[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"plantar-fasciopathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:plantar-fasciopathy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,52,76,108,142],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100638228","barefoot-walking-vs-standardised-conservative-care-for-plantar-fasciopathy-100638228",false,"NCT07600229","Barefoot Walking VS Standardised Conservative Care for Plantar Fasciopathy","Clinical and Economic Effectiveness of Barefoot Walking Compared to Standardised Conservative Care for the Treatment of Plantar Fasciopathy: a Pragmatic Randomised Controlled Trial","Inclusion Criteria:\n\n* Aged 18-70 years;\n* Clinical diagnosis of Plantar Fasciopahty, defined by: a) Pain localised to the medial calcaneal tubercle of sharp or stabbing quality; b) Pain worst with the first few steps in the morning or after a period of rest (first-step pain); c) Pain reproduced with palpation of the medial calcaneal tubercle OR positive Windlass Test;\n* Symptom duration greater than 4 weeks;\n* Able to walk independently without a mobility aid\n* Able to provide informed consent and comply with study protocol\n\nExclusion Criteria:\n\n* Prior surgery on the affected foot\n* Diabetes with peripheral neuropathy or other neurological condition affecting lower limb sensation or motor control\n* Active inflammatory arthropathy, uncontrolled vascular disease, or inability to walk unaided\n* Current or recent (less than 6 months) bony stress fracture or other acute foot or ankle injury on the affected side\n* Pregnancy during the intervention period\n* BMI greater than 40 kg\u002Fm²\n* Corticosteroid injection to the affected foot within the previous 3 months\n* Night splints initiated less than 4 weeks prior to enrolment\n* Any condition that would make participation unsafe, including open foot wounds","ALL","18 Years","70 Years",{"count":20,"type":21},74,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn if a barefoot walking programme can treat plantar fasciopathy (heel pain) in adults aged 18-70. The main questions it aims to answer are:\n\n* Does a barefoot walking programme reduce heel pain compared to a standardised stretching and strengthening programme?\n* Does a barefoot walking programme improve foot function and quality of life in adults with plantar fasciopathy?\n\nResearchers will compare a barefoot walking programme to a standardised stretching and strengthening programme to see if barefoot walking is an effective conservative management approach for plantar fasciopathy.\n\nParticipants will:\n\n* Be randomly assigned to either a barefoot walking programme or a stretching and strengthening programme\n* Complete a 12-week home-based exercise programme\n* Complete short weekly questionnaires throughout the 12 weeks\n* Complete 3 follow-up surveys over 6 months after the intervention ends\n* Receive education on load management and plantar fasciopathy",[27,28,29,30],"Plantar Fasciopathy","Plantar Fasciitis","Plantar Fasciitis, Chronic","Heel Pain",[32,33,34,35,36,37,38],"Plantar fasciopathy","Plantar fasciitis","Heel pain","Barefoot walking","Foot pain","Musculoskeletal","Physical therapy","RECRUITING","2026-05-20",{"date":42,"type":43},"2026-05-22","ACTUAL",{"date":45,"type":43},"2026-05-07",{"date":47,"type":21},"2027-10-31",{"name":49,"class":50},"Elisabetta Brigo","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":51},"100575612","early-implementation-of-plyometric-exercises-in-the-rehabilitation-of-individuals-suffering-from-lower-extremity-tendinopathies-100575612","NCT06774547","Early Implementation of Plyometric Exercises in the Rehabilitation of Individuals Suffering From Lower-Extremity Tendinopathies","The Efficacy of Early Implementation of Plyometric Exercises in the Rehabilitation of Individuals Suffering From Lower-Extremity Tendinopathies: A Randomised Clinical Trial","Inclusion Criteria:\n\n1. participants are required to have performed either recreational running or participated in sports that include running or jumping activities (e.g., football, basketball, handball, volleyball) at least once per week for at least three months immediately prior to pain onset\n2. have had symptoms for at least three months\n3. have pain\u002Fsoreness with palpation of the tendon\u002Ffascia\n4. mean pain during the past week of at least 2 on a 0 to 10 Numerical Rating Scale\n5. pain during a pain provocation test (patellar tendinopathy: five single-legged decline squats, Achilles tendinopathy and plantar fasciopathy: ten single-legged heel raises)\n\nExclusion Criteria:\n\n1. previous lower-extremity surgery\n2. other lower-extremity musculoskeletal conditions that have required treatment by a healthcare professional during the past three months\n3. pregnancy\n4. diabetes\n5. history of inflammatory systemic diseases (e.g., rheumatoid arthritis or spondylarthritis)\n6. having received an injection with corticosteroid within the past six months.","50 Years",{"count":61,"type":21},120,[24],"This clinical trial aims to compare the effectiveness of an early plyometric exercise approach with traditional heavy, slow resistance training in treating tendinopathies of the Achilles tendon, patellar tendon, and plantar fascia. These conditions, commonly seen in general and rheumatology practices, cause pain, reduced function, and stiffness, often leading to prolonged recovery and incomplete return to full physical activity. The study hypothesizes that introducing plyometric exercises early in rehabilitation will improve jump function after 12 weeks and reduce re-injury rates within 52 weeks compared to traditional methods.\n\nThe study is a randomized clinical trial including 120 participants aged 18-50 with tendinopathy in one of the targeted areas. Participants must regularly engage in running or jumping sports, have symptoms for at least three months, and meet other inclusion criteria. Exclusion criteria include recent surgery or specific medical conditions. Both groups will perform exercises three times weekly for 12 weeks, tailored to their tendinopathy. The intervention group will add progressive plyometric exercises to the standard strength training performed by the control group. Plyometric training will consist of three levels, with patients self-assessing readiness to progress.\n\nThe primary outcome is the change in the plyometric quotient, a measure of functional ability, based on a jump test using a force platform at 0 and 12 weeks. Secondary outcomes include dynamic strength, jump height, patient-reported symptoms (via questionnaires), return to sport, training compliance, adverse events, pain thresholds, re-injury rates, and psychological readiness for sports. Assessments will occur at baseline, 12 weeks, and 52 weeks.",[65,66,27],"Achilles Tendinopathy","Patellar Tendinopathy","2026-03-02",{"date":69,"type":43},"2026-03-04",{"date":71,"type":43},"2025-09-18",{"date":73,"type":21},"2028-01",{"name":75,"class":50},"Aalborg University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":51},"100610443","phase-2-nac-repair-for-post-surgical-pain-100610443","NCT07227649","NAC-REPAIR for Post-surgical Pain","NAC-REPAIR: N-Acetylcysteine-facilitated Redox-Immune Modulation for Post-surgical Analgesia and Injury Recovery","Inclusion Criteria:\n\n* Elective outpatient hand\u002Fupper-extremity or foot\u002Fankle surgery (single site; same-day discharge)\n* Baseline visit feasible ≤14 days pre-op\n* Can complete surveys\u002Fblood draw\n* Provides informed consent\n* Willing to follow dosing schedule and avoid restricted supplements\u002Fmeds\n\nExclusion Criteria:\n\n* Allergy to NAC\u002Fcapsule components □ NAC or high-dose antioxidants in past 14 days (unwilling to stop)\n* Chronic daily opioids ≥3 months or OUD\u002Fmaintenance therapy □ Pregnant\u002Fbreastfeeding or no contraception as applicable\n* Daily nitrates (nitroglycerin\u002Fisosorbide) □ Planned \\>24h admission, multistage\u002Ftrauma case □ Other interventional study within 30 days\n* Unable to swallow capsules \u002F malabsorption surgery affecting oral meds","75 Years",{"count":85,"type":21},80,[87],"PHASE2","This pilot asks whether peri-operative N-acetylcysteine (NAC) improves recovery after common outpatient hand\u002Ffoot-ankle surgery-specifically, does NAC reduce pain and opioid use and enhance function by modulating redox-inflammatory pathways? Primary objectives are to establish feasibility (accrual, adherence, follow-up), estimate NAC vs placebo effects on pain, function, and opioid consumption, and characterize inflammatory signatures that may predict response.\n\nMethods: a single-site, double-blind, 1:1 randomized trial (N≈80) comparing NAC 1,200 mg twice daily for 14 days (starting pre-op) vs matching placebo; daily e-diaries for POD0-14; standardized outcomes (PROMIS Pain Interference; QuickDASH or FAAM; PGIC; opioid MME); and small blood draws pre-surgery and at two follow-up visits for cytokine profiling.",[90,91,92,93,94,95,96,27,97],"Carpal Tunnel Surgery","Trigger Finger Disorder","De Quervain Syndrome","Guyon's Canal","Dupuytren Contracture","Morton Neuroma","Tarsal Tunnel Syndrome","Peroneal Nerve Entrapment","NOT_YET_RECRUITING","2025-11-12",{"date":101,"type":43},"2025-11-14",{"date":103,"type":21},"2026-01-15",{"date":105,"type":21},"2027-07-15",{"name":107,"class":50},"University of Arizona",{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":115,"enrollmentInfo":116,"targetDuration":4,"studyType":22,"phases":118,"briefSummary":119,"conditions":120,"keywords":125,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":51},"100602184","one-cause-of-heel-pain-is-plantar-fasciopathy-pf-in-most-cases-a-heel-spur-is-frequently-present-alongside-pf-we-aim-to-evaluate-the-efficacy-of-corticosteroid-injection-and-radiofrequency-ablation-along-with-tissue-elasticity-assessed-by-ultrasound-in-patients-with-chronic-pain-6-months-100602184","NCT07120204","One Cause of Heel Pain is Plantar Fasciopathy (PF). In Most Cases, a Heel Spur is Frequently Present Alongside PF. We Aim to Evaluate the Efficacy of Corticosteroid Injection and Radiofrequency Ablation, Along With Tissue Elasticity Assessed by Ultrasound, in Patients With Chronic Pain (≥6 Months).","Evaluation of Radiofrequency Thermocoagulation Versus Corticosteroid Injection in Patients With Chronic Calcaneal Spur Related Plantar Fasciopathy Using Elastography and Foot Function Index","Inclusion Criteria:\n\n1. Patients with chronic (≥ 6 months) plantar fasciopathy\n2. NRS score ≥ 4\n3. Presence of a calcaneal spur detected by ultrasound (USG) or direct radiography\n4. At least one of the following treatments has been administered:\n\n   * Home exercise program\n   * Physiotherapy\n   * Orthosis\u002Fprosthesis\n   * NSAIDs\n   * Night splint\n   * Kinesio taping\n   * Corticosteroid injection\n   * Extracorporeal shock wave therapy (ESWT)\n\nExclusion Criteria:\n\n1. History of calcaneal trauma\u002Ffracture\n2. Previous radiofrequency ablation (RFA) treatment\n3. Patients with seronegative spondyloarthropathy\n4. Inflammatory or degenerative arthropathies\n5. Presence of diabetes\n6. Pregnancy\n7. History of cancer\n8. Peripheral neuropathy or ischemia\n9. Open wound or signs of infection at the procedure site\n10. Evidence of systemic infection\n11. Patients using anticoagulant or antiplatelet agents\n12. Presence of an intracardiac defibrillator or pacemaker\n13. Patients with tarsal tunnel syndrome\n14. Patients who have received ESWT and\u002For corticosteroid injection within the last 3 months\n15. Presence of heel pain due to lumbar radiculopathy","80 Years",{"count":117,"type":21},50,[24],"Heel pain is common among adults. One cause of heel pain is plantar fasciopathy (PF). In most cases, a heel spur, a bony prominence that extends into the plantar fascia, is frequently present alongside PF. First-line treatments include pain-relieving drugs, home exercises, heel support peds, and physical therapy. However, some patients can't get relief from these therapies, and the pain persists beyond six months. This situation is referred to as refractory chronic PF. Local treatments applied via skin puncture such as anti-inflamtory injection and destruction of nerves carrying pain signals to brain are warranted in these cases. We aim to evaluate the efficacy of corticosteroid injection and radiofrequency ablation, along with tissue elasticity assessed by ultrasound, in patients with chronic pain (≥6 months).\n\nThe goal of this clinical trial is to determine which treatment-corticosteroid injection or radiofrequency thermal thermocoagulation-is more effective for treating plantar fasciopathy in adults. It will also learn about the effects of the treatments on the properties of the heel tissue using ultrasound. The main questions it aims to answer are:\n\nDo corticosteroid injections and radiofrequency thermal thermocoagulation have the same efficacy on pain and functionality for both short- and long-term? Do corticosteroid injections and radiofrequency thermal thermocoagulation similarly affect heel tissue? The researchers will investigate which of the corticosteroid injection and radiofrequency thermocoagulation is more effective for",[27,121,122,123,124],"Chronic Pain","Corticosteroid Injection","Radiofrequency Ablation","Elasticity Imaging Techniques",[126,127,128,129,130,131,132],"plantar fasciopathy","plantar fasciitis","randomized","radiofrequency thermal coagulation","RF","shear wave","elastography","2025-08-06",{"date":135,"type":43},"2025-08-13",{"date":137,"type":21},"2025-08-15",{"date":139,"type":21},"2026-08-15",{"name":141,"class":50},"TC Erciyes University",{"id":143,"slug":144,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":147,"acronym":148,"eligibilityCriteria":149,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":59,"enrollmentInfo":150,"targetDuration":4,"studyType":22,"phases":152,"briefSummary":153,"conditions":154,"keywords":156,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":51},"100567671","effectiveness-of-infiltrations-in-the-treatment-of-plantar-fasciopathy-100567671","NCT06671223","Effectiveness of Infiltrations in the Treatment of Plantar Fasciopathy","Effectiveness of Infiltrations in the Treatment of Plantar Fasciopathy: A Randomized Clinical Study.","INFILTRA-PLANT","Inclusion Criteria:\n\nAge: Participants aged 18 to 50 years. Diagnosis: Confirmed diagnosis of plantar fasciopathy based on clinical evaluation and imaging (if applicable).\n\nDuration of Symptoms: Symptoms persisting for at least 6 weeks prior to enrollment.\n\nPain Level: Reported pain level of at least 4 on the Visual Analog Scale (VAS) at baseline.\n\nAbility to Comply: Participants must be able to follow study protocols and attend follow-up appointments.\n\nInformed Consent: Participants must provide written informed consent to participate in the study.\n\nExclusion Criteria:\n\nOther Foot Pathologies: Presence of other significant foot conditions (e.g., fractures, arthritis, tarsal tunnel syndrome) that could interfere with the study results.\n\nPregnancy or Breastfeeding: Pregnant or breastfeeding individuals will be excluded from the study.\n\nNeurological Disorders: History of significant neurological disorders affecting lower limb function.\n\nSystemic Conditions: Patients with systemic conditions (e.g., diabetes, autoimmune diseases) that could affect healing or response to treatment.\n\nAllergy to Corticosteroids: Known allergy or adverse reaction to corticosteroids or local anesthetics.\n\nPsychiatric Disorders: Individuals with severe psychiatric disorders that may impair their ability to provide informed consent or adhere to the study protocol.",{"count":151,"type":21},200,[24],"This clinical study aims to evaluate the effectiveness of infiltrations in the treatment of plantar fasciopathy, a painful condition that affects the sole of the foot and is common in active people. Plantar fasciopathy is caused by inflammation or damage to the plantar fascia, the tissue that connects the heel to the toes. Participants in this study will be randomly assigned to receive one of two treatments: corticosteroid infiltrations or conservative treatment without infiltrations. Infiltrations will be guided by ultrasound to ensure accuracy. The study will evaluate pain reduction and improvement in foot function over a six-month period. The objective of the study is to determine if infiltrations provide a significant improvement compared to other non-invasive treatments. The results will help doctors and patients make informed decisions about the best treatment options for plantar fasciopathy.",[155,27],"Plantar Fasciitis of Both Feet",[127,157,158,159,160,161,162],"fasciopaty","corticosteroid","PRP","hyaluronic acid","infiltrations","treatment","2024-10-31",{"date":165,"type":43},"2024-11-04",{"date":167,"type":21},"2025-06-01",{"date":169,"type":21},"2026-12-01",{"name":171,"class":50},"University of Seville"]