[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"peridontal-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:peridontal-disease":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,52,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100583917","phase-3-efficacy-of-resveratrol-containing-mouthwash-in-reducing-halitosis-related-porphyrymonas-gingivalis-100583917",false,"NCT06882564","Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.","Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyromonas Gingivalis: A Randomized, Triple-blind Clinical Trial","Inclusion Criteria:\n\n* Organoleptic tongue of scores \\> 2 using (0-5scale) (Rosenberg and McCulloch, 1992)\n* Male and female undergraduate dental students without chemical plaque control measures for at least one weak\n* Male and female students with halitosis due to gingivitis\n* The age of students ranges from 20 to 23 years.\n* No periodontal treatment for at least one month\n* No systemic disease\n* No tobacco smoking\n* The patients must have at least 20 teeth\n\nExclusion Criteria:\n\n* Smokers and alcoholics\n* Patient with periodontitis or pocket depth \\> 6mm\n* Patient with orthodontics appliance\n* Open carious lesions, pericoronitis, dry socket, and fistula.\n* Patients with systemic disease and condition\n* taking medication in the last two weeks\n* Take garlic, onion, or licorice in the last 24 hours\n* using oral hygiene products in the last 24 hours\n* pregnant women\n* sinusitis, tonsilitis, and upper respiratory tract infection",true,"ALL","20 Years","24 Years",{"count":21,"type":22},54,"ESTIMATED","INTERVENTIONAL",[25],"PHASE3","The aim of the study:\n\nTo assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah University\u002FCollege of Dentistry and Wasit University \u002FCollege of Dentistry.\n\nObjectives:\n\n* To assess the efficacy of anti-oxidant and anti-inflammatory resveratrol mouthwash in reducing halitosis in undergraduate students with plaque-induced gingivitis patients.\n* To assess the efficacy of resveratrol mouthwash in reducing p. gingivalis in undergraduate students' patients with oral malodor.\n* To determine the relation between p.gingivalis and clinical periodontal parameters (plaque index, gingival index, bleeding on probing) among undergraduate students with plaque-induced gingivitis and halitosis.",[28,29,30,31,32],"Halitosis","Mouth Disease","Plaque Induced Gingival Disease","Bleeding Gum","Peridontal Disease",[34,35,36,37,38],"halitosis","plaque","gingivitis","resveratrol","chlorhexidine","RECRUITING","2025-03-16",{"date":42,"type":43},"2025-03-18","ACTUAL",{"date":45,"type":43},"2025-01-05",{"date":47,"type":22},"2025-11-01",{"name":49,"class":50},"Al-Mustansiriyah University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":23,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":51},"100578213","the-effect-of-hypnosis-on-periodontal-treatment-100578213","NCT06808373","The Effect of Hypnosis on Periodontal Treatment","The Effect of Hypnosis on Healing in Patients Undergoing Phase I Periodontal Therapy","Inclusion Criteria:\n\nBeing between the ages of 20-65 Not having any systemic disease Having chronic periodontal disease Having the ability to understand the study and answer questions\n\nExclusion Criteria:\n\nHaving any systemic disease Being under 20 or over 65 Not having any periodontal disease","65 Years",{"count":61,"type":22},50,[63],"NA","Treatment of periodontal diseases relies on the mechanical removal of microbial dental plaque, calculus, and necrotic cementum from root surfaces in both supra- and subgingival areas to control inflammation in periodontal tissues. As in all dental treatments, dental phobia and dental anxiety are common challenges in initial periodontal therapy. Hypnosis is among the traditional non-pharmacological behavior management techniques used to manage stress and improve pain tolerance. It is known that hypnosis is effective in anxiety control in dentistry. The use of salivary levels of inflammatory mediators released during the disease is a valid method for assessing the progression of periodontal disease and healing after treatment. In this study, the effect of hypnosis on healing in patients undergoing Phase I periodontal therapy will be evaluated by comparing the mean differences in cytokine levels between case and control groups",[32,66],"Dental Anxiety",[68],"periodontitis, hypnosis, dental anxiety","2025-01-30",{"date":71,"type":43},"2025-02-05",{"date":73,"type":43},"2024-11-18",{"date":75,"type":22},"2026-11-18",{"name":77,"class":50},"Afyonkarahisar Health Sciences University",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":17,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":23,"phases":88,"briefSummary":89,"conditions":90,"keywords":91,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":103},"100576758","assessment-of-pro-resolution-mediator-levels-in-periodontitis-stage-iii-and-iv-before-and-after-periodontal-therapy-100576758","NCT06789458","Assessment of Pro-Resolution Mediator Levels in Periodontitis Stage III and IV Before and After Periodontal Therapy","Inclusion Criteria:\n\nInclusion criteria:\n\n1. Adult patients above 18 years old.\n2. Interdental CAL at site of greatest loss ≥5 mm or extending to middle third of the root.\n3. Interdental CAL at site of greatest loss ≥8 mm or extending to apical third of the root.\n4. Probing depth ≥6 mm.\n5. Vertical bone loss ≥3 mm.\n6. Tooth loss due to periodontitis of ≤4 teeth. (Periodontitis Stage III)\n7. Tooth loss due to periodontitis of ≥5 teeth. (Periodontitis Stage IV)\n8. Furcation involvement Class II or III Moderate ridge defect.\n\n   \\-\n\nExclusion Criteria:\n\n* 1\\. Pregnancy or lactation. 2. Smoking more than 20 cigarettes. 3. Immuno-inflammatory conditions of the skin and oral mucosa 4. systemic conditions affecting bone turnover and periodontal health status (e.g. endocrine and connective tissue diseases, bisphosphonate antiresorptive therapy, gastrointestinal diseases related to nutrition and mineral metabolism) 5. Periodontal or orthodontic treatment at least 6 months before the start of the study 6. Use of anti-inflammatory and antimicrobial agents within 3 months before sampling\n\nInclusion criteria for healthy group:\n\n1. Systemically healthy patients.\n2. Patients with an age range between 16 to 80 years.\n3. Patients have a minimum of 20 teeth.\n4. Less than 10% bleeding sites with probing depths ≤3 mm.\n5. absence of erythema, oedema.","18 Years","80 Years",{"count":87,"type":22},22,[63],"This study aims to assess Pro-Resolution Mediator levels during non-surgical periodontal therapy in individuals with Stage III and IV periodontitis, comparing them to healthy subjects. Periodontitis, a chronic inflammatory condition affecting tooth-supporting tissues, can lead to tooth loss and systemic complications. Understanding the role of pro-resolving lipid mediators in inflammation resolution may offer insights into therapeutic benefits associated with these mediators.",[32],[92,93],"lipoxin","proresolution mediators","2025-01-17",{"date":96,"type":43},"2025-01-23",{"date":98,"type":43},"2022-10-15",{"date":100,"type":22},"2025-10-14",{"name":102,"class":50},"Cairo University",2]