[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"perioperative-pain-management\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:perioperative-pain-management":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100587189","phase-4-comfort-trial-complex-obstetric-management-with-focused-regional-transversus-abdominis-plane-block-100587189",false,"NCT06925152","COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block","COMFORT","Inclusion criteria:\n\nPatient has a history of a least one of the following:\n\n* Prior exploratory laparotomy\n* History of non-obstetric open intra-abdominal surgery\n* History of three or more prior cesarean deliveries\n* History of intra-abdominal or pelvic adhesive disease\n* History of abdominoplasty\n* History of abdominal re-exploration surgery\n\nExclusion Criteria:\n\n* Received general anesthesia\n* History of less than 3 cesarean deliveries if do not meet other inclusion criteria\n* History of chronic opioid use\n* History of substance abuse (i.e. alcohol, methamphetamine\u002Famphetamine, abuse of prescription opioid medication, or heroin use)\n* History of chronic kidney disease\n* Allergies to bupivacaine or oral analgesics\n* Patient preference\n* Cesarean hysterectomy\n* Administration of ≥4mg morphine to epidural\n* Loss to follow-up","FEMALE","18 Years","50 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean delivery (CD) in the setting of complex obstetric surgery (COS).",[27,28,29,30],"Complex Obstetric Surgery","Perioperative Pain Management","Cesarean Delivery","Postoperative Pain Control",[32,33,34,35],"Complex obstetric surgery","Perioperative pain management","cesarean delivery","postoperative pain control","RECRUITING","2026-03-08",{"date":39,"type":40},"2026-03-11","ACTUAL",{"date":42,"type":40},"2025-07-15",{"date":44,"type":21},"2028-05",{"name":46,"class":47},"University of Tennessee","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":64,"conditions":65,"keywords":66,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":48},"100552027","the-efficacy-of-music-on-perioperative-pain-management-100552027","NCT06467747","The Efficacy of Music on Perioperative Pain Management","The Efficacy of Intraoperative Music Stimulation on Perioperative Pain Management","Inclusion Criteria:\n\n* Older than 20 years old and younger than 80 years old\n* male or female\n* Scheduled for minimally invasive surgery (laparoscopic cholecystectomy, appendectomy)\n* Ambulatory surgery\n* American Society of Anesthesiologists (ASA) physical status I\\~III\n\nExclusion Criteria:\n\n* Severe hearing impairment\n* Severe pulmonary or cardiovascular disease\n* Brain or central nervous system (CNS) disorder\n* Long-term systemic steroid or daily morphine treatment\n* Pregnant women\n* Emergency surgery\n* The absence of informed consent",true,"ALL","20 Years","80 Years",{"count":61,"type":21},90,[63],"NA","The goal of this clinical trial is to learn if intraoperative music stimulation works to alleviate perioperative pain in surgical patients undergoing general anesthesia. It will also learn about the possible mechanisms by how music affects pain.\n\nThe main questions it aims to answer are:\n\nDoes music lower the number of times participants need to use a rescue analgesic? What changes occur in electroencephalogram (EEG) and nociception monitors when participants listen to music? Researchers will compare music to mute or control (hear ambient sounds without earphones) to see if music works to alleviate perioperative pain.\n\nParticipants will listen music or mute or ambient sounds throughout the operation, and receive routine anesthesia care.",[28],[67],"Music therapy","2024-08-07",{"date":70,"type":40},"2024-08-09",{"date":72,"type":40},"2024-07-03",{"date":74,"type":21},"2025-05",{"name":76,"class":47},"Taichung Tzu Chi Hospital"]