[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pit-and-fissure-sealant\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pit-and-fissure-sealant":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100572170","phase-4-resin-infiltrate-as-pit-and-fissure-sealant-in-permanent-molars-100572170",false,"NCT06729788","Resin Infiltrate as Pit and Fissure Sealant in Permanent Molars","Evaluation of Resin Infiltrate as Pit and Fissure Sealant in Permanent Molars (In Vivo& In Vitro)","Inclusion Criteria:\n\n1. Age of the children from 6 to 8 years.\n2. Healthy children free from any systemic disease.\n3. Show bilaterally sound fully erupted lower first permanent molars with deep narrow central fissures and supplemental grooves.\n4. The eruption time of these molars should not exceed 3 years.\n5. No sign of pain or active periodontal disease in the selected teeth.\n\nExclusion Criteria:\n\n1. Children with fillings or sealants in the selected teeth.\n2. Children with clinical evidence of caries in the selected teeth either white spot lesions or cavities.\n3. Children with an allergy to any drug, such as resin restorative material.\n4. Children with Extremely poor oral hygiene.\n5. Hypoplastic teeth.\n6. Children with bruxism.",true,"ALL","6 Years","8 Years",{"count":21,"type":22},86,"ESTIMATED","INTERVENTIONAL",[25],"PHASE4","The aim of this study is to evaluate and compare the clinical effectiveness of ICON resin Infiltration versus conventional sealant and the microleakage and penetration depth of the two sealant materials.",[28,29,30],"Resin Infiltration","Pit and Fissure Sealant","Permanent Molars","NOT_YET_RECRUITING","2024-12-09",{"date":34,"type":35},"2024-12-11","ACTUAL",{"date":37,"type":22},"2025-01-04",{"date":39,"type":22},"2025-12-24",{"name":41,"class":42},"Tanta University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100554042","phase-2-clinical-efficiency-of-bioactive-pit-and-fissure-sealant-100554042","NCT06493942","Clinical Efficiency of Bioactive Pit and Fissure Sealant","Clinical Evaluation of Bioactive Versus Filled Resin Based Pit & Fissure Sealants in First Permanent Molars: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Inclusion Criteria of participants:\n\n  * Patients with caries susceptible fiss- ures in fully erupted first permanent molars showing nosigns of caries.\n  * Co-operative patients approving to part- icipate in the trial.\n  * Good oral hygiene.\n* Inclusion Criteria of teeth:\n\n  * Caries susceptible occlusal pits and fissures.\n  * Intact contact with opposing teeth.\n  * Teeth with no previous restorations in other surfaces.\n\nExclusion Criteria:\n\n* Exclusion criteria of participants:\n\n  * patients with Disabilities, systemic disease or severe medical complications.\n  * patients have allergic history concerning methacrylate.\n  * patients with rampant caries, xerostomia, evidence of severe bruxism, clenching, or tempromandibular joint disorders\n  * participants who show lack of compliance.\n* Exclusion criteria of teeth:\n\n  * Carious pits and fissures.\n  * Developmental tooth defect.\n  * Partially erupted teeth\n  * Periapical pathology or signs of pulpal pathology.\n  * Tooth hypersensitivity.\n  * Heavy occlusion and occlusal contacts.","10 Years",{"count":53,"type":22},40,[55],"PHASE2","This study will compare the performance of newly introduced bioactive resin based pits and fissure sealant versus fluoride releasing filled resin based pits and fissure sealant in posterior molars prone to carious lesions of fissures in patients at risk of caries. Visual tactile examination and VistaCAM will be used for evaluation.",[29],[59,60,61,62,63,64,65,66],"dental sealant","pit and fissure sealant","fissure sealant","Bioactive dental sealant","Tooth sealant","Fissure sealants","Dental sealants","Pit sealants","2024-07-02",{"date":69,"type":35},"2024-07-10",{"date":71,"type":22},"2024-08-01",{"date":73,"type":22},"2025-09-30",{"name":75,"class":42},"Cairo University"]