[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"perioperative-outcomes\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:perioperative-outcomes":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100427929","protocol-based-management-and-perioperative-outcomes-in-patients-with-chronic-antithrombotic-therapy-100427929",false,"NCT04852406","Protocol-based Management and Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy","Effect of Protocol-based Management on Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy: a Pragmatic Interventional Study","Inclusion Criteria:\n\n* 1\\. Patients with continuing antithrombotic therapy (including antiplatelet and\u002For anticoagulant therapies) for cardiovascular and cerebrovascular diseases for more than 2 weeks.\n* 2\\. Patients who have one or more of the following situations: (1) non-valvular atrial fibrillation with a CHA2DS2-VASc score \\>4; (2) post-artificial valve replacement (including mitral valve, ball-cage valve or tilting disc aortic valve); (3) venous thromboembolism occurred within 1 year, or venous thromboembolism with other high-risk factors which require long-term anticoagulation treatment; (4) coronary heart disease with coronary stent implantation, thrombolytic therapy or other coronary procedures within 2 years, or who had undergone coronary artery bypass grafting within 1 year, or who experienced myocardial infarction or acute coronary syndrome within 1 year; (5) a history of stroke\u002Ftransient ischemic accident within 1 year, or a history of cervical or intracranial revascularization treatment within 1 year; (6) peripheral arterial disease.\n* 3\\. Patients who are scheduled to undergo intra-abdominal surgery (including general and urologic surgery).\n* 4\\. Patients who sign written informed consents.\n\nExclusion Criteria:\n\n* 1\\. Refuse to participate.\n* 2\\. Emergency surgery.\n* 3\\. Unable to complete the preoperative assessment and follow-up plan.\n* 4\\. Other reasons that are considered unsuitable for study participation by the investigators or the attending doctors.","ALL",{"count":18,"type":19},526,"ESTIMATED","INTERVENTIONAL",[22],"NA","The purpose of this pragmatic interventional study is to evaluate whether a protocol-based management of antithrombotic drugs can reduce a composite of perioperative outcomes in patients with chronic antithrombotic therapy before surgery.",[25,26,27],"Antithrombotic Therapy","Perioperative Care","Perioperative Outcomes",[29,30,31],"perioperative care","antithrombotic therapy","perioperative outcomes","RECRUITING","2025-07-30",{"date":35,"type":36},"2025-07-31","ACTUAL",{"date":38,"type":36},"2021-04-21",{"date":40,"type":19},"2026-01",{"name":42,"class":43},"Peking University First Hospital","OTHER"]