic-floor-function-and-ultrasound-findings-one-year-after-childbirth-100480030","NCT05530681","Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth","DeliverUU","Inclusion Criteria:\n\n* age = or \\> 18 years\n* Dutch\u002FEnglish-speaking\n* \\> 33 weeks gestation\n* delivering in UZ Leuven\n* vaginal delivery\n\nExclusion Criteria:\n\n* age \\\u003C 18 years\n* not Dutch\u002FEnglish-speaking\n* \\\u003C 33 weeks gestation\n* not delivering in UZ Leuven\n* non-vaginal delivery\n* Any disorder, that independently from delivery, affects pelvic floor function or structure, such as, but not limited to musculoskeletal or neurologic diseases.\n* any women with drug addiction, cognitive deficit, language-barrier and illiteracy\n* any disorder or timing or circumstances, which in the Investigator's opinion represents an obstacle to proper informed consent, or safe and\u002For compliant participation.\n* any prior or simultaneous treatment(s) potentially jeopardising safety or compromising trial integrity.",{"count":425,"type":21},320,[52],"This is a single-center prospective cohort study sponsored by the University Hospitals Leuven (UZ). Women will undergo a pelvic floor ultrasound and will be asked to fill out a questionnaire at the time of their admission into the labour suite, at the postpartum check-up and 12 months postpartum.\n\nThe primary objective is to correlate self-reported symptoms of Pelvic Floor Dysfunction (PFD) (binary outcome) at one year after delivery with structural changes to the Pelvic Floor Muscles (PFM) and postpartum evidence of levator avulsion (binary indicator) as measured by TransPerineal UltraSound (TPUS).\n\nSecondary objectives are to compare demographical and obstetrical variables between patients suffering from PFD symptoms or pelvic floor injury (documented one year after delivery) and those who do not; to record how patients manage and cope with PFD including recovery and compliance with Pelvic Floor Muscle Training (PFMT) as prescribed in the standard pathway of peripartum care; and to use of TPUS images for the development of artificial intelligence tools for automated image analysis.\n\nPrimary outcomes are PFD symptoms one year after delivery and injury to the PFM evidenced by POP-Q and TPUS. The demographic variables and information about the pregnancy and the delivery will be obtained from the medical records.\n\nThe presence and severity of PFD will be measured using standardized self-reporting tools: Pelvic Organ Prolapse Distress Index (POP-DI), Patient Assessment Constipation-SYMptoms (PAC-SYM), International Consultation on Incontinence Questionnaire - Urinary Incontinence - Short Form (ICIQ-SF), St. Mark's Incontinence Score (SMIS), Female Sexual Function Index (FSFI), Female Sexual Distress Scale - Revised (FSDS-R). FSFI is a widely used generic tool with sufficient granularity and validated in a large number of languages. FSDS-R assesses the construct \"personal distress\", which has been considered as an additional important aspect contributing to sexual dysfunction of women.\n\nPFD, as a clustered outcome, being the presence of any kind of pelvic floor dysfunction symptoms, will be defined as POP-DI score of ≥11 OR ICIQ-SF score of ≥1 OR SMIS score of ≥1 OR FSFI score ≤ 26.55 OR FSDS-R score ≥11.",[27,429,108,430,256,431,432,433,434],"Obstetric Trauma","Anal Incontinence","Pelvic Pain","Sexual Dysfunction","Constipation","Anal Sphincter Injury",[436,437,438,439,440,441,442,443],"urinary incontinence","anal incontinence","pelvic organ prolapse","sexual dysfunction","constipation","postpartum","levator avulsion","anal sphincter injury","2024-06-28",{"date":446,"type":32},"2024-07-01",{"date":448,"type":32},"2022-08-17",{"date":450,"type":21},"2025-09-01",{"name":452,"class":39},"Universitaire Ziekenhuizen KU Leuven",{"id":454,"slug":455,"hasResults":11,"nctId":456,"briefTitle":457,"officialTitle":458,"acronym":4,"eligibilityCriteria":459,"healthyVolunteers":101,"sex":16,"minAge":460,"maxAge":4,"enrollmentInfo":461,"targetDuration":4,"studyType":105,"phases":4,"briefSummary":463,"conditions":464,"keywords":465,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":471,"lastUpdatePostDateStruct":472,"startDateStruct":474,"completionDateStruct":476,"leadSponsor":478,"locationsCount":40},"100551058","prevalence-of-pelvic-floor-dysfunctions-in-female-badminton-athletes-and-sedentary-100551058","NCT06455150","Prevalence of Pelvic Floor Dysfunctions in Female Badminton Athletes and Sedentary","Prevalence of Pelvic Floor Dysfunctions in Female Badminton Athletes and Sedentary: Protocol of an Observational Case-Control Study","Inclusion Criteria:\n\n* Cases: women who practice recreational badminton and\u002For are federated and compete.\n* Controls: sedentary women and\u002For do not meet the recommendations of the World Health Organization (150-300 minutes of moderate-intensity aerobic physical activity or 75-150 minutes of vigorous-intensity aerobic physical activity).\n\nExclusion Criteria:\n\n* Connective tissue diseases (Ehlers-Danlos syndrome, Marfan syndrome or hypermobility syndrome).\n* Pregnant at the time of the study.\n* Give birth in the last 12 months.\n* Not understanding Spanish language.","20 Years",{"count":462,"type":21},100,"The objective of the study is to know the prevalence of pelvic floor dysfunctions in female badminton athletes compared to sedentary women, and the hypothesis is that the prevalence of pelvic floor dysfunctions is going to be higher in female badminton athletes.",[27],[466,467,468,469,470],"prevalence","pelvic floor disorders","racquet sports","sedentary behavior","women","2024-06-11",{"date":473,"type":32},"2024-06-12",{"date":475,"type":21},"2024-09",{"date":477,"type":21},"2025-02",{"name":72,"class":39},{"id":480,"slug":481,"hasResults":11,"nctId":482,"briefTitle":483,"officialTitle":484,"acronym":4,"eligibilityCriteria":485,"healthyVolunteers":101,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":486,"targetDuration":4,"studyType":105,"phases":4,"briefSummary":487,"conditions":488,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":490,"lastUpdatePostDateStruct":491,"startDateStruct":493,"completionDateStruct":495,"leadSponsor":496,"locationsCount":40},"100499076","the-intermediate-and-long-term-follow-up-of-home-based-pelvic-muscle-training-100499076","NCT05778552","The Intermediate and Long-term Follow up of Home Based Pelvic Muscle Training","The Intermediate and Long-term Follow up of Home Based Pelvic Muscle Training : Prospective Study","Inclusion Criteria:\n\n* Age \\> 18-year-old, non-pregnancy, SUI, bladder capacity \\> 300ml, RU\\\u003C150ml, pelvic organ prolapse\n\nExclusion Criteria:\n\n* recurrent UTI, cancer patients, chronic pelvic pain, psychologic problems",{"count":201,"type":21},"When participants present with symptoms of pelvic organ prolapse (POP) and stress urinary incontinence (SUI), the investigators will perform a comprehensive evaluation and initially provide conservative treatment. If conservative treatment fails, invasive treatment will be considered. The investigators will arrange a pelvic muscle training course two to three times a week for a duration of 1.5 months per course. However, participants may complain about the inconvenience of traffic, which may lead to discontinuation of the pelvic training course. Therefore, the investigators propose the development of a home-based pelvic muscle training device and will collaborate with information engineering specialists at Tamkang University to invent the device for home-based pelvic muscle training.",[27,256,489],"Stress Urinary Incontinence","2023-03-09",{"date":492,"type":32},"2023-03-21",{"date":494,"type":21},"2023-04-01",{"date":211,"type":21},{"name":497,"class":498},"Taipei Veterans General Hospital, Taiwan","OTHER_GOV",{"id":500,"slug":501,"hasResults":11,"nctId":502,"briefTitle":503,"officialTitle":504,"acronym":505,"eligibilityCriteria":506,"healthyVolunteers":101,"sex":16,"minAge":17,"maxAge":102,"enrollmentInfo":507,"targetDuration":4,"studyType":22,"phases":509,"briefSummary":510,"conditions":511,"keywords":527,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":542,"lastUpdatePostDateStruct":543,"startDateStruct":545,"completionDateStruct":547,"leadSponsor":549,"locationsCount":40},"100439987","hiit-vs-mict-during-pregnancy-and-health-and-birth-outcomes-in-mothers-and-children-100439987","NCT05009433","HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children","The Effect of Pre- and Postnatal High Intensity Interval Training and Moderate Intensity Continuous Training on Biological, Functional and Psychological Markers of Pregnancy Disorders and Non-communicable Diseases in Mothers and Offsprings","HIIT MAMA","Inclusion Criteria:\n\nCriteria: Inclusion Criteria:\n\nFor pregnant women:\n\n1. course of pregnancy allowing participation in physical activities adapted to pregnant women\n2. consent of the obstetric care provider to participate in the study tests and exercise classes;\n3. taking part in all diagnostic and control tests to assess selected biological, functional and psychological parameters at each trimester of pregnancy, during the puerperium and one year after childbirth;\n4. participant's consent to use data from the medical documentation on the course of childbirth and the assessment of the new-born, as well as the results of preventive examinations in children aged one, two, four and six, routinely performed according to the Polish pediatric care system;\n5. availability to participate in classes three times a week until the day of delivery;\n6. declaration of participation in postpartum classes at least once a week and self-completion of the exercise program according to written instructions prepared by the exercise specialist;\n7. women can participate in the exercise programs regardless of their level of fitness or exercise capacity, as well as the level of motor skills (based on the diagnostic exercise tests, the exercise program will be tailored to the individual needs and capabilities of a woman).\n\nFor nonpregnant women:\n\n1. nulliparous;\n2. lack of diagnosed infertility and other disorders of the reproductive system;\n3. taking part in all diagnostic and control tests to assess selected biological, functional and psychological parameters at indicated time points: before and after each of the 8-week exercise program during the first 8 months of the study and once every 3 months during the following twelve months of the study\n4. declaration of availability to participate in exercise classes three times a week for the first 8 months of the program (attendance at least 80% is required);\n5. declaration of participation in classes at least once a week and self-completion of the exercise program to the required 150 minutes of physical activity per week, according to the written guidelines prepared by the instructor, for the next 12 months of the program;\n6. women can participate in the exercise program regardless of their level of fitness or exercise capacity, as well as the level of motor skills (based on the diagnostic exercise tests, the exercise program will be tailored to the individual needs and capabilities of a woman).\n\nExclusion Criteria for Pregnant and Nonpregnant Women:\n\n1. contraindications to increased physical effort or to any of the diagnostic or control tests;\n2. allergies to materials used during diagnostic and control tests (e.g. nickel present in steel plates of vaginal electrodes, disinfectants);\n3. other conditions that, according to the researchers, will threaten the health or safety of the participants or will significantly affect the quality of the collected data.",{"count":508,"type":21},600,[52],"Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior. Physically active pregnant women significantly less often suffer from, among others, gestational diabetes, excessive weight gain, lipids disorders, hypertension, preeclampsia, depressive symptoms, functional and structural disorders, including stress urinary incontinence, back pain or diastasis recti abdominis (DRA). Prenatal physical activity reduces the risk of premature delivery and miscarriage, fetal macrosomia, complications in labor or the risk of metabolic disorders in children.\n\nHigh-intensity interval training (HIIT) has become one of the most popular trends in the fitness sector. The effectiveness of HIIT on a number of health indicators has been proven in various populations but limited data are available on HIIT during pregnancy.\n\nThe first hypothesis is that the HIIT, implemented during pregnancy and after childbirth, as a stronger exercise stimulus, will have a better impact on selected biological and psychological parameters of mothers, as well as on selected health parameters of their children, compared to the MICT (moderate intensity continuous training). Therefore, it promises better preventive effects on pregnancy complications and ailments as well as non-communicable diseases occurring in these populations. In the second hypothesis, it was assumed that HIIT and MICT implemented during pregnancy and after childbirth, tailored to the specific needs of the perinatal period, will not differ in the effectiveness of maintaining normal functional parameters in women, including prevention of urinary incontinence, back pain, DRA, etc.\n\nPregnant women who apply for the study will be divided into three groups: those attending the HIIT, MICT or educational programs. During the study, the participants will be under standard obstetric care. As comparative groups, non-pregnant women will be also recruited.\n\nThe investigators will collect data on selected biological, functional and psychological parameters in the study women at each trimester of pregnancy, during the puerperium and one year after childbirth. The data from the medical documentation on the course of childbirth and the assessment of the new-born, as well as the results of preventive examinations in the study women's children aged one, two, four and six years will be also analyzed.",[111,512,513,514,515,516,517,518,519,520,521,522,523,27,108,524,525,526],"Postpartum","Childbirth","Health Status","Physical Fitness","Noncommunicable Diseases","Metabolism","Diabetes Mellitus, Gestational","Pregnancy Induced Hypertension","Body Composition","Back Pain","Pain Threshold","Biomechanics","Cognitive Function","Depression","Anxiety",[528,529,530,531,347,532,533,534,535,536,537,514,538,513,539,540,541],"Pregnant women","Prenatal care","Postpartum women","Postnatal care","Physical activity","Exercise intervention","Educational intervention","Exercise test","High-intensity interval training","Moderate-intensity continuous training","Physical fitness","Birth outcomes","Infant","Child","2022-11-30",{"date":544,"type":32},"2022-12-02",{"date":546,"type":32},"2021-06-24",{"date":548,"type":21},"2031-08-31",{"name":550,"class":39},"Gdansk University of Physical Education and Sport"]