[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"physical-deconditioning\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:physical-deconditioning":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,68],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100609137","development-of-a-power-training-program-to-improve-mobility-in-older-veterans-100609137",false,"NCT07210645","Development of a Power Training Program to Improve Mobility in Older Veterans","Inclusion Criteria:\n\nPilot Study Criteria:\n\n* Veterans 65 years of age and older\n* New enrollees of the Rocky Mountain Regional Gerofit Program\n* ability to function independently in a group setting\n\nExclusion Criteria:\n\n* inability to perform basic activities of daily living\n* oxygen dependency\n* unstable cardiac disease\n* moderate to severe cognitive impairment (Montreal cognitive assessment scores \\\u003C 24)\n* proliferative diabetic retinopathy\n* relative exclusions for participation in the in-person Gerofit exercise program including: open wounds, incontinence, and lack of transportation\n* inability to ambulate\n* progressive neurological diagnoses (e.g. Amyotrophic lateral sclerosis, Parkinson's disease, multiple sclerosis)\n* individuals with planned orthopedic surgeries in the next 3 months","ALL","65 Years",{"count":18,"type":19},30,"ESTIMATED","INTERVENTIONAL",[22],"NA","The overall purpose of this study is to develop a power training intervention in partnership with Veterans participating in Gerofit and to evaluate the program's acceptability, feasibility, and preliminary participant outcomes (leg power, physical function and self-report participation).",[25,26],"Physical Deconditioning","Mobility Decline",[28,29,30,31],"power training","mobility","older adult","user-centered design","NOT_YET_RECRUITING","2026-06-18",{"date":35,"type":36},"2026-06-23","ACTUAL",{"date":38,"type":19},"2026-07-13",{"date":40,"type":19},"2030-12-31",{"name":42,"class":43},"VA Office of Research and Development","FED",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":15,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":20,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":4},"100630980","effects-of-training-with-a-pressure-cuff-on-cellular-energy-activity-100630980","NCT07494721","Effects of Training With a Pressure Cuff on Cellular Energy Activity","Influence of Short-Term Conventional Cuff-Assisted Training on Mitochondrial Capacity: A Non-Invasive Investigation","Inclusion:\n\n* Medically confirmed generalized deconditioning with reduced muscle strength\n* Medical certification of suitability for functional lower-extremity strength training\n* Written informed consent after an adequate reflection period\n\nExclusion:\n\n* Unstable arrhythmias, myocardial ischemia, symptomatic blood pressure drops or hypertension (\\>160\u002F100 mmHg despite medication)\n* History of thrombosis or acute swelling\u002Fskin discoloration of the legs\n* Dizziness, confusion, cyanosis, or unexplained fatigue\n* Participant's wish to withdraw or not participate","18 Years",{"count":54,"type":19},51,[22],"This study investigates low-load, cuff-assisted training to improve mitochondrial capacity. The intervention is carried out using automated pressure cuffs, applying an individualized pressure of 70% of the limb occlusion pressure. This approach reflects the current scientific consensus for safe and effective use in clinical populations.\n\nWithin a rehabilitation setting, two training modalities are compared: intermittent strength training and alternating continuous endurance training. Muscle oxygen saturation is measured non-invasively using near-infrared spectroscopy.",[25],"2026-03-26",{"date":60,"type":36},"2026-04-01",{"date":62,"type":19},"2026-07",{"date":64,"type":19},"2026-12",{"name":66,"class":67},"Spital Thurgau AG","OTHER",{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":15,"minAge":75,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":20,"phases":78,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":44},"100538254","multicomponent-telerehabilitation-to-engage-veterans-in-effective-self-management-of-complex-health-conditions-100538254","NCT06288438","Multicomponent Telerehabilitation to Engage Veterans in Effective Self-Management of Complex Health Conditions","Multicomponent Telerehabilitation to Engage Veterans in Effective Self-Management of ComplexHealth Conditions","Inclusion Criteria:\n\n* 60 years of age and older\n* Multiple chronic conditions (Functional Comorbidity Index \\> or = 3)\n* Impaired physical function (\\\u003C or = 8 repetitions on 30 second sit to stand test)\n\nExclusion Criteria:\n\n* Life expectancy \\\u003C 12 months\n* Acute or progressive neurological disorder (e.g. amyotrophic lateral sclerosis, recent stroke)\n* Moderate to severe dementia (\\\u003C11 on telephone Montreal Cognitive Assessment(T-MoCA))\n* Medical conditions precluding safe participation in high-intensity rehabilitation (e.g. unstable angina)","60 Years",{"count":77,"type":19},126,[22],"Medically complex older Veterans are at greater risk for progressive declines in physical function, lower quality of life, and increasing care needs. Additionally, older Veterans experience social isolation and loneliness, and have low levels of physical activity. While the Veterans Health Administration has established programs to address rehabilitation needs, these programs tend to be diagnosis-focused, lack self-management approaches, include low-intensity rehabilitation, and typically require in-person attendance. A MultiComponent TeleRehabilitation (MCTR) program that includes high-intensity rehabilitation and self-management interventions, social support, and telehealth and technology supports may be more effective in improving and sustaining physical function for older Veterans with complex health conditions. Therefore, this project is designed to determine whether the MCTR program improves strength and physical function more effectively than traditional interventions.",[81,25],"Multimorbidity",[83,84,85,86,87],"telerehabilitation","high intensity","biobehavioral","social support","physical activity","RECRUITING","2026-02-20",{"date":91,"type":36},"2026-02-24",{"date":93,"type":36},"2024-04-18",{"date":95,"type":19},"2028-03-31",{"name":42,"class":43}]