[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"picc-line-placement\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:picc-line-placement":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100637233","effects-of-different-tunnel-methods-in-picc-catheterization-100637233",false,"NCT07594704","Effects of Different Tunnel Methods in PICC Catheterization","Effects of Different Tunnel Methods in PICC Catheterization: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged between 18 and 75 years old;\n* Educational level of primary school or above, with basic listening, speaking, reading and writing abilities, and capable of completing the questionnaire independently;\n* Receiving tunneled PICC catheterization for the first time, with 4Fr single-lumen solo PICC catheter indwelling;\n* Able to attend regular PICC maintenance at our hospital as scheduled after catheterization;\n* Voluntarily participate in this study and sign the informed consent form for this study as well as the informed consent form for PICC catheterization.\n\nExclusion Criteria:\n\n* Patients with coagulation dysfunction (INR \\> 1.5 \u002F PLT \\\u003C 50×10⁹\u002FL);\n* Pregnant or lactating women;\n* Patients with BMI \\\u003C 18.5 kg\u002Fm²;\n* Patients receiving PICC catheterization via lower extremity veins;\n* Patients with known or suspected allergy to components of PICC catheters.","ALL","18 Years","75 Years",{"count":20,"type":21},284,"ESTIMATED","INTERVENTIONAL",[24],"NA","This prospective randomized controlled trial compares the effectiveness and safety of one-needle and two-needle tunneling techniques for peripherally inserted central catheter (PICC) placement, aiming to identify the optimal tunneling method to reduce catheter-related complications.",[27,28],"PICC Line Placement","PICC-associated Thrombosis",[30,31,32,33,34,35],"tunnel","PICC","complications","thrombosis","infection","bleeding","RECRUITING","2026-05-18",{"date":39,"type":40},"2026-05-22","ACTUAL",{"date":42,"type":40},"2026-04-01",{"date":44,"type":21},"2026-07-30",{"name":46,"class":47},"Sun Yat-sen University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100628809","image-guided-central-catheter-insertion-with-concurrent-assessment-of-vascular-wall-integrity-100628809","NCT07466472","Image-Guided Central Catheter Insertion With Concurrent Assessment of Vascular Wall Integrity","Assessment of the Impact of a Peripherally Inserted Central Catheter on Vascular Wall Integrity","Inclusion Criteria:\n\n* sinus rhythm\n* medical indication\n* suitable upper-extremity venous anatomy confirmed by ultrasound examination\n* ability to provide written informed consent\n\nExclusion Criteria:\n\n* Implanted cardiac pacing device\n* Palliative care\n* \\\u003C18years old\n* Local infection, skin lesion, or burn at the intended insertion site\n* Severe coagulopathy contraindicating vascular access procedures\n* Known allergy to catheter materials or local anesthetics used during the procedure\n* Presenceof an implanted cardiac pacemaker or non-sinus cardiac rhythm preventing reliable intracavitary ECG guidance\n* Anatomical abnormalities preventing safe PICC insertion\n* Previous lymphadenectomy on the intended side\n* Pre-existing venous thrombosis or significant venous wall pathology detected on baseline ultrasound",{"count":57,"type":21},80,"OBSERVATIONAL","The insertion of peripherally inserted central catheters (PICCs) represents a minimally invasive and safe method for establishing long-term central venous access in patients requiring prolonged intravenous therapy, including chemotherapy, parenteral nutrition, and long-term antibiotic treatment. Ultrasound-guided cannulation of peripheral arm veins improves procedural success, reduces complications, and increases patient comfort compared with centrally inserted central catheters.Accurate positioning of the catheter tip at the cavo-atrial junction is essential for optimal catheter function and safety. The Sherlock 3CG Tip Confirmation System combines electromagnetic tracking with intracavitary electrocardiography (ECG) to enable real-time catheter tip navigation and positioning.The aim of this prospective clinical study is to evaluate the accuracy and safety of ultrasound-guided PICC insertion using the Sherlock 3CG system, as well as to assess the impact of PICC placement on venous wall integrity. Ultrasound examination of the target vein will be performed before catheter insertion and after catheter removal to evaluate potential vascular wall changes associated with catheter use. A chest X-ray examination will be performed after each catheter insertion to confirm final catheter tip position and to assess the accuracy of the navigation system.Fluoroscopic guidance will be used only in selected cases, such as patients with anatomical anomalies, previously known difficult vascular access, or unsuccessful standard catheter advancement.A total of 80 adult patients with a clinical indication for PICC placement will be enrolled over a three-year study period.",[27,61],"Vessels; Anomaly",[31,63,64,65,66],"Sherlock 3CG","Vessels Anomaly","Vessel Wall","Intracavitary Electrocardiogram","NOT_YET_RECRUITING","2026-03-09",{"date":70,"type":40},"2026-03-12",{"date":42,"type":21},{"date":73,"type":21},"2029-08-01",{"name":75,"class":47},"University Medical Centre Ljubljana"]