[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"phantom-limb-pain-plp\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:phantom-limb-pain-plp":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":4},"100626681","post-amputation-stump-infection-as-a-predictor-of-persistent-residual-limb-pain-a-prospective-cohort-study-100626681",false,"NCT07438795","Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study","INF-STUMP-PAIN","Inclusion Criteria:\n\n* Traumatic upper or lower limb amputation\n* Enrollment within 4 weeks after surgery\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Pre-existing chronic pain in the affected limb\n* Severe cognitive impairment\n* Terminal illness limiting follow-up\n* Refusal or inability to complete follow-up assessments","ALL","18 Years","60 Years",{"count":20,"type":21},150,"ESTIMATED","6 Months","OBSERVATIONAL","Persistent residual limb pain is common after traumatic amputation and significantly impairs rehabilitation and prosthetic use. Postoperative stump infection may contribute to peripheral nerve sensitization, scar fibrosis, and long-term pain persistence. This prospective cohort study aims to determine whether early post-amputation stump infection independently predicts persistent clinically significant residual limb pain at 3 and 6 months after surgery.",[26,27,28,29,30],"Residual Limb Pain","Stump Pain","Post-Amputation Pain","Surgical Site Infection","Phantom Limb Pain (PLP)",[32,33,34,35,36,37,38],"Traumatic amputation","stump infection","residual limb pain","chronic pain","surgical site infection","blast injury","neuropathic pain","NOT_YET_RECRUITING","2026-06-01",{"date":42,"type":43},"2026-06-03","ACTUAL",{"date":45,"type":21},"2026-06-23",{"date":47,"type":21},"2026-12-23",{"name":49,"class":50},"Ukrainian Society of Regional Anesthesia and Pain Therapy","OTHER",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":65,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":79},"100522025","immersive-healing-the-therapeutic-potential-of-virtual-reality-100522025","NCT06077227","Immersive Healing: The Therapeutic Potential of Virtual Reality","Immersive Healing: The Therapeutic Potential of Virtual Reality in Phantom Limb Experience","Inclusion Criteria:\n\n* History of major limb amputation\n* Age \\> 18 years old\n* Presence of phantom limb pain or negative phantom sensation(s)\n\nExclusion Criteria:\n\n* Active mental illness, neurological disease, or cognitive impairment that would interfere with survey completion\n* Those without phantom limb pain or negative phantom limb sensations\n* Non-English speaking",{"count":59,"type":21},20,"INTERVENTIONAL",[62],"NA","Phantom limb pain (PLP) is a significant and pervasive issue among upper limb amputees, severely impacting their quality of life. The literature delineating prevalence of upper versus lower limb amputations is limited, but the prevalence of total amputations in the United States is estimated to reach 3 million individuals by 2050, with approximately 185,000 new cases annually. PLP affects 60-68% of these patients, leading to heightened levels of anxiety, depression, and reduced overall well-being.",[30],[66,67,68],"amputee","pain management","virtual reality (VR) therapy","RECRUITING","2025-10-29",{"date":72,"type":43},"2025-10-31",{"date":74,"type":43},"2023-12-21",{"date":76,"type":21},"2026-10",{"name":78,"class":50},"Wake Forest University Health Sciences",1]