[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"perfusion-index\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:perfusion-index":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,44,72,100,123,149,174,196],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100054261","ai-guided-predictions-of-blood-pressure-dysregulation-using-perfusion-index-as-a-novel-biomarker-in-persons-with-spinal-cord-injury-100054261",false,"NCT07699094","AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury","Inclusion Criteria:\n\n* You have had a spinal cord injury (SCI: C4-T12) for more than one year and the SCI was graded as ASIA Impairment Scale (AIS) A or B (unable to voluntarily move your legs)\n* You can also be a gender and age-matched (±5 years) able-bodied (AB) control subject (similar gender and age to a subject with SCI).\n* Subjects with SCI and AB controls must be between 18 and 75 years of age.\n* If you are going to participate, you must avoid caffeine and alcohol, maintain normal salt and water intake, and avoid strenuous exercise for 24 hours prior to the study visit.\n\nExclusion Criteria:\n\n* You have cardiovascular, kidney, or untreated thyroid disease\n* You have a traumatic brain injury (TBI)\n* You have diabetes mellitus\n* You have an acute illness or infection\n* You are dehydrated\n* You smoke\n* You are pregnant\n* You have broken, inflamed, or otherwise fragile skin\n* Your Body Mass Index (BMI) is more than 30 kg\u002Fm2",true,"ALL","18 Years","75 Years",{"count":20,"type":21},24,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to determine if perfusion index (PI) can reliably predict changes in systolic blood pressure (SBP) in persons with spinal cord injury (SCI) during a cool temperature challenge. Participants with SCI can be 18-75 years of age, male or female, neurological level of injury C4-T12, ASIA Impairment Scale (AIS: A or B: motor complete) or gender and healthy age-matched able-bodied (AB) controls.\n\nThe main question this study aims to answer is: can PI reliably predict change in SBP during a cool temperature challenge? We hypothesize that PI can be used as a biomarker of SBP in persons with SCI.\n\nResearchers will compare the relationship of 1) changes in PI and SBP and 2) relationship of changes in other vital signs to SBP, during the cool temperature challenge. The researchers aim to determine if PI can be used as a biomarker of SBP in persons with SCI during a cool temperature challenge (experimental group\u002Farm). Able-bodied controls (control group\u002Farm) will receive the same intervention (cool challenge) as the experimental group.\n\nDuring the study, participants will be asked to wear only shorts and a T-shirt so that their skin can be exposed to the warm and cool temperatures of the 2 rooms.\n\nWe will put put on non-invasive sensors (taped or attached on the surface of your body) to measure PI, BP, and other vital signs. We will record these measurements while you are seated in a wheelchair for 10 minutes in a warm room and up to 90 minutes in a cool room.",[27,28,29,30],"Spinal Cord Injuries (SCI)","Blood Pressure","Thermoregulation","Perfusion Index","RECRUITING","2026-07-07",{"date":34,"type":35},"2026-07-13","ACTUAL",{"date":37,"type":21},"2026-07-01",{"date":39,"type":21},"2028-06-30",{"name":41,"class":42},"James J. Peters Veterans Affairs Medical Center","FED",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":4},"100643126","comparison-of-90-and-120-arm-positions-in-costoclavicular-block-100643126","NCT07586670","Comparison of 90° and 120° Arm Positions in Costoclavicular Block","Effect of Arm Abduction Degree ( 90° vs. 120° ) on Block Onset Time and Block Success in Costoclavicular Brachial Plexus Block in Patients Undergoing Hand, Wrist and Forearm Surgery: A Prospective Randomized Controlled Trial","COSTO-RCT","Inclusion Criteria:\n\n* Patients aged between 18 and 80 years.\n* Patients scheduled for elective upper extremity surgery (hand, wrist, forearm).\n* Patients classified as ASA I-III.\n* Patients who provide informed consent after being informed about the study.\n\nExclusion Criteria:\n\n* History of previous surgery, scar tissue, tumor, or trauma that may alter brachial plexus anatomy.\n* Presence of infection, hematoma, severe edema, burn, or open wound at the block application site.\n* Known allergy to local anesthetics or other medications used in the study.\n* Coagulopathy, use of anticoagulants, or platelet count \\\u003C 100,000\u002Fmm³.\n* History of peripheral neuropathy, neurological deficit, cervical radiculopathy, or CRPS.\n* Pregnancy or breastfeeding.\n* Patients with BMI \\\u003C 18 kg\u002Fm².\n* Patients with BMI \\> 35 kg\u002Fm².\n* Severe cardiac, pulmonary, renal, or hepatic failure.\n* Mental retardation, communication difficulties, or lack of cooperation.\n* Deformity, amputation, or large mass in the surgical extremity that may interfere with sensorimotor assessment.\n* Preoperative significant sensory loss, motor weakness, or signs of neurological disease.\n* Severe anemia (Hb \\\u003C 9 g\u002FdL) or polycythemia (Hb \\> 18 g\u002FdL).\n* Psychiatric disorders, substance abuse, or any condition that may interfere with study compliance.","80 Years",{"count":54,"type":21},106,[24],"The costoclavicular approach of the infraclavicular brachial plexus block is widely used for upper extremity surgeries due to its reliable anatomy and high success rates. Patient positioning, particularly the degree of arm abduction, may influence the spread of local anesthetic and the characteristics of the block. However, the optimal arm abduction angle during this procedure remains unclear.\n\nThis prospective randomized controlled trial aims to investigate the effect of two different arm abduction angles (90° and 120°) on block onset time and block success in patients undergoing hand, wrist, and forearm surgery under ultrasound-guided costoclavicular brachial plexus block.\n\nPatients will be randomly assigned to one of two groups according to the degree of arm abduction. The primary outcome is block onset time. Secondary outcomes include block success, sensory and motor block characteristics, perfusion index changes, hemodynamic parameters, readiness for surgery at 15 and 20 minutes, block performance time, need for additional anesthesia, postoperative neurological evaluation at 4 and 24 hours, complications, and patient satisfaction.\n\nThe findings of this study are expected to provide evidence on optimal patient positioning to improve the effectiveness and reliability of ultrasound-guided costoclavicular brachial plexus block.",[30,58,59,60],"Upper Extremity Surgery","Brachial Plexus Block","Regional Anaesthesia","NOT_YET_RECRUITING","2026-06-06",{"date":64,"type":35},"2026-06-09",{"date":66,"type":21},"2026-05-15",{"date":68,"type":21},"2026-08-27",{"name":70,"class":71},"Ankara Etlik City Hospital","OTHER_GOV",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":43},"100623711","evaluation-of-the-effects-of-changes-in-operating-table-position-on-perfusion-index-and-spinal-anesthesia-100623711","NCT07400185","Evaluation Of The Effects Of Changes In Operating Table Position On Perfusion Index And Spinal Anesthesia","Evaluation Of The Effects Of Changes In Operating Table Position On Perfusion Index And Spinal Anesthesia: An Observational Study","Perfusion","Inclusion Criteria:\n\n* Patients who will undergo lower extremity surgery within the specified time frame, are in ASA 1-3 risk group, have no additional medical conditions, and will receive spinal anesthesia.\n\nExclusion Criteria:\n\n* Patients under 18 and over 65 years of age Patients who have received anesthesia other than spinal anesthesia Patients with peripheral artery disease Patients with nail polish, etc. on their nails","65 Years",{"count":82,"type":21},150,"OBSERVATIONAL","The aim of this observational study is to investigate how table position affects the development of block in patients undergoing spinal anesthesia. Perfusion index measurements will be used to answer this question. Patients who will undergo perfusion index measurement during surgery will be included in the study. These patients will be compared with patients whose anesthesiologists chose not to position them on the operating table. The study is planned to continue for approximately 40 days, and the data collected during this period will be used for evaluation.",[30,86],"Position Differences",[88,89],"The Effects of Changes in Operating Table Position on Perfusion Index and Spinal Anesthesia","operating table position","2026-02-09",{"date":92,"type":35},"2026-02-11",{"date":94,"type":21},"2026-02-05",{"date":96,"type":21},"2026-04-20",{"name":98,"class":99},"Enes Celik","OTHER",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":107,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":4},"100608109","perfusion-index-and-end-diastolic-velocity-ratios-as-predictors-of-supraclavicular-block-success-in-vascular-access-surgery-100608109","NCT07197281","Perfusion Index and End Diastolic Velocity Ratios as Predictors of Supraclavicular Block Success in Vascular Access Surgery","Correlation Between Perfusion Index Ratio and End Diastolic Velocity Ratio After Supraclavicular Brachial Plexus Block as an Early Predictor of Successful Block in Superficialization Surgery of the Upper Limb","Inclusion Criteria:\n\n* Adults aged 18-65 years\n\nBoth genders\n\nASA II-VI classification\n\nUndergoing elective upper limb superficialization surgery (e.g., AVF superficialization)\n\nProvided written informed consent\n\nExclusion Criteria:\n\n* Patient refusal\n\nCoagulopathy or bleeding disorders\n\nLocal infection at injection site\n\nAllergy to local anesthetics\n\nUse of vasopressors or beta-blockers\n\nSevere peripheral vascular disease\n\nMorbid obesity (BMI \\> 35)\n\nSevere neurological or psychiatric disorders",{"count":108,"type":21},50,"This is a prospective observational study investigating the correlation between Perfusion Index (PI) ratio and End Diastolic Velocity (EDV) ratio as early predictors of successful supraclavicular brachial plexus block (SCBPB) in patients undergoing superficialization surgery of the upper limb.",[111,30],"End Diastolic Velocity",[111,113,30],"brachial plexus block","2025-09-20",{"date":116,"type":35},"2025-09-29",{"date":118,"type":21},"2026-05-01",{"date":120,"type":21},"2027-12-30",{"name":122,"class":99},"Assiut University",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":130,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":132,"conditions":133,"keywords":136,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":43},"100602220","ppi-in-weaning-prediction-100602220","NCT07120672","PPI in Weaning Prediction","The Role of Peripheral Perfusion Index as a Predictive Factor During Weaning Process","Inclusion Criteria:\n\n* Patients who have been on mechanical ventilation for at least 48 hours\n* Patients over 18 years of age who are planned to undergo extubation following a spontaneous breathing trial (SBT)\n* Patients or their legal representatives who provide informed consent to participate in the study\n\nExclusion Criteria:\n\n* Patients for whom extubation is not planned due to hemodynamic instability\n* Patients with peripheral vascular disease or a history of hand surgery\n* Patients who die or cannot be followed up during the study period",{"count":131,"type":21},100,"The aim of this study is to evaluate the predictive role of the Peripheral Perfusion Index (PPI) in forecasting extubation success during the weaning process in intensive care unit (ICU) patients. The study will investigate the ability of PPI to predict extubation failure by comparing it with traditional weaning criteria, including the Rapid Shallow Breathing Index (RSBI), PaO₂\u002FFiO₂ ratio, and respiratory rate.",[30,134,135],"Weaning of Mechanical Ventilation","ICU",[137,138,139],"perfusion index","weaning","ıcu","2025-08-06",{"date":142,"type":35},"2025-08-13",{"date":144,"type":35},"2025-05-08",{"date":146,"type":21},"2025-08-30",{"name":148,"class":71},"Gaziosmanpasa Research and Education Hospital",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":16,"minAge":156,"maxAge":157,"enrollmentInfo":158,"targetDuration":4,"studyType":22,"phases":160,"briefSummary":161,"conditions":162,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":43},"100590458","perfusion-index-in-pediatric-low-flow-anesthesia-100590458","NCT06967675","Perfusion Index in Pediatric Low-Flow Anesthesia","Changes in Perfusion Index Under Low-Flow Anesthesia and Its Effects on Postoperative Emergence in Pediatric Patients","Inclusion Criteria:\n\n* ASA I-II pediatric patients\n* Age 2 to 12 years\n* Undergoing elective surgery lasting between 1-6 hours\n* Informed consent obtained from parents\u002Fguardians\n\nExclusion Criteria:\n\n* Cardiovascular, respiratory, neurological, metabolic, or endocrine disorders\n* Premature birth with corrected age \\\u003C 2 years\n* Obesity or severe malnutrition (BMI \\\u003C5th or \\>95th percentile)\n* Psychiatric or neurodevelopmental disorders (e.g., autism)\n* Malignant hyperthermia or hypersensitivity to anesthetics\n* Emergency surgeries\n* Lack of IV access requiring inhalational induction\n* Contraindications to low-flow anesthesia including:\n* Severe pulmonary disease\n* Congenital heart disease with shunt physiology\n* Anticipated high oxygen demand\n* Airway obstruction risk\n* Surgeries requiring high gas flow or \\>6 hours duration","2 Years","12 Years",{"count":159,"type":21},90,[24],"This study aims to evaluate changes in perfusion index (PI) in pediatric patients undergoing elective surgery under low-flow anesthesia. PI will be monitored at multiple intraoperative and postoperative time points to assess its relationship with hemodynamic stability and depth of anesthesia. The study will also investigate whether low-flow anesthesia affects the incidence of emergence agitation (EA). Patients will be assigned to either low-flow or normal-flow anesthesia groups based on routine clinical practice. No intervention will be applied beyond standard care. The findings are expected to provide insight into the predictive value of PI in postoperative recovery and support safer anesthesia practices in pediatric populations.",[30,163,164],"Low-Flow Anesthesia","Postoperative Recovery","2025-07-08",{"date":167,"type":35},"2025-07-10",{"date":169,"type":35},"2025-06-15",{"date":171,"type":21},"2025-08-10",{"name":173,"class":99},"Istinye University",{"id":175,"slug":176,"hasResults":11,"nctId":177,"briefTitle":178,"officialTitle":179,"acronym":4,"eligibilityCriteria":180,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":181,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":183,"conditions":184,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":43},"100582217","observational-study-about-the-use-of-perfusion-index-to-use-vasopressor-in-sepsis-100582217","NCT06860438","Observational Study About the Use of Perfusion Index to Use Vasopressor in Sepsis","Can Perfusion Index Indicate the Need of Vasopressor in ICU Patients with Sepsis and Septic Shock, Prospective Observational Study","Inclusion Criteria:\n\n\\- All ICU patients with clinically suspected sepsis and septic shock ( signs include fever hypotension oliguria and confusion combined with culture results showing infection .Septic shock is a subset of sepsis involves persistent hypotension (mean arterial pressure ≥ 65 mm Hg, and a serum lactate level \\> 18 mg\u002FdL \\[2 mmol\u002FL)not responding to fluid resuscitation ) .\n\nExclusion Criteria:\n\n* Pregnant females\n* Patients on vasopressor or positive inotropic drugs\n* Patients with hypothermia (defined as central temperature \\\u003C35°C).\n* Patient with impairment of upper extremity circulation,(such as those who underwent radial artery harvesting for coronary artery bypass grafting or had suspected occlusion of the radial artery prior to surgery,)\n* Patients had undergone an operation that involved the large arteries of the aortic arch.\n* Patients with atherosclerosis .",{"count":182,"type":21},40,"In this thesis we will use the current state of knowledge that PI can provide a reliable information about the state of peripheral microcirculation during the state of sepsis and septic shock in ICU patients and that can interfere with the timing of starting vasopressor treatment in sepsis and septic shock",[185,30,186],"Sepsis","Vasopressor","2025-03-03",{"date":189,"type":35},"2025-03-06",{"date":191,"type":35},"2024-08-01",{"date":193,"type":21},"2025-03",{"name":195,"class":99},"Ain Shams University",{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":200,"acronym":201,"eligibilityCriteria":202,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":203,"targetDuration":4,"studyType":22,"phases":204,"briefSummary":205,"conditions":206,"keywords":207,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":218,"locationsCount":4},"100564210","comparison-of-perfusion-index-monitoring-using-a-smartwatch-and-a-pulse-oximeter-100564210","NCT06626217","Comparison of Perfusion Index Monitoring Using a Smartwatch and a Pulse Oximeter","PIWATCH","Inclusion Criteria:\n\n* Healthy Adult Volunteer\n\nExclusion Criteria:\n\n* Post-traumatic upper limb conditions affecting finger or arm perfusion\n* Injuries or diseases of the skin of the fingers and arm\n* Any acute phase of any disease",{"count":108,"type":21},[24],"The aim of the study is to experimentally compare measured perfusion index values between smartwatch and a medical grade pulse oximeter in healthy subjects at rest and with and without motion artifacts and during exercise.",[30],[208,209,210,211],"Pulse oximetry","Perfusion index","Finger replantation","Smartwatch","2024-10-01",{"date":214,"type":35},"2024-10-03",{"date":216,"type":21},"2024-10-08",{"date":146,"type":21},{"name":219,"class":99},"Czech Technical University in Prague"]