[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"physiology\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:physiology":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100392549","assessment-of-the-relationship-between-cerebral-blood-flow-and-heart-rate-100392549",false,"NCT04391465","Assessment of the Relationship Between Cerebral Blood Flow and Heart Rate","Assessment of the Relationship Between Cerebral Blood Flow and Heart Rate: An Electrophysiology Based Study","Inclusion Criteria:\n\n* Male or female\n* Age 18-70 years, inclusive\n* Scheduled for clinically indicated elective electrophysiological studies where temporary pacing catheters are being placed in the right atrium\n* Left ventricular ejection fraction ≥50%\n* Able and willing to provide informed consent\n* Able to travel to the Cardiac Electrophysiology Laboratory at the Foothills Medical Centre, Calgary, Alberta, Canada\n\nExclusion Criteria:\n\n* Unable or unwilling to provide informed consent\n* Other factors which in the investigator's opinion would prevent the participant from completing the protocol","ALL","18 Years","70 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","The investigators will seek to determine the relationship between heart rate and middle cerebral artery (MCA) cerebral blood flow (CBF), as well as better understand the hemodynamic determinants of MCA CBF velocity. In order to manipulate heart rate, the investigators will recruit patients already scheduled for clinically indicated elective electrophysiological studies, where temporary pacing catheters placed in the right atrium can be used to artificially pace the heart at controlled rates. MCA CBF will be measured by transcranial Doppler ultrasound.",[27,28],"Cerebrovascular Circulation","Physiology",[30],"Cerebral Blood Flow","RECRUITING","2026-04-30",{"date":34,"type":35},"2026-05-07","ACTUAL",{"date":37,"type":35},"2021-08-11",{"date":39,"type":21},"2027-12",{"name":41,"class":42},"University of Calgary","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":17,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":43},"100582526","breastfeeding-relaxation-intervention-among-mothers-of-preterm-infants-in-hospital-sultan-abdul-aziz-shah-hsaas-100582526","NCT06864455","Breastfeeding Relaxation Intervention Among Mothers of Preterm Infants in Hospital Sultan Abdul Aziz Shah (HSAAS)","\"Effects of a Relaxation Intervention on Physiological and Psychological Outcomes Among Mothers of Preterm Infants At Hospital Sultan Abdul Aziz Shah : a Within-subject Randomized Trials\"","Inclusion Criteria ( Mothers)\n\n* Malaysian women of reproductive age (18-49 years)\n* Muslim\n* Non-smoker\n* Understand English or Malay\n* Currently breastfeed their infants\n* Mothers of infants born in gestational age (28 weeks- 35 weeks)\n* No medical conditions that can affect infant feeding.\n\nExclusion Criteria:\n\n* Taking psychiatric medication and being diagnosed with mental illness.\n* Mothers are on medication that contradicts breastfeeding (eg: under medication HIV\u002FAIDS)\n* Plan to formula feed or mix feeding their infants.\n* Mothers of infants with illness that could affect breastfeeding and growth (respiratory issues, gastrointestinal issues, feeding difficulties, neurological disorder, etc)",true,"FEMALE","49 Years",{"count":55,"type":21},15,[24],"This study is designed to compare the effects of four relaxation interventions on both physiological and psychological outcomes in lactating mothers of preterm infants. The interventions being tested include:\n\n* Guided Imagery Meditation (GIM)\n* Religious Recitation (RR)\n* Infant Video with Music\n* Distraction with News and Media\n* A Control session\n\nThe primary objectives of the study are to evaluate and compare how these different relaxation techniques influence the physiological and psychological well-being of mothers and identify which intervention is most effective for lactating mothers who deliver prematurely.\n\nThe main research questions are:\n\n1. How do different interventions (GIM, RR, Infant Video with Music, Distraction with Media, and Control) affect physiological and psychological outcomes when measured within the same participants?\n2. Are there significant differences in physiological and psychological outcomes when participants are exposed to different interventions (GIM, RR, Infant Video with Music, Distraction with Media, and Control) within the same group?\n3. Among the interventions, which one demonstrates the most beneficial effects on physiological and psychological outcomes within the same participants?\n\nStudy Design:\n\nEach participant will be exposed to five different sessions (one for each intervention), with a gap of 1-2 days between sessions. The interventions will be administered as follows:\n\n* Guided Imagery Meditation (GIM)\n* Religious Recitation (RR)\n* Infant Video with Music\n* Distraction with News and Media\n* A Control session\n\nExpected Outcomes:\n\nThis study will assess the following physiological and psychological outcomes:\n\nPhysiological changes:\n\n* Heart Rate (HR)\n* Systolic Blood Pressure (SBP)\n* Diastolic Blood Pressure (DBP)\n* Fingertip Temperature (FT)\n* Breast milk cortisol concentration\n\nPsychological changes:\n\n•. Perceived Relaxation",[59,60,28,61],"Behaviour","Psychology","Therapy","2025-03-03",{"date":64,"type":35},"2025-03-07",{"date":66,"type":35},"2024-09-17",{"date":68,"type":21},"2026-08-21",{"name":70,"class":42},"Universiti Putra Malaysia"]