[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"periventricular-white-matter-abnormalities\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:periventricular-white-matter-abnormalities":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100560295","predicting-cerebral-palsy-in-infants-with-white-matter-injury-using-mri-100560295",false,"NCT06575283","Predicting Cerebral Palsy in Infants With White Matter Injury Using MRI","Early Prediction of Cerebral Palsy by MRI in Infants With White Matter Injury: a Multicenter Study","Inclusion Criteria:\n\n1. Infants and children at high risk of periventricular white matter injury (PVWMI) (gestational age \\\u003C35 weeks, birth weight \\\u003C2.6 kg, forceps-assisted delivery\u002Ffetal head attraction, Apgar score \\\u003C7, hypoglycaemia, sepsis, electrolyte disturbances, premature rupture of membranes);\n2. Those who underwent MRI at 6 months of age-2 years, including at least T1WI and T2WI sequences;\n3. Upon follow-up, the patient's clinical diagnosis: cerebral palsy, other diagnoses that did not develop into cerebral palsy, or inability to confirm the diagnosis).\n\nExclusion Criteria:\n\n1. Incomplete MRI images or unreadable images due to motion artefacts;\n2. Incomplete neurobehavioural assessment data (including: gross motor function).",true,"ALL","6 Months","2 Years",{"count":21,"type":22},1000,"ESTIMATED","OBSERVATIONAL","The goal of this study is to determin the MRI features associated with cerebral palsy and to develop prediction models of pediatric disorders by combining MRI with artificial intelligence.\n\nThe main questions it aims to answer are:\n\n* How to achieve features on conventional MRI associated with cerebral palsy?\n* How to predict the risk of cerebral palsy in infants aged 6 to 2 years based on conventional MRI and deep learning? Researchers will compare characteristics of periventricular white matter injury with cerebral palsy to those without cerebral palsy.\n\nParticipants will be asked to provide MRI data, clinical diagnoses information, and follow-up outcomes.",[26,27],"Cerebral Palsy","Periventricular White Matter Abnormalities",[29,30,31,32],"Cerebral palsy","Periventricular white matter injury","MRI","Deep learning","NOT_YET_RECRUITING","2024-09-04",{"date":36,"type":37},"2024-09-19","ACTUAL",{"date":39,"type":22},"2024-09-01",{"date":41,"type":22},"2025-12-31",{"name":43,"class":44},"First Affiliated Hospital Xi'an Jiaotong University","OTHER"]