[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"perioperative-anemia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:perioperative-anemia":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100494117","phase-4-the-effects-of-ferric-derisomaltose-on-postoperative-anemia-in-spinal-deformity-surgery-100494117",false,"NCT05714007","The Effects of Ferric Derisomaltose on Postoperative Anemia in Spinal Deformity Surgery","The Effects of Ferric Derisomaltose on Postoperative Anemia in Patients Undergoing Spinal Deformity Surgery: A Prospective Randomized Controlled Study","Inclusion Criteria\n\n1. Age ≥18 years\n2. Received spinal deformity surgery\n3. 70 g\u002FL ≤ Hb ≤ 110 g\u002FL at POD1, or Hb at POD1 showed a decrease of\n\n   ≥20 g\u002FL compared with baseline\n4. Informed consent was obtained voluntarily\n\nExclusion Criteria\n\n1. Women who are pregnant, breastfeeding, or planning to become pregnant.\n2. known serious hypersensitivity to other parenteral iron products\n3. Non-iron deficiency anemia (e.g., hemolytic anemia)\n4. Decompensated liver insufficiency\n5. Coexisting active infection\n6. Drug abuse, including but not limited to opioids, amphetamines, methamphetamine, ketamine, etc.\n7. Other conditions that the investigator considers inappropriate for participation (e.g. deafness, Parkinson's disease, communication disorders, etc.)\n8. Participation in another clinical trial within three months prior to this study.","ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","The prognosis of patients undergoing spinal deformity surgery is often compromised by perioperative anemia due to iron deficiency. The aim of this randomized, controlled trial was to evaluate whether postoperative ferric derisomaltose intravenous injection may improve anemia and prognosis in patients undergoing spinal deformity surgery comparing with oral iron. Participants will be randomly assigned to the treatment group (intravenous ferric derisomaltose) and the control group (oral iron). Changes in hemoglobin concentration, percentage of anemia correction, changes in iron indicators, patient quality of life, and incidence of adverse events will be analyzed to evaluate the efficacy and safety of iron isomaltoside infusion.",[26,27,28,29],"Perioperative Anemia","Surgery","Spinal Deformity","Adult",[31,32,33,34],"spinal deformity surgery","perioperative anemia","ferric derisomaltose","adult","RECRUITING","2025-06-10",{"date":38,"type":39},"2025-06-13","ACTUAL",{"date":41,"type":39},"2023-08-31",{"date":43,"type":20},"2025-12",{"name":45,"class":46},"Peking Union Medical College Hospital","OTHER"]