[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"perioperative-respiratory-mechanics\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:perioperative-respiratory-mechanics":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100615634","effect-of-sevoflurane-vs-desflurane-on-mechanical-power-in-laparoscopic-cholecystectomy-100615634",false,"NCT07295158","Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy","Laparoscopic Cholecystectomy Patients: Effect of Sevoflurane vs. Desflurane on Mechanical Power - A Prospective, Randomized, Controlled Trial","VAPOR","Inclusion Criteria:\n\n* Adults aged 18-65 years\n\nASA Physical Status I-II\n\nScheduled for elective laparoscopic cholecystectomy\n\nAble to provide written informed consent\n\nExclusion Criteria:\n\nKnown hypersensitivity or contraindication to study medications (sevoflurane or desflurane)\n\nSevere chronic obstructive pulmonary disease (COPD)\n\nUncontrolled bronchial asthma\n\nDecompensated heart failure (NYHA Class III-IV)\n\nHistory of prior lung surgery\n\nMorbid obesity (BMI \\> 35 kg\u002Fm²)\n\nPregnancy\n\nRefusal to participate or inability to provide informed consent\n\n\\-","ALL","18 Years","65 Years",{"count":21,"type":22},138,"ESTIMATED","INTERVENTIONAL",[25],"NA","This single-center, prospective, randomized, assessor-blinded clinical trial aims to compare the effects of sevoflurane and desflurane anesthesia on intraoperative mechanical power in adult patients undergoing elective laparoscopic cholecystectomy. Mechanical power will be measured at three standardized time points using a validated formula, and secondary outcomes include driving pressure values and early postoperative respiratory complications (desaturation, laryngospasm, bronchospasm, cough).",[28],"Perioperative Respiratory Mechanics","RECRUITING","2026-03-12",{"date":32,"type":33},"2026-03-13","ACTUAL",{"date":35,"type":33},"2026-03-09",{"date":37,"type":22},"2026-05-30",{"name":39,"class":40},"Konya City Hospital","OTHER"]