[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"peri-prosthetic-joint-infection\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:peri-prosthetic-joint-infection":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100572787","ip-coated-revision-hip-implants-100572787",false,"NCT06737809","IP-coated Revision Hip Implants","HIPrevision - A Randomized Multicenter Clinical Investigation of Antimicrobial IP-Coated Revision Hip Prostheses","HIPrevision","Inclusion Criteria:\n\n* Patients \\> 18 years\n* Patients indicated for unilateral cementless acetabular and hip stem revision due to chronic periprosthetic infection (according to EBJIS definition): single-stage or two-stage surgical procedure according to clinical standard at the clinical investigation site\n* According to the assessment of the clinical investigator, the subject is therapy compliant and able to attend the follow-up visits\n* ASA physical status I - III\n* Patient's signed written informed consent is available\n\nExclusion Criteria:\n\n* Simultaneous participation in another interventional clinical trial (drugs or medical devices studies)\n* The investigational implant components (femoral and\u002For acetabular) are not suitable for the patient anatomy or bone defect\n* Patients who require plate osteosynthesis at the implantation site\n* Patients with an already implanted silver-coated device\n* Patients with immunodeficiency, i.e. patients currently receiving immunosuppressive therapy or patients with severe immunodeficiency requiring drug therapy\n* Patients currently undergoing cancer treatment, e.g. chemotherapy or radiation therapy\n* Severe soft tissue defects that require local or free flap procedure\n* Periprosthetic joint infections with evidence of fungal infection\n* Antibiotic suppression therapy\n* BMI \\> 40 kg\u002Fm2\n* Pregnancy, breast-feeding, or women of childbearing potential and not taking adequate contraceptive precautions\n* Known or patient reported hypersensitivity to silver or titanium\n* Patients held in a custodial setting\n* Patients in a relationship of dependence on the sponsor, the clinic or the investigator\n* Patients with contraindication for the investigational and comparator devices:\n* in case of secondary diseases influencing the function of the joint implant\n* in case of severe osteoporosis or osteomalacia\n* in case of poor bone quality and osseous malformations, diseases in the area of the implant fixation, which may primarily or subsequently affect the stability of the joint replacement anchorage\n* in case of non-regenerative bone conditions with lack of proximal femoral bone support and failure of defect union when use of prosthesis heads with neck length XXL is indicated","ALL","18 Years",{"count":20,"type":21},268,"ESTIMATED","INTERVENTIONAL",[24],"NA","The primary aim of the clinical investigation is to demonstrate the efficacy of a silver-based antimicrobial coating on hip implants in the reduction of periprosthetic infections in revision hip arthroplasty due to periprosthetic infection.",[27],"Peri-Prosthetic Joint Infection",[29,30,31,32,33,34],"arthroplasty","replacement","hip","anti-infective agent","silver","periprosthetic joint infection","RECRUITING","2026-01-09",{"date":38,"type":39},"2026-01-12","ACTUAL",{"date":41,"type":39},"2025-06-25",{"date":43,"type":21},"2028-06",{"name":45,"class":46},"Aesculap AG","INDUSTRY",2]