[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"perineal-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:perineal-injury":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,79,103],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100623784","phase-4-improving-postoperative-recovery-a-study-of-multimodal-perineal-analgesia-protocol-mpap-after-vaginal-surgery-100623784",false,"NCT07401134","Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery","Improving Postoperative Recovery: A Randomized Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery","Inclusion Criteria:\n\n* Women ≥ 18 years of age\n* Undergoing perineorrhaphy and\u002For posterior colporrhaphy (rectocele repair\u002Fposterior repair) as part of their planned vaginal pelvic reconstructive surgery\n* Physically able to apply medicated witch-hazel pads (MAJOR® Medi-Pads) and administer topical benzocaine spray (Dermoplast®) to the perineal area\n* Able to understand and willing to provide informed consent\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to any of the study products or components, including witch hazel, benzocaine, aloe, or other product ingredients\n* Minors\n* Presence of an indwelling catheter expected to remain in place for ≥7 days postoperatively\n* History of chronic pelvic pain syndromes that may confound postoperative pain assessment, including interstitial cystitis\u002Fbladder pain syndrome (IC\u002FBPS), endometriosis, pudendal neuralgia, or vulvodynia\n* Chronic use (\\> 3 weeks of continuous use) of opioid pain medication\n* Presence of vulvar dermatoses such as lichen sclerosus, lichen planus, or lichen simplex chronicus\n* Currently pregnant or breastfeeding\n* Anticipated inability to complete postoperative follow-up, including physical or cognitive limitations that would impede self-care or completion of study diaries\n* Inability or unwillingness to provide informed consent or comply with study procedures","FEMALE","18 Years",{"count":19,"type":20},70,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","The purpose of this research is to determine if using perineal ice packs, medicated witch-hazel pads (MAJOR® Medi-Pads), and topical benzocaine spray (Dermoplast®) helps reduce perineal pain after perineorrhaphy and\u002For posterior colporrhaphy surgery.",[26,27,28],"Perineal Injury","Pain Vulva","Perineum; Injury","RECRUITING","2026-03-03",{"date":32,"type":33},"2026-03-04","ACTUAL",{"date":35,"type":33},"2026-02-18",{"date":37,"type":20},"2027-02",{"name":39,"class":40},"University of Miami","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":54,"conditions":55,"keywords":63,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":41},"100606012","physiotherapeutic-protocol-compared-to-usual-care-in-the-treatment-of-primiparas-after-perineal-trauma-100606012","NCT07170007","Physiotherapeutic Protocol Compared to Usual Care in the Treatment of Primiparas After Perineal Trauma","Physiotherapeutic Protocol Compared to Usual Care in the Treatment of Postpartum Primiparas After Perineal Trauma: A Type 1 Hybrid Effectiveness-Implementation Randomized Controlled Trial With Economic Evaluation","MPR","Inclusion Criteria:\n\n* The study will include female at birth aged 18 years or older, primiparous (no previous pregnancy after 16 weeks), who have suffered a perineal laceration of grade ≥2 or episiotomy, with ≥37 weeks of gestation at the time of delivery, who have not used testosterone in the last 6 months, with preserved cognitive ability, no history of neurological diseases, no symptoms of vaginal or urinary tract infection and no perineal diseases such as fistulas, genital mutilation, previous perineal surgery for pelvic floor dysfunction or Crohn's disease. According to the Robson 10-Group Classification System, only women belonging to group 1 (nulliparous women with a single vital cephalic pregnancy, ≥37 weeks of gestation in spontaneous labor) and group 2a (nulliparous women with a single vital cephalic pregnancy, ≥37 weeks of gestation who had labor induced) will be included in the study.\n\nExclusion Criteria:\n\n* Women with conditions such as severe pre-eclampsia or infections, sick newborns or women who refuse to take part in the study will not be included. Participation is voluntary and participants can withdraw from the study at any time.",{"count":51,"type":20},82,[53],"NA","The aim of this study is to assess the effectiveness of a pelvic floor muscle training (PFMT) protocol associated with cryotherapy initiated in the immediate postpartum period in relieving pain in primiparous women who suffered perineal trauma during vaginal delivery. This is a hybrid effectiveness-implementation type 1 randomized controlled trial with economic evaluation, which will include 82 primiparous women who suffered a perineal tear of grade 2 or above or episiotomy during vaginal delivery. The study participants will be selected from among the women who gave birth at the Hospital das Clínicas in Ribeirão Preto and will be randomly assigned to participate in one of two study groups: the Control Group will receive the usual maternity care, that includes suturing the injury and analgesic medication, and the Intervention Group will receive the usual care combined with a physiotherapy protocol of PFMT and cryotherapy, starting in the immediate postpartum period and lasting 3 months. The primary outcome of the study will be the change in perineal pain intensity assessed using an 11-point Numerical Rating Scale; and the secondary outcomes will be self-reported pelvic floor dysfunction, recovery from injury, functionality, health-related quality of life, use of pain medication, genital self-image and implementation outcomes (satisfaction, acceptability, adequacy, feasibility, equity and adherence to the protocol). Assessments will be carried out by a group of health professionals, including physiotherapists and physicians, at 11 points up to 6 months after delivery. Two doctors from the service will be responsible for carrying out the transperineal ultrasound examination to assess the injury, which will be sent to a third international collaborating physician (SD) to assess the results blindly. The other assessments will be carried out by two physiotherapists.Descriptive statistics will be used, including the ANOVA test to confirm homogeneity between the groups, the chi-square test or Fisher's test for categorical variables and Student's t-test or Wilcoxon's non-parametric test for independent samples for quantitative variables.",[56,57,58,26,59,60,61,62],"Episiotomy","Lacerations Perineal","Obstetric Anal Sphincter Injury","Perineal Laceration, Tear, or Rupture During Delivery","Perineal Pain","Perineal Tear Resulting From Childbirth","Perineal Tear and Episiotomy",[64,65,66,67,68,69],"pelvic floor dysfunction","woman's health","perineal pain","vaginal birth","perineal tear","postpartum","2025-11-24",{"date":72,"type":33},"2025-11-26",{"date":74,"type":33},"2025-11-11",{"date":76,"type":20},"2029-03-20",{"name":78,"class":40},"University of Sao Paulo",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":21,"phases":89,"briefSummary":91,"conditions":92,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":5},"100546336","phase-2-epsom-salt-compresses-to-relieve-perineal-for-postpartum-care-a-clinical-trial-100546336","NCT06393608","Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial","If the Use of Epsom Salt (magnesium Sulfate) Compresses 25% Effective in Relieving Perineal Pain in Immediate Postpartum Patients?","Inclusion Criteria:\n\n* Planned hospital stay at the mother-child unit of the Hôpital de Chicoutimi, Hôpital Charles-Le Moyne, or Hôpital Honoré-Mercier\n* Vaginal delivery with or without perineal tear, any degree of tear, including episiotomies\n* Obtaining consent for the study\n* Languages spoken: French, English or both\n\nExclusion Criteria:\n\n* Hemodynamic instability\n* Surgical procedure such as a cesarean section\n* Transfer to another hospital\n* Transfer to another care unit\n* Chronic use of narcotics\n* Inability to complete the logbook\n* Unsigned consent form",true,{"count":88,"type":20},90,[90],"PHASE2","The goal of this clinical trial is to determine if topical application of compresses soaked in 25% magnesium sulfate on painful perineum after birth is effective to alleviate pain.\n\nResearchers will compare this treatment to a placebo, compresses soaked in water. Participants will be invited to use their compresses if needed, for 15 minutes, up to four times a day, during their stay at the hospital after giving birth. They will also have to keep a diary of their usage and of their pain.",[26,93],"Pain","2024-12-16",{"date":96,"type":33},"2024-12-19",{"date":98,"type":33},"2024-06-15",{"date":100,"type":20},"2026-06-30",{"name":102,"class":40},"Antoine Roger",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":86,"sex":16,"minAge":17,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":21,"phases":113,"briefSummary":114,"conditions":115,"keywords":116,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":41},"100451932","the-use-of-st-johns-wort-oil-with-massage-in-the-perineum-during-childbirth-100451932","NCT05164926","The Use of St. John's Wort Oil With Massage in the Perineum During Childbirth","The Effects of the Use of St. John's Wort Oil With Massage in the Perineum on Episiotomy, Perineal Damage and Wound Healing","Inclusion Criteria:\n\n* normal pregnant women\n* active labor during the examination\n* pregnant woman who is likely to have a vaginal delivery\n\nExclusion Criteria:\n\n.Pregnant women with risky pregnancies","40 Years",{"count":112,"type":20},60,[53],"Perineal trauma, whether spontaneous or episiotomy, is a condition that affects the quality of life in primiparous women . In women who have experienced perineal trauma, problems such as dyspareunia, urinary and fecal incontinence, and delayed attachment of mother and baby occur in their later lives. Episiotomy, which is applied to reduce perineal trauma, is not recommended today, but it is still widely used.Different techniques such as perineal massage, hot compress, and Ritgen maneuver are applied to reduce perineal trauma. Perineal Massage can be applied together with oil. There are studies in which massage is applied together with oils.St. John's Wort (St. John's Wort) is a plant used in traditional practice in Turkish medicine against ulcers in the gastrointestinal tract, diabetes, jaundice, hepatic and biliary diseases. Antitumoral , antimicrobial , antiviral activities have been demonstrated. St. John's Wort oil can be used orally for dyspeptic complaints, and there is also a way to apply it through the skin. When applied for this purpose, it benefits from its facilitating feature of wound healing. It is useful in wound healing, myalgia and minor bruises, burn pain .\n\nThe investigators'aim in this study is to investigate the effects of perineal massage with St. John's Wort oil on episiotomy, perineal damage and wound healing.",[26],[117,118,119,120,121],"perineal injury","perineal massage","St. John's Wort oil","Visual analogue scoring","episiotomy","2024-07-30",{"date":124,"type":33},"2024-07-31",{"date":126,"type":33},"2023-05-15",{"date":128,"type":20},"2024-12-30",{"name":130,"class":40},"Ankara City Hospital Bilkent"]