[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"perinatal-mortality\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:perinatal-mortality":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100637574","perinatal-mortality-outcomes-through-household-infection-pathways-100637574",false,"NCT07620613","Perinatal Mortality Outcomes Through Household Infection Pathways","Effect of Cement Floors on Perinatal and Neonatal Mortality in Bangladesh: a Randomized Trial in Rural Bangladesh","POTH","Inclusion Criteria:\n\n* Prior enrollment in the CRADLE trial (NCT05372068), in either arm, and currently residing in the original CRADLE-enrolled household\n* Residence in Sirajganj or Tangail districts in Bangladesh\n* No major non-compliance (e.g., no removal of concrete floor in intervention arm or installation of concrete floor in control arm)\n* No plan to relocate within the study follow-up period\n* Incident pregnancy occurring after CRADLE trial enrollment, confirmed after 26 weeks gestation",true,"ALL","6 Years",{"count":21,"type":22},196,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this trial is to learn if replacing household soil floors with concrete floors can prevent deaths of infants around the time of birth, including stillbirths and deaths in the first month of life in rural Bangladesh. The primary question the study aims to answer is: Does residing in a home with a concrete vs. soil floor reduce the perinatal and neonatal morality in index children and their younger siblings up to 6 years post-installation of concrete floors?\n\nResearchers will compare participants in households with concrete floors (intervention) vs. soil floors (comparison group) to see if concrete floors reduce the rate of perinatal death and child death up the 6 years post-intervention.\n\nThis study will extend an ongoing NIH-funded randomized trial in which households with soil floors where a pregnant woman resided were randomly chosen to receive a concrete floor intervention or to retain their existing soil floor. This study will track pregnancies, births, and deaths among infants born to pregnant mothers in the original study to measure effects of household concrete flooring up to 6 years after the concrete floors were installed.",[28,29,30,31],"Stillbirth and Neonatal Mortality","Perinatal Mortality","Infant Mortality","Child Mortality",[33,34,35,36],"concrete floor","soil floor","dirt floor","housing intervention","NOT_YET_RECRUITING","2026-06-27",{"date":40,"type":41},"2026-07-01","ACTUAL",{"date":43,"type":22},"2026-06-01",{"date":45,"type":22},"2029-05-01",{"name":47,"class":48},"Stanford University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":17,"sex":18,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":66,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100636065","accelerating-maternal-and-newborn-survival-the-amani-study-100636065","NCT07560839","Accelerating Maternal and Newborn Survival: The AMANI Study","AMANI","Inclusion Criteria:\n\n* Member of the MPDSR committee\n* ≥18 years of age\n\nExclusion Criteria:\n\n* None","18 Years",{"count":59,"type":22},260,[25],"The goal of this cluster randomized controlled trial is to learn if a practice facilitation package (including both audit and feedback and enhanced mentorship) can increase the use of maternal and perinatal death surveillance and response (MPDSR) in Kenyan health facilities and reduce maternal and perinatal deaths. Twenty facilities will be enrolled (10 intervention; 10 control) and the intervention will be tested with facility staff including the MPDSR committee members and facility administrators. The main questions this study aims to answer are:\n\n* Does the practice facilitation package improve the reach, effectiveness, adoption, implementation, and maintenance of MPDSR in Kenyan health facilities?\n* What is the primary pathway through which the practice facilitation package influences MPDSR implementation with fidelity?\n\nResearchers will compare outcomes between the intervention and control facilities to see if the practice facilitation package influences the degree to which facility MPDSR committees can complete all of the steps of the MPDSR process.\n\nParticipants in both intervention and control facilities will be asked to respond to short surveys and engage in focus group discussions. Participants in the intervention facilities will be asked to engage regularly with the practice facilitators in enhanced mentorship and audit and feedback.",[63,64,65,29],"Maternal and Perinatal Death Surveillance and Response (MPDSR) Implementation","Maternal Mortality","Neonatal Mortality",[67,68,69,70],"practice facilitation","RE-AIM","audit and feedback","enhanced mentorship","2026-04-23",{"date":73,"type":41},"2026-05-01",{"date":75,"type":22},"2026-07",{"date":77,"type":22},"2029-06",{"name":79,"class":48},"University of Washington"]