[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pilates-exercise\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pilates-exercise":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":37,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":4},"100631702","the-effect-of-remotely-delivered-pilates-on-physical--and-psychological-outcomes-in-individuals-with-multiple-sclerosis-100631702",false,"NCT07504120","The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis","Does Remotely Delivered Pilates Influence Physical and Psychological Outcomes in Individuals With Multiple Sclerosis?","MS","Inclusion Criteria:\n\n* Age 18 years or older\n* Self-reported diagnosis of multiple sclerosis by a neurologist\n* Relapse-free for the past 30 days before screening\n* Able to speak and read English as the primary language\n* Access to the internet and e-mail,\n* Ability to use Zoom, and willingness to complete testing sessions and questionnaires\n* Ambulatory without an assistive device (for example, cane)\n* Low to moderate disability, defined as a score of 0-4 on the Patient-Determined Disease Steps (PDDS)\n* Insufficiently active, defined as a score \\\u003C 14 on the Godin Leisure-Time Exercise Questionnaire-Health Contribution Score (GLTEQ-HCS)\n* Adequate visual ability and literacy to read materials printed in 14-point font\n* Currently treated with a disease-modifying therapy\n\nExclusion Criteria:\n\n* Pregnant\n* Elevated risk for strenuous or maximal exercise, defined as more than one \"Yes\" response on the Physical Activity Readiness Questionnaire (PAR-Q) during screening","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","Objectives Objective 1: To determine the effects of a 16-week remotely delivered Pilates intervention on walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.\n\nObjective 2: To examine the impact of a 16-week remotely delivered Pilates intervention on depression \\& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.\n\nAim Aim 1: To assess whether the 16-week remotely delivered Pilates intervention significantly improves walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS Aim 2: To investigate whether the 16-week remotely delivered Pilates intervention significantly improves depression \\& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.\n\nHypothesis Hypothesis 1: The 16-week remotely delivered Pilates intervention will significantly improve walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.\n\nHypothesis 2: Participants receiving the 16-week remotely delivered Pilates intervention will demonstrate significantly greater improvements in depression \\& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.",[27,28,29,30,31,32,33,34,35,36],"Multiple Sclerosis","Pilates Exercise","Walking","Balance","Fatigue in Multiple Sclerosis","Pain Management","Quality of Life","Depression","Cognition","Fatigue",[38,39,36,35,40,29,34,30,41],"multiple sclerosis","Pilates","Quality of life","Pain","NOT_YET_RECRUITING","2026-03-25",{"date":45,"type":46},"2026-03-31","ACTUAL",{"date":48,"type":21},"2026-06-01",{"date":50,"type":21},"2027-12-01",{"name":52,"class":53},"University of Illinois at Chicago","OTHER",{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":4,"studyType":22,"phases":66,"briefSummary":67,"conditions":68,"keywords":73,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":88},"100618669","impact-of-pilates-exercises-on-bone-mineral-density-in-breast-cancer-survivors-receiving-hormonal-therapy-100618669","NCT07334626","Impact of Pilates Exercises on Bone Mineral Density in Breast Cancer Survivors Receiving Hormonal Therapy","PilatesBCS2026","Inclusion Criteria:\n\n1. Female breast cancer survivors aged 40-60 years.\n2. Histologically confirmed stage I-III breast cancer.\n3. Currently receiving hormonal therapy (aromatase inhibitors) for at least 3 months.\n4. At risk of osteoporosis or with low bone mineral density (BMD) defined by T-score ≤ -1.0 at lumbar spine or hip.\n5. Medically cleared for exercise, specifically low-to-moderate intensity Pilates.\n6. Able to attend supervised exercise sessions three times per week for 12 weeks.\n7. Willing and able to provide written informed consent.\n\nExclusion Criteria:\n\n1. Metastatic (stage IV) or recurrent breast cancer.\n2. History of osteoporotic fractures in the past 12 months.\n3. Severe cardiovascular, respiratory, or musculoskeletal conditions that contraindicate exercise.\n4. Uncontrolled hypertension, diabetes, or thyroid disorders.\n5. Current use of corticosteroids.\n6. Active bone metabolic disease other than osteoporosis (e.g., Paget's disease, osteomalacia).\n7. Severe cognitive impairment or psychiatric illness preventing adherence to exercise or supplementation.\n8. Known allergy or intolerance to calcium or vitamin D supplementation.\n9. Participation in another clinical trial with structured exercise or bone-targeted intervention within the last 3 months.","FEMALE","40 Years","60 Years",{"count":65,"type":21},60,[24],"Breast cancer survivors receiving endocrine (hormonal) therapy (aromatase inhibitors) are at high risk for cancer treatment-induced bone loss and osteoporosis due to estrogen depletion.",[69,70,71,72,28],"Breast Cancer","Breast Cancer Survivors","Aromatase Inhibitors","Osteoporosis or Osteopenia",[74,75,76,77],"pilates exercises","breast cancer survivors","bone mineral denisty","aromatase inhibitors","RECRUITING","2026-01-14",{"date":81,"type":46},"2026-01-15",{"date":83,"type":46},"2026-01-01",{"date":85,"type":21},"2026-09-30",{"name":87,"class":53},"Benha University",1]