[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"phantom-pain-following-amputation-of-lower-limb\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:phantom-pain-following-amputation-of-lower-limb":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100596351","efficacy-and-mechanisms-of-virtual-reality-treatment-of-phantom-leg-painhome-based-treatment-100596351",false,"NCT07044323","Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment","PLP Home-Based","Inclusion Criteria:\n\n* Age 18 -100\n* Capacity to provide Informed Consent\n* Unilateral above or below knee amputation more than 3 months prior to enrollment\n* Absence of cognitive impairment, operationally defined as a Montreal Cognitive Assessment score of 18 or greater1.\n* Pain averaged over the preceding 1 month in the phantom limb rated as greater than 4 on a scale of 0-10.\n\nExclusion Criteria:\n\n* History of significant medical or neurological disorder such as stroke or moderate to severe traumatic brain injury (operationally defined as loss of consciousness for more than 30 minutes)\n* History of significant or poorly controlled psychiatric disorders\n* Substantial depression or anxiety affecting their ability to perform tasks necessary for the study.\n* Current abuse of alcohol or drugs, prescription or otherwise\n* Nursing a child, pregnant, or intent to become pregnant during the study","ALL","18 Years","100 Years",{"count":20,"type":21},44,"ESTIMATED","INTERVENTIONAL",[24],"NA","After amputation of an arm or leg, up to 90% of subjects experience a \"phantom limb\", a phenomenon characterized by persistent feelings of the missing limb. Many subjects with a phantom limb experience intense pain in the missing extremity that is often poorly responsive to medications or other interventions. The study will explore the feasibility and efficacy of a home-based, active VR treatment for phantom limb pain (PLP).",[27,28],"Phantom Pain Following Amputation of Lower Limb","Amputation",[30,31,32,33],"pain","phantom limb","lower limb amputation","treatment","RECRUITING","2025-08-07",{"date":37,"type":38},"2025-08-08","ACTUAL",{"date":40,"type":38},"2025-06-16",{"date":42,"type":21},"2026-05-31",{"name":44,"class":45},"Albert Einstein Healthcare Network","OTHER",3]