[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"plaque-accumulation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:plaque-accumulation":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100594224","phase-3-triphila-mouthwash-effect-as-anti-plaque-and-anti-gingivitis-in-children-100594224",false,"NCT07016659","Triphila Mouthwash Effect as Anti-plaque and Anti-gingivitis in Children","Assessing Antiplaque And Antigingivitis Efficacy Of Triphala Mouthwash Versus Chlorhexidine Mouthwash Among A Group Of Children: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients aged 9 to 13 years.\n* Apparently in good general health.\n* Both sexes.\n* Informed consent from their parents.\n* Patients with fair oral hygiene and gingival inflammation.\n* Participants should not have used mouthwashes for the follow-up period.\n\nExclusion Criteria:\n\n* Patients with known allergies to any ingredient used in the study.\n* History of immunosuppressive diseases.\n* History of antibiotic or anti-inflammatory therapy in the previous month till the start of the study.\n* Patients with orthodontic appliances.\n* Parents refused to participate or were unable to attend follow-up visits.",true,"ALL","9 Years","13 Years",{"count":21,"type":22},36,"ESTIMATED","INTERVENTIONAL",[25],"PHASE3","The study aim to to assess the antiplaque and antigingivitis efficacy of Triphala mouthwash versus chlorhexidine mouthwash among children.\n\nOral health, acknowledged as equally significant to general health, has become an essential component of an individual's entire well-being. Dental caries and periodontal problems are the two predominant oral conditions that repeatedly affect nearly all individuals throughout their entire lives (Sharma et al., 2014).\n\nNumerous bacterial communities can be found in the oral cavity. These bacteria are harmless if proper health is maintained and are a healthy part of the human microbiome; However, disturbances to the local or systemic environment can lead to opportunistic infections such as periodontitis, gingivitis, or cavities .\n\nIt has been known that dental plaque plays a critical role in the development and progression of periodontal disease, gingivitis, and dental caries. Plaque control is the first line of defense against periodontal disease and gingival inflammation, and chemical plaque control methods should always be used in conjunction with mechanical methods .\n\nPlaque removal is constantly maintained by mechanical techniques like toothbrushing and flossing, which are essential for controlling and preventing gingivitis, periodontitis, and dental caries. For mechanical plaque control, children need chemotherapeutic agents like therapeutic mouthwash since they lack the motivation or hand-eye coordination to reach the interproximal locations on their own.\n\nHerbal medicine takes a preventative and promotional strategy. It is an integrated approach that treats diseases and promotes health by using a variety of treatments made from plants and their extracts. The use of natural herbs such as Triphala, Tulsi Patra, Jyestiamadh, Neem, Clove Oil, Pudina, Ajwain, and many more, either alone or in combination, has been shown by research to be a safe and effective treatment for a variety of oral health issues, including mouth ulcers, bleeding gums, halitosis, and tooth decay prevention .\n\nTriphala, which exhibits antibacterial, antiseptic, and anti-inflammatory effects, is one of the most popular formulas in traditional Ayurvedic medicine. It is extensively used in dentistry and includes equal amounts of Terminalia Chebula, Terminalia Belerica, and Emblica Officinalis .\n\nTriphala comprises tannins that facilitate the physical removal of microorganisms by aggregating them. This reduces the quantity of bacteria adhering to teeth during the initial phases of plaque development. Triphala mouth rinse exhibits extensive antibacterial activity against both Gram-positive and Gram-negative pathogens. It also demonstrates antioxidant properties that aid in minimizing dental plaque and gingivitis. The tannic acid in Triphala may facilitate plaque reduction by binding to bacterial cell surfaces that denature proteins and eradicate bacterial cells.",[28,29],"Plaque Accumulation","Gingival Inflammation",[31,32,33,34],"triphila mouthwash","anti-plaque","anti-gingivitis","children","NOT_YET_RECRUITING","2025-06-05",{"date":38,"type":39},"2025-06-12","ACTUAL",{"date":41,"type":22},"2025-09-01",{"date":43,"type":22},"2026-10-01",{"name":45,"class":46},"Cairo University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":16,"sex":17,"minAge":19,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100559714","comparison-of-canine-retraction-using-ni-ti-closed-coil-springs-vs-elastomeric-power-chains-during-orthodontic-treatment-100559714","NCT06567730","Comparison of Canine Retraction Using Ni-ti Closed-coil Springs Vs Elastomeric Power Chains During Orthodontic Treatment","Comprehensive Comparison of Canine Retraction Using Nickel-titanium Closed-coil Springs Versus Elastomeric Power Chains During Orthodontic Treatment - A Split-mouth Randomized Controlled","Inclusion Criteria:\n\n* Patients aged between 13 - 40 years\n* Patients undergoing fixed orthodontic treatment\n* Patients requiring all first premolars extraction as part of orthodontic treatment\n* Patients with all permanent teeth present and erupted (except for second and third molars)\n* All patients who will sign the informed consent\u002Fassent form\n\nExclusion Criteria:\n\n* • Patients with systemic diseases that can affect tooth movements\n\n  * Patients with uncontrolled periodontal disease\n  * Patients with craniofacial syndromes\n  * Pregnant or lactating mothers\n  * Patients with bracket failures greater than three times per bracket during the study\n  * Patients on medications that can affect tooth movements\n  * Patients with Nickel allergy","40 Years",{"count":57,"type":22},46,[59],"NA","The objective of this study is to compare the canine retraction rate (in mm with a 100 mm marked scale) using Ni-Ti closed-coil springs versus elastomeric power chains during canine retraction in subjects with first premolar extractions over a period of three months.\n\nAfter the extraction of all first premolars under local anesthesia. For canine retraction, Ni-Ti closed-coil springs and elastomeric power chains will be randomly allocated to the right and left quadrants of both arches.\n\nRadiographic measurement (root resorption) and clinical measurements (canine retraction, plaque accumulation and gingival health) will be recorded at four points in time. First, at the start of the canine retraction (T0), after first month (T1), second month (T2) and third month follow-up (T3).",[62,28,63],"Root Resorption","Gingivitis",[65],"canine retraction rate","2025-01-28",{"date":68,"type":39},"2025-01-30",{"date":70,"type":22},"2025-03",{"date":72,"type":22},"2025-11",{"name":74,"class":46},"Munnal Gulzar"]