[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"phantom-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:phantom-pain":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,58],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":34,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":5},"100523328","prospective-study-of-sensation-and-satisfaction-in-cancer-and-transgender-mastectomy-patients-100523328",false,"NCT06094257","Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients","Prospective Cohort Study Comparing Sensory Outcome, Development of Chronic Pain and Phantom Pain, as Well as Patient Satisfaction in Cancer and Transgender Patients Undergoing Mastectomy and Reconstruction With and Without Reinnervation.","Inclusion Criteria:\n\n* Age over 18\n* Patient is scheduled for gender mastectomy surgery (including nipple sparing mastectomy and mastectomy with free nipple graft) or NSM with breast implant or autologous reconstruction\n* Patient is capable and willing to provide informed consent\n\nExclusion Criteria:\n\n* Patient has a nerve condition that does not allow for assessment of sensation\n* Any subject who at the discretion of the Investigator is not suitable for inclusion in the study or is unlikely to comply with follow-up schedule\n* Currently prescribed medication known to impact nerve regeneration or to cause peripheral neuropathy\n* Bilateral reconstruction with non-uniform treatment (i.e. 1 reconstructed breast is non-neurotized, 1 reconstructed breast is neurotized)",true,"ALL","18 Years",{"count":20,"type":21},400,"ESTIMATED","OBSERVATIONAL","During breast surgery, sensory nerves are cut which may lead to reduced sensation and pain. Surgical reinnervation techniques have been developed with the aim of improving postoperative sensation by preserving the nerves and connecting them to the nipple and areola. The investigators aim to compare postoperative sensation and patient reported outcomes in patients undergoing reinnervation versus those not undergoing reinnervation to determine if there is a difference. The investigators will investigate this in patients undergoing gender-affirming mastectomy, implant-based breast reconstruction and autologous breast reconstruction. The investigators will use various tools that measure sensation quantitatively.",[25,26,27,28,29,30,31,32,33],"Sensation Disorders","Sensation, Phantom","Pain, Postoperative","Pain, Chronic","Numbness","Sensory Disorder","Sensory Defect","Phantom Pain","Phantom Sensation",[35,36,37,38,39,40,41,42,43,44,45],"Sensation","Reinnervation","Peripheral nerve","Reconstruction","Breast reinnervation","Chest reinnervation","Gender-affirming mastectomy","Breast reconstruction","Peripheral nerve repair","Targeted nipple areolar complex","Targeted nipple areolar complex reinnervation","RECRUITING","2025-08-26",{"date":49,"type":50},"2025-08-27","ACTUAL",{"date":52,"type":50},"2022-02-09",{"date":54,"type":21},"2033-03",{"name":56,"class":57},"Weill Medical College of Cornell University","OTHER",{"id":59,"slug":60,"hasResults":11,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":66,"enrollmentInfo":67,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":69,"conditions":70,"keywords":71,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":4},"100481158","neural-bases-of-phantom-pain-after-amputation-100481158","NCT05545358","Neural Bases of Phantom Pain After Amputation","Experimental Study of the Neural Bases of Phantom Pain After Amputation and Their Modification by Proprioceptive Training: MRI Study of the Brain and Spinal Cord","Phantom limb","Inclusion Criteria:\n\n* Between 18 and 65 years old\n* For the \"amputees with phantom pain\" group: patients who have been amputated for more than 2 years and have chronic phantom pain\n* For the \"amputees without phantom pain\" group: patients who have been amputated for more than 2 years and do not have chronic phantom pain\n* For the \"healthy participants\" group: healthy participants with no neurological history\n\nExclusion Criteria:\n\n* Clinically significant pathology (gastrointestinal, renal, hepatic, endocrine, cardiovascular or respiratory)\n* Progressive psychiatric or neurological pathology\n* On psychotropic medication\n* Pregnant or nursing woman\n* Inadequate level of French language","65 Years",{"count":68,"type":21},75,"The amputation of a limb results in chronic pain associated with the lost limb in the majority of patients, which persists over time. Despite a large number of studies conducted in an attempt to elucidate the neural basis of phantom pain, these are still not elucidated and current treatments often fail to relieve patients' pain.",[32],[72,73],"fMRI","spinal fMRI","NOT_YET_RECRUITING","2022-09-16",{"date":77,"type":50},"2022-09-19",{"date":79,"type":21},"2022-10",{"date":81,"type":21},"2026-10",{"name":83,"class":57},"Direction Centrale du Service de Santé des Armées"]