[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"percutaneous-nephrolithotomy-pcnl\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:percutaneous-nephrolithotomy-pcnl":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100628157","erector-spinae-plane-block-for-percutaneous-nephrolithotomy-100628157",false,"NCT07457983","Erector Spinae Plane Block for Percutaneous Nephrolithotomy","Perioperative Efficacy of Erector Spinae Plane Block in Patients Undergoing Percutaneous Nephrolithotomy","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* American Society of Anesthesiologists (ASA) physical status I-II.\n* Scheduled for elective percutaneous nephrolithotomy under general anesthesia.\n* Able to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years.\n* ASA physical status III-IV.\n* Refusal to participate in the study.\n* Known allergy or contraindication to local anesthetics (bupivacaine), opioids, or study medications.\n* Coagulopathy or anticoagulant therapy contraindicating regional block.\n* Infection at the injection site.\n* Severe psychiatric or cognitive disorder precluding reliable pain assessment or questionnaire completion.","ALL","18 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","Percutaneous nephrolithotomy (PCNL) is an effective standard urological procedure for the fragmentation and removal of large renal calculi. Although PCNL is performed as a minimally invasive technique, dilation of the renal capsule and parenchymal tract, as well as peritubular distension caused by the nephrostomy tube, may result in severe postoperative pain. Various analgesic strategies have been described in the literature for postoperative pain management following PCNL. These include systemic opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and several regional analgesia techniques. However, due to their adverse effect profiles, opioids and NSAIDs are not ideal options, particularly in patients with renal dysfunction. Regional techniques that have been utilized include local infiltration, intercostal nerve blocks, paravertebral blocks, and epidural analgesia.\n\nThe kidney is primarily innervated between the T10 and L1 segments, whereas the ureter receives innervation from T10 to L2. Based on this anatomical knowledge, unilateral regional blockade between T10 and L2 can provide adequate analgesia for PCNL procedures. Thoracic paravertebral block was previously a commonly preferred technique; however, it may be associated with complications such as intravascular injection, unintended epidural or intrathecal spread, and pneumothorax during its performance. In recent years, the number of reports describing the use of the erector spinae plane block (ESPB) as part of multimodal anesthesia for postoperative analgesia has increased. In ESPB, local anesthetic is injected into the interfascial plane between the transverse process of the vertebra and the erector spinae muscles, and has been reported to spread to multiple paravertebral spaces. ESPB is considered a peri-paravertebral block that can affect both visceral and somatic pain pathways.\n\nThe aim of this study is to evaluate the effect of ultrasound-guided erector spinae plane block on intraoperative and postoperative opioid consumption, postoperative pain scores, and quality of recovery in patients undergoing percutaneous nephrolithotomy.",[26,27,28],"Percutaneous Nephrolithotomy (PCNL)","Nephrolithiasis","Renal Calculi",[30,31,32,33,34],"Percutaneous Nephrolithotomy","Erector spinae plane block","Opioid consumption","Numerical pain scores (NRS)","Recovery quality (QoR-15T)","NOT_YET_RECRUITING","2026-03-09",{"date":38,"type":39},"2026-03-11","ACTUAL",{"date":41,"type":20},"2026-04-01",{"date":43,"type":20},"2026-06-01",{"name":45,"class":46},"Fadime Tosun","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":58,"conditions":59,"keywords":64,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":78},"100603619","hemodynamic-effects-of-surgical-position-in-prone-vs-supine-percutaneous-nephrolithotomy-100603619","NCT07138872","Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy","The Effect of Surgical Position on Hemodynamics in Percutaneous Nephrolithotomy Performed in Prone and Supine Positions","Inclusion Criteria:\n\n* ASA physical status I-III\n* Presence of renal calculi indicated for PNL\n\nExclusion Criteria:\n\n* Pregnancy\n* Uncontrolled coagulopathy\n* Previous renal surgery\n* Severe cardiac, pulmonary, or neurological disease\n* Preoperative urinary tract infection (non-sterile urine culture)\n* Surgery duration \\\u003C60 minutes or \\>120 minutes\n* Preoperative blood transfusion\n* Multiple access tracts","80 Years",{"count":56,"type":20},84,[23],"This prospective, randomized controlled study evaluates the hemodynamic effects of prone and supine positions during percutaneous nephrolithotomy (PNL) for large kidney stones. Surgical position may influence intraoperative and postoperative hemodynamic stability. Prone positioning can increase intrathoracic pressure and reduce venous return, whereas supine positioning may provide greater hemodynamic stability. A total of 84 patients will be randomized to undergo PNL in prone or supine positions. Primary outcomes include changes in hemodynamic parameters during surgery. Results may guide surgical position selection, especially in patients with potential hemodynamic risk.",[26,60,61,62,63,27],"Surgical Positioning","Prone Position","Supine Position","Hemodynamic Stability",[65,61,30,62,66,27],"PCNL","Hemodynamic stability","RECRUITING","2025-08-16",{"date":70,"type":39},"2025-08-24",{"date":72,"type":39},"2025-06-01",{"date":74,"type":20},"2025-12-30",{"name":76,"class":77},"Gaziosmanpasa Research and Education Hospital","OTHER_GOV",1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":21,"phases":89,"briefSummary":90,"conditions":91,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":4},"100587947","erector-spinae-block-vs-conventional-analgesia-for-postoperative-analgesia-in-pcnl-100587947","NCT06935006","Erector Spinae Block vs Conventional Analgesia for Postoperative Analgesia in PCNL","Sonographic Guided Erector Spinae Plane Block Versus Conventional Analgesia After Percutaneous Nephrolithotomy a Comparative Randomized Study","Inclusion Criteria:\n\n* ASA 1 to ASA 2 18 to 60 years\n\nExclusion Criteria:\n\n* patient refusal Significant neurological , psychiatric or neuromascular disease Drug abuse Pregnant or lactating women Suspected coagulopathy Morbid obesity Known allergy to some medications Septicaemia and local infection at block site","60 Years",{"count":88,"type":20},50,[23],"50 adult patients scheduled for percutaneous nephrolithotomy in Sohag university hospitals will be devided in two groups one of them will receive Sonographic guided erector spinae plane block using 20 ml volume of bupivacaine 0.25 percent and the other will receive conventional analgesia of 0.1 mg\u002Fkg IV morphine",[26],"2025-04-11",{"date":94,"type":39},"2025-04-18",{"date":96,"type":20},"2025-05-01",{"date":98,"type":20},"2026-05-01",{"name":100,"class":46},"Sohag University"]