[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"perimenopausal-depression\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:perimenopausal-depression":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,51,85,118],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":4},"100643860","multidimensional-determinants-of-functional-health-in-women-aged-45-60-100643860",false,"NCT07667699","Multidimensional Determinants of Functional Health In Women Aged 45-60","Multidimensional Determinants and Structural Foundations of Functional Health In Women Aged 45-60: The Role of Muscle and Bone Health","Inclusion Criteria are:\n\n* Women aged 45 to 60 years\n* Ability to read and complete study questionnaires\n* Provision of written informed consent\n* Ability to complete physical performance assessments\n\nExclusion Criteria are:\n\n* Acute systemic illness\n* Active malignancy\n* Severe neurological or orthopedic impairment limiting physical performance assessment\n* Cognitive impairment precluding informed consent or questionnaire completion",true,"FEMALE","45 Years","60 Years",{"count":21,"type":22},200,"ESTIMATED","1 Day","OBSERVATIONAL","The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years. The study will focus on the role of muscle strength, bone mineral density, body composition, physical activity, sleep quality, depressive symptoms, and menopause-related symptoms in functional health.\n\nThe main questions it aims to answer are:\n\n1. Does muscle strength contribute to functional health in women aged 45 to 60 years?\n2. Does bone mineral density contribute to functional health in women aged 45 to 60 years?\n3. How are physical activity, sleep quality, depressive symptoms, body composition, and menopause-related quality of life associated with functional health?\n\nParticipants will:\n\n* Undergo handgrip strength measurement\n* Perform a 30-second chair stand test\n* Undergo bone mineral density and body composition assessment\n* Complete questionnaires about physical activity, sleep quality, depressive symptoms, menopausal symptoms, and quality of life\n* Provide demographic and clinical information",[27,28,29,30,31,32,33],"Healthy","Perimenopausal Depression","Menopausal Complaints","Bone Mineral Density","Sarcopenia","Sleep Quality","Quality of Life",[35,36,37,31,32,38],"Menopause","Perimenopause","Bone mineral density","Quality of life","NOT_YET_RECRUITING","2026-06-19",{"date":42,"type":43},"2026-06-25","ACTUAL",{"date":45,"type":22},"2026-06-15",{"date":47,"type":22},"2026-12-31",{"name":49,"class":50},"Kartal City Hospital","OTHER",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100641801","meleis-transition-theory-based-education-and-counseling-program-in-menopausal-women-100641801","NCT07657078","Meleis' Transition Theory-Based Education and Counseling Program in Menopausal Women","The Effect of a Meleis' Transition Theory-Based Education and Counseling Program on Menopausal Symptoms, Perimenopausal Depression, and Menopause-Specific Quality of Life in Menopausal Women: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Female participants aged 45 to 55 years\n* Naturally menopausal women\n* Menopause duration not exceeding 2 years\n* Experiencing menopausal symptoms\n* Sexually active\n* Able to read and write Turkish\n* Willing to participate voluntarily\n* Able to provide written informed consent\n* Not currently receiving hormone replacement therapy\n* No history of psychiatric disorders\n* No previous menopause-related education\n\nExclusion Criteria:\n\n* Failure to continue participation in the study\n* Failure to attend education and counseling sessions\n* Withdrawal from the study at any time\n* Withdrawal of informed consent\n* Loss to follow-up","55 Years",{"count":60,"type":22},114,"INTERVENTIONAL",[63],"NA","This randomized controlled trial aims to evaluate the effectiveness of a Meleis' Transition Theory-based education and counseling program on menopausal symptoms, perimenopausal depression, and menopause-specific quality of life among naturally menopausal women aged 45 to 55 years.\n\nParticipants will be randomly assigned to either the intervention group or the control group. The intervention group will receive a structured four-week education and counseling program based on Meleis' Transition Theory, supported by a secure online messaging group and follow-up counseling sessions. The control group will receive routine care and standard information during the study period and will be offered a one-day educational session after completion of the final assessment.\n\nThe outcomes will be measured at baseline and Week 16 using the Menopause Rating Scale, the Perimenopausal Depression Scale, and the Menopause-Specific Quality of Life Questionnaire-II.",[35,66,28],"Menopausal Symptoms",[35,68,69,70,71,72,73,38,74,75],"Menopausal transition","Meleis' Transition Theory","Education","Counseling","Menopausal symptoms","Perimenopausal depression","Women's health","Nursing","2026-06-17",{"date":78,"type":43},"2026-06-22",{"date":45,"type":22},{"date":81,"type":22},"2026-10-15",{"name":83,"class":50},"Ankara Medipol University",1,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":61,"phases":94,"briefSummary":95,"conditions":96,"keywords":101,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":84},"100633931","the-effect-of-cold-packs-on-hot-flushes-and-depression-in-women-going-through-the-climacteric-period-100633931","NCT07533097","The Effect of Cold Packs on Hot Flushes and Depression in Women Going Through the Climacteric Period","The Effect of Applying Cold Gel Packs to the LI4 and SP6 Acupoints on Menopausal Hot Flashes and Depression in Women During the Climacteric Period","Inclusion Criteria:\n\n* In the perimenopausal phase (no menstruation for 3-11 months or an increase in irregular menstrual bleeding) or the postmenopausal phase (no menstruation for more than 12 months),\n* Participants experiencing moderate to severe hot flushes at least four times a day in the week prior to enrolment,\n* Participants who are literate in Turkish and able to communicate,\n* Participants who volunteer to take part in the study will be included in the study.\n\nExclusion Criteria:\n\n* Women who have entered menopause following surgery,\n* Women whose hot flush symptoms have decreased or ceased in the week prior to joining the study,\n* Those receiving hormone replacement therapy,\n* Those who had received herbal medication (such as black cohosh, black cohosh, ginkgo, ginseng, motherwort, valerian, black snake root, St. John's wort, etc.) or chemical medication for at least two weeks prior to joining the study,\n* Women with endocrine system disorders such as diabetes or a condition presenting symptoms similar to hot flushes,\n* Women with a regular menstrual cycle,\n* Women with a psychiatric diagnosis who are currently receiving treatment,\n* Women taking sleeping pills,\n* Women with a language barrier preventing communication in Turkish,\n* Women who are not willing to participate in the study will not be included in the research.",{"count":93,"type":22},80,[63],"This study is planned as a pre-post test, randomised controlled, experimental trial designed to determine the effect of applying a cold gel pack to the Sanyinjiao (SP6) and Hegu (Large Intestinal 4 (LI4)) acupoints on hot flushes and depression in women during the climacteric period.",[97,98,28,99,100],"Hot Flashes","Climactericum","Cold Application","Acupoints",[102,103,104,105,106,107,108],"Climacterium","hot flashes","perimenopausal depression","cold gel packs","cold application","LI4 acupoint","SP6 acupoint","2026-04-16",{"date":111,"type":43},"2026-04-21",{"date":113,"type":22},"2026-04-13",{"date":115,"type":22},"2026-09-13",{"name":117,"class":50},"Rabia Atilla",{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":17,"minAge":125,"maxAge":58,"enrollmentInfo":126,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":128,"conditions":129,"keywords":136,"overallStatus":142,"whyStopped":4,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":84},"100594705","a-trial-to-investigate-the-accuracy-of-a-wearable-device-in-collecting-data-related-to-perimenopausal-symptoms-in-women-100594705","NCT07022925","A Trial to Investigate the Accuracy of a Wearable Device in Collecting Data Related to Perimenopausal Symptoms in Women","An Observational Virtual Trial to Investigate the Accuracy of a Wearable Device in Collecting Data Related to Perimenopausal Symptoms in Women","Inclusion Criteria:\n\n1. Females between 35-55 years of age, inclusive\n2. Self-reported perimenopausal women experiencing hot flushes or night sweats\n3. Individuals of child-bearing potential must confirm they are not pregnant, do not plan to become pregnant, and agree to use a medically approved method of birth control for the duration of the study. Acceptable methods of birth control include:\n\n   * Double-barrier method\n   * Intrauterine devices\n   * Non-heterosexual lifestyle or agrees to use contraception if planning on changing to heterosexual partner(s)\n   * Vasectomy of partner at least 6 months prior to screening\n   * Abstinence\n4. Agrees to maintain current lifestyle as much as possible throughout the study, including diet, exercise, supplements\u002Fmedications, and sleep\n5. Provided voluntary and informed consent to participate in the study\n6. Generally healthy as determined by medical history with no unstable diagnosed medical conditions\n\nExclusion Criteria:\n\n1. Allergy or sensitivity to adhesive used for wearing the investigational device\n2. Self-reported use of a pacemaker\n3. Self-reported unstable diagnosed anxiety disorder\n4. Self-reported sleep disorder requiring medical treatment\n5. Self-reported skin conditions or sensitive skin around the area of application\n6. Self-reported surgery in the past three months or individuals who have planned surgery during the course of the study\n7. Alcohol intake average of ˃1 standard drink per day\n8. Alcohol or drug abuse within the last 12 months that has required treatment\n9. Current use of prescribed and\u002For over-the-counter (OTC) medications\u002Fsupplements that may impact data recorded by the investigational device (see Section 7.3)\n10. Participation in other clinical research studies 30 days prior to screening\n11. Individuals who are unable to give informed consent\n12. Any other condition or lifestyle factor, that may adversely affect the participant's ability to complete the study or its measures or pose significant risk to the participant","35 Years",{"count":127,"type":22},110,"The goal of this observational study is to investigate the accuracy of the device in characterizing perimenopausal and menopausal symptoms including vasomotor symptoms, anxiety, sleep quality compared to self-reported symptoms via an app. The main question it aims to answer is:\n\nWhat is the accuracy of the developed algorithm from the investigational device compared to daily self-report via an app in characterizing perimenopausal symptoms?\n\nParticipants will be asked to wear IndentifyHer's wearable non-invasive sensor and complete a daily electronic diary and questionnaires on stress, anxiety, and sleep.",[36,28,130,131,132,133,134,135],"Perimenopausal Insomnia","Perimenopausal Women","Menopausal Depression","Menopausal Hot Flashes","Menopausal and Postmenopausal Disorders","Menopausal Vasomotor Symptoms",[35,36,137,138,139,140,141],"Vasomotor symptoms","Hot flashes","IdentifyHer","Peri","Perimenopausal symptoms","RECRUITING","2025-09-17",{"date":145,"type":43},"2025-09-18",{"date":147,"type":43},"2025-07-04",{"date":149,"type":22},"2025-10",{"name":151,"class":152},"IdentifyHer Limited","INDUSTRY"]