[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pilonidal-sinus-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pilonidal-sinus-disease":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100625270","silac-versus-phenol-for-the-treatment-of-pilonidal-sinus-disease-a-randomized-controlled-trial-100625270",false,"NCT07420452","Silac Versus Phenol for the Treatment of Pilonidal Sinus Disease: A Randomized Controlled Trial","Comparison of Silac and Phenol Treatments in Primary Pilonidal Sinus Disease: A Prospective Randomized Controlled Trial With 6-Month Follow-up","SILPHEN26","Inclusion Criteria:\n\n* Age between 18 and 64 years\n* Diagnosis of primary pilonidal sinus disease\n* Maximum of three sinus openings (pits)\n* History of no more than two previous abscess episodes\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Recurrent or previously operated pilonidal sinus disease\n* More than three sinus openings\n* More than two previous abscess episodes\n* Acute abscess requiring emergency drainage at presentation\n* Presence of significant uncontrolled comorbidities\n* Pregnancy\n* Inability to comply with follow-up","ALL","18 Years","64 Years",{"count":21,"type":22},200,"ESTIMATED","INTERVENTIONAL",[25],"NA","Pilonidal sinus disease is a common condition affecting young adults and is associated with pain, infection, and reduced quality of life. Various minimally invasive treatment options have been developed to reduce recurrence and improve recovery time. Among these methods, Silac (laser ablation) and phenol application are frequently used techniques.\n\nThe aim of this prospective randomized controlled trial is to compare the effectiveness and safety of Silac and phenol treatments in patients with primary pilonidal sinus disease. Eligible patients will be randomly assigned to receive either Silac or phenol treatment. The primary outcome of the study is recurrence rate. Secondary outcomes include postoperative pain, healing time, time to return to work, patient satisfaction, and treatment cost.\n\nPatient recruitment is planned over a 6-month period, and each participant will be followed for 6 months after treatment. The total study duration will be 12 months. The results of this study are expected to provide evidence to guide the selection of minimally invasive treatment options for primary pilonidal sinus disease.",[28],"Pilonidal Sinus Disease",[28,30,31,32],"SiLac","Phenol","Sacrococcygeal Pilonidal Sinus","NOT_YET_RECRUITING","2026-02-12",{"date":36,"type":37},"2026-02-19","ACTUAL",{"date":34,"type":22},{"date":40,"type":22},"2026-12-31",{"name":42,"class":43},"Izmir City Hospital","OTHER_GOV",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":44},"100624344","the-effect-of-local-anesthesia-techniques-on-postoperative-pain-after-laser-treatment-of-pilonidal-sinus-100624344","NCT07408414","The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal Sinus","Procjena Postoperativne Boli Konvencionalnom i Tumescentnom Anestezijom u Laserskom Tretmanu Pilonidalnog Sinusa","Inclusion Criteria:\n\n* Diagnosed pilonidal sinus disease\n* Laser treatment for pilonidal sinus disease\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Recurrent pilonidal sinus\n* Chronic pain syndrome\n* Prisoners",{"count":53,"type":22},100,[25],"\"Assessment of postoperative pain with conventional and tumescent local anesthesia in the laser treatment of pilonidal sinus.\"\n\nThe aim of this study is to:\n\nexamine the possible difference in postoperative pain between two local anesthesia procedures after laser treatment of pilonidal sinus disease on the first and second postoperative day, as well as one week after surgery.\n\nDuring the procedure, two well-established anesthesia techniques are used to make the surgical area painless.\n\nThe first is local anesthesia, in which the anesthetic is injected into and under the skin.\n\nThe second procedure is tumescent anesthesia. In this procedure, the anesthetic in diluted form is introduced into the subcutaneous tissue. Both procedures are used in surgery and are standard methods of local anesthesia.",[57,28,58,59],"Pilonidal Cyst and Sinus Without Abscess","Pilonidal Sinus Treatment","Laser Ablation",[61,62,63,64,65,66,67],"PSD","Tumescent local anesthesia","Pilonidal sinus","Sinus laser-assisted closure","Tumescent technique","Laser treatment","Laser therapy","RECRUITING","2026-02-10",{"date":71,"type":37},"2026-02-13",{"date":73,"type":37},"2025-09-04",{"date":75,"type":22},"2027-09-30",{"name":77,"class":78},"Opća županijska bolnica Požega","OTHER",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":23,"phases":89,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":44},"100594784","effect-of-phenol-addition-to-laser-treatment-on-epithelialization-and-healing-process-in-pilonidal-sinus-100594784","NCT07023952","Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus","Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus: A Prospective Randomized Controlled Clinical Trial","PLEPS","Inclusion Criteria:\n\n* Age 18 years and older\n* Primary pilonidal sinus disease\n* Three or fewer pit counts\n* Willing to participate in the study and signed informed consent form\n* Able to attend follow-up visits\n\nExclusion Criteria:\n\n* Age under 18 years\n* More than three pit counts\n* Acute abscess presentation\n* Bilateral lateral extension\n* Recurrent pilonidal sinus disease\n* Immunocompromised patients\n* Patients unable to attend follow-up visits\n* Pregnancy (if applicable)\n* Severe comorbidities that contraindicate surgery under local anesthesia",{"count":88,"type":22},130,[25],"This study compares two treatment approaches for pilonidal sinus disease: laser treatment alone versus laser treatment combined with phenol application. Pilonidal sinus is a common condition that affects young adults and can cause significant discomfort and time off work.\n\nParticipants will be randomly assigned to receive either laser treatment only (Group A) or laser treatment plus phenol application (Group B). Both treatments are minimally invasive and performed under local anesthesia as day surgery procedures.\n\nThe main goal is to determine if adding phenol to laser treatment speeds up the healing process (epithelialization) and improves patient outcomes. We will measure healing time, pain levels, return to daily activities, and quality of life over a 3-month follow-up period.\n\nThis research may help develop more effective treatment protocols that reduce healing time and improve patient comfort for people with pilonidal sinus disease.",[28,92],"Laser Therapy",[94,95],"Minimally Invasive Treatment","Day Surgery","2025-06-14",{"date":98,"type":37},"2025-06-17",{"date":100,"type":37},"2025-05-01",{"date":102,"type":22},"2025-11-01",{"name":104,"class":78},"Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital"]