[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"peripheral-lung-lesions\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:peripheral-lung-lesions":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,41,72,107],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100580979","diagnosing-peripheral-lung-lesions-with-cryo-biopsies-100580979",false,"NCT06844344","Diagnosing peRipheral Lung Lesions With CRYO Biopsies","DR CRYO","Inclusion Criteria:\n\n* \\- Patients undergoing diagnostic work-up for lung cancer due to a lung lesion surrounded by normal lung tissue (identified by CT)\n* Age 18 or above\n* Bronchoscopy with planned forceps sampling from the lesion\n\nExclusion Criteria:\n\n* \\- Pregnancy\n* Not able to provide informed consent.","ALL","18 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","Lung cancer is the leading course of cancer related deaths world-wide. Lung cancer screening will increase the number of small lung lesion in need of biopsy to confirm the diagnosis. Obtaining lung biopsies with a bronchoscopy has the lowest risk of complications (1-2%) compared to other modalities such as transthoracic needle biopsy (20%), however diagnostic yield needs improvement. Currently a diagnosis is established in 50- 70% of the bronchoscopic procedures depending on the step-up. One way to improve the yield would be by using a cryo probe through the bronchoscope which freezes a small part of the lung for extraction, and thereby provides larger biopsies for examination. This will increase the chances of obtaining sufficient material from a small lesion to determine the diagnosis.\n\nThe DR CRYO study will compare cryo biopsies to forceps biopsies for the diagnosis of peripheral lung lesions.\n\nWe hope that the cryo biopsies can improve the diagnostic capabilities of bronchoscopy and provide better biopsies for tumor marker analyses. The project is relevant both for patients undergoing diagnostic work-up for lung cancer in early stages .",[26,27],"Lung Cancer","Peripheral Lung Lesions","RECRUITING","2026-05-16",{"date":31,"type":32},"2026-05-20","ACTUAL",{"date":34,"type":32},"2025-03-01",{"date":36,"type":20},"2027-02-01",{"name":38,"class":39},"Odense University Hospital","OTHER",2,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":48,"targetDuration":50,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":57,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100639257","3d-us-construct-on-volumetric-assessment-of-lung-disease--clinical-application-100639257","NCT07574255","3D-US Construct on Volumetric Assessment of Lung Disease & Clinical Application","Three-dimensional Ultrasonic Construct on Volumetric Assessment of Lung Disease and Its Clinical Application","Inclusion Criteria:\n\n* Participants suspect with lung lesions referred for ultrasound workup\n\nExclusion Criteria:\n\n* Participants aged \\\u003C 18 years\n* Participants refusal\n* Participants with implanted metal in scanning area interfering data collection\n* Participants who cannot perform breath holding for at least 1 second",{"count":49,"type":20},300,"6 Months","OBSERVATIONAL","The goal of this observational study is to establish the three-dimensional construct of lung lesion via ultrasound in patients with peripheral lung lesions or any superficial lesion in thoracic fields. The primary question our study aims to answer is:\n\nWhether the 3D ultrasound morphology can reflect lung disease entities? Whether the 3D volumetric follow-up protocol can be standardised to reflect lung disease status?",[54,55,27,56],"Lung Ultrasound","Lung Cancer (Diagnosis)","Ultrasound Assessment",[58,59,60],"lung ultrasound","three-dimensional ultrasound","peripheral lung lesions","NOT_YET_RECRUITING","2026-05-03",{"date":64,"type":32},"2026-05-07",{"date":66,"type":20},"2026-05-30",{"date":68,"type":20},"2031-02-28",{"name":70,"class":39},"National Taiwan University Hospital",1,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":81,"targetDuration":50,"studyType":51,"phases":4,"briefSummary":82,"conditions":83,"keywords":88,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":71},"100597373","shape-sensing-robotic-assisted-bronchoscopy-for-diagnosis-of-peripheral-pulmonary-nodules-in-korea-100597373","NCT07057648","Shape-Sensing Robotic-Assisted Bronchoscopy for Diagnosis of Peripheral Pulmonary Nodules in Korea","Shape-sensing Robotic-assisted Bronchoscopy (ssRAB) for Diagnosis of Peripheral Pulmonary Nodules: A Prospective Cohort Study in Korea (the ULSAN-ION Study)","ULSAN-ION","Inclusion Criteria:\n\n* Adults aged 19 years or older\n* Solid or part-solid peripheral pulmonary nodules confirmed on chest computed tomography (CT)\n* Patients requiring histological diagnosis as determined by the treating physician\n* Patients eligible for bronchoscopy procedure\n* Ability to provide written informed consent\n* Eastern Cooperative Oncology Group (ECOG) performance status 0-2 or equivalent functional status allowing procedure under sedation or general anesthesia\n\nExclusion Criteria:\n\n* Pure ground glass opacity nodules\n* Bleeding tendency defined as platelet count less than 50,000\u002FμL or International Normalized Ratio (INR) greater than 1.5\n* Severe cardiopulmonary dysfunction precluding deep sedation or general anesthesia\n* Pregnant or breastfeeding women\n* Life expectancy less than 6 months as assessed by the treating physician\n* Inability or unwillingness to provide informed consent\n* Absolute contraindication to bronchoscopy including:\n\n  * Severe hypoxemia (oxygen saturation \\\u003C90% on room air)\n  * Severe pulmonary hypertension\n  * Recent myocardial infarction (within 6 weeks)\n  * Unstable angina\n  * Malignant arrhythmias\n* Participation in another interventional clinical trial that may interfere with study procedures or outcomes","19 Years",{"count":19,"type":20},"What is this study about? This study tests a new robotic technology to take tissue samples from lung nodules (small spots in the lungs). Some lung nodules are cancer, but doctors need a tissue sample to know for sure.\n\nWhat is the problem? Current methods to get tissue from lung nodules only work about 7 out of 10 times. When they don't work, doctors may need riskier procedures.\n\nWhat is the new technology? The new technology is called robotic bronchoscopy (ssRAB). It uses a robot with special sensors to guide a thin tube more accurately to lung nodules than current methods.\n\nWho can join? Adults aged 19 or older who have lung nodules that need tissue sampling and are healthy enough for the procedure.\n\nWhat happens? Participants will have the robotic procedure while asleep under anesthesia. The robot guides a thin tube to the lung nodule to take a small tissue sample. Participants are watched for problems and followed for 6 months.\n\nWhat are the risks and benefits? The new technology may be more accurate and safer than current methods. The main risks are small chance of lung collapse or bleeding, similar to regular procedures.\n\nWhy is this important? This study will show if the new robotic technology works well and is safe in Korea. If successful, it could help diagnose lung cancer earlier and more accurately.\n\nThis study will include 100 people at Ulsan University Hospital in Korea.",[84,27,85,86,87],"Lung Nodules","Pulmonary Nodules","Lung Cancers","Bronchoscopy",[89,90,91,92,93,84,94,95,96,97],"Shape-sensing robotic-assisted bronchoscopy","ssRAB","Robotic bronchoscopy","Peripheral lung nodules","Diagnostic yield","Navigation bronchoscopy","Lung biopsy","Korea","Prospective cohort","2026-02-10",{"date":100,"type":32},"2026-02-13",{"date":102,"type":32},"2025-07-09",{"date":104,"type":20},"2027-05-31",{"name":106,"class":39},"Ulsan University Hospital",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":113,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":115,"enrollmentInfo":116,"targetDuration":4,"studyType":21,"phases":118,"briefSummary":119,"conditions":120,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":40},"100547770","comparison-of-the-diagnostic-accuracy-us-guided-percutaneous-lung-biopsies-vs-ct-guided-in-peripheral-lung-lesions-100547770","NCT06412289","Comparison of the Diagnostic Accuracy: US-guided Percutaneous Lung Biopsies vs CT-guided in Peripheral Lung Lesions","A Prospective, Randomized, Multicentric and Single-blinded Study on Accuracy and Safety of Ultrasound (US) Guided Percutaneous Needle Biopsy of Peripheral Lung Lesion Compared With Computed TomogrAphy (CT) Guided Needle Biopsy","SULTAN","Inclusion Criteria:\n\n* Willingness and ability to provide free and informed consent. Age older then 18 years old.\n* Peripheric pulmonary lesions adherent to the thoracic wall in CT scans with indication to typing\n\nExclusion Criteria:\n\n* Inability to provide free and informed consent, in the absence of an available legal guardian.\n* Age younger then 18 years old.\n* Terminal neoplastic diseases\u002F palliative care patients.\n* Patients with one lung, anatomical of functional.\n* Severe non-treatable blood clothing disfunctions.\n* Severe organ failure (pulmonary, renal, hepatic or cardiac).\n* Women in state of pregnancy.","90 Years",{"count":117,"type":20},236,[23],"A non-sponsored prospective randomized single-blind national multicenter interventional study which aims to compare the diagnostic accuracy between US-guided percutaneous lung needle biopsies and CT-guided in peripheral lung lesions. Secondary endpoints are:\n\n* onset of number and type of complications during and after the procedure, within the first three hour;\n* exposition to ionizing radiation, in milligray(mGy);\n* patient comfort during the procedure;\n* duration of the procedure,",[27],"2024-12-03",{"date":123,"type":32},"2024-12-06",{"date":125,"type":32},"2024-03-08",{"date":127,"type":20},"2026-10-31",{"name":129,"class":39},"University Hospital of Ferrara"]