[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"plaque-induced-gingival-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:plaque-induced-gingival-disease":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100644455","phase-1-taste-acceptance-and-effectiveness-of-hyaluronic-acid-and-chlorhexidine-mouthwashes-in-children-with-gingivitis-100644455",false,"NCT07662226","Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With Gingivitis","Taste Acceptance and Clinical Effectiveness of Hyaluronic Acid Versus Chlorhexidine Mouthwashes in Children With Plaque-Induced Gingivitis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Children aged from 8-12 years of both sexes.\n* Children with a history of bleeding on brushing typical signs and symptoms of gingivitis.\n* Healthy child (ASA I).\n* Eruption of upper and lower permanent central and lateral incisors.\n* Parent's agreement to sign the informed consent.\n* Parent's ability for attending follow up visits.\n\nExclusion Criteria:\n\n* Children -allergic to Chlorhexidine or Hyaluronic acid.\n* Children with special health care needs or having a history of serious systemic disease that may affect the gingival health.\n* Use of Systemic NSAIDs, steroids, or antibiotics within a month before the study.\n* Children undergoing orthodontic treatment or having an intra-oral prosthesis.",true,"ALL","8 Years","10 Years",{"count":21,"type":22},32,"ESTIMATED","INTERVENTIONAL",[25],"PHASE1","This randomized controlled clinical trial aims to compare the taste acceptance and clinical effectiveness of hyaluronic mouthwash and chlorhexidine mouthwash in children with plaque-induced gingivitis. Clinical outcomes will be assessed using gingival and plaque indices, while taste acceptance will be evaluated using a validated hedonic scale. The findings may help identify a mouthwash that is both effective and acceptable to children, thereby improving adherence to oral hygiene practices.",[28],"Plaque Induced Gingival Disease",[30,31,32,33,34,35,36],"gingivitis","Chlorohexidine","Hyaluronic acid","Mouthwashe","Children","Taste acceptance","Palatability","NOT_YET_RECRUITING","2026-06-18",{"date":40,"type":41},"2026-06-23","ACTUAL",{"date":43,"type":22},"2026-08-01",{"date":45,"type":22},"2027-05-01",{"name":47,"class":48},"Cairo University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":16,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":63,"conditions":64,"keywords":69,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":49},"100583917","phase-3-efficacy-of-resveratrol-containing-mouthwash-in-reducing-halitosis-related-porphyrymonas-gingivalis-100583917","NCT06882564","Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.","Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyromonas Gingivalis: A Randomized, Triple-blind Clinical Trial","Inclusion Criteria:\n\n* Organoleptic tongue of scores \\> 2 using (0-5scale) (Rosenberg and McCulloch, 1992)\n* Male and female undergraduate dental students without chemical plaque control measures for at least one weak\n* Male and female students with halitosis due to gingivitis\n* The age of students ranges from 20 to 23 years.\n* No periodontal treatment for at least one month\n* No systemic disease\n* No tobacco smoking\n* The patients must have at least 20 teeth\n\nExclusion Criteria:\n\n* Smokers and alcoholics\n* Patient with periodontitis or pocket depth \\> 6mm\n* Patient with orthodontics appliance\n* Open carious lesions, pericoronitis, dry socket, and fistula.\n* Patients with systemic disease and condition\n* taking medication in the last two weeks\n* Take garlic, onion, or licorice in the last 24 hours\n* using oral hygiene products in the last 24 hours\n* pregnant women\n* sinusitis, tonsilitis, and upper respiratory tract infection","20 Years","24 Years",{"count":60,"type":22},54,[62],"PHASE3","The aim of the study:\n\nTo assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah University\u002FCollege of Dentistry and Wasit University \u002FCollege of Dentistry.\n\nObjectives:\n\n* To assess the efficacy of anti-oxidant and anti-inflammatory resveratrol mouthwash in reducing halitosis in undergraduate students with plaque-induced gingivitis patients.\n* To assess the efficacy of resveratrol mouthwash in reducing p. gingivalis in undergraduate students' patients with oral malodor.\n* To determine the relation between p.gingivalis and clinical periodontal parameters (plaque index, gingival index, bleeding on probing) among undergraduate students with plaque-induced gingivitis and halitosis.",[65,66,28,67,68],"Halitosis","Mouth Disease","Bleeding Gum","Peridontal Disease",[70,71,30,72,73],"halitosis","plaque","resveratrol","chlorhexidine","RECRUITING","2025-03-16",{"date":77,"type":41},"2025-03-18",{"date":79,"type":41},"2025-01-05",{"date":81,"type":22},"2025-11-01",{"name":83,"class":48},"Al-Mustansiriyah University",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":17,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":23,"phases":96,"briefSummary":98,"conditions":99,"keywords":100,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":4},"100570747","role-of-herbal-based-mouthwashes-in-plaque-control-100570747","NCT06711263","Role of Herbal Based Mouthwashes in Plaque Control","Role of Herbal Based Mouthwashes in Plaque Control. a Randomized Clinical Control Trial","mouthwash","Inclusion Criteria:\n\n* Patients who are medically fit\n* Patients with gingival inflammation not progressed into periodontitis (AAP classification\n* Patients between the age of 18-60 years\n\nExclusion Criteria:\n\n* Patients who are medically compromised\n* Patient who have undergone a periodontal therapy for the past 3 months\n* Patients who are healthy but have been using herbal mouthwashes","18 Years","60 Years",{"count":95,"type":22},80,[97],"NA","Herbal medicine has been used for thousands of years. Traditional herbal medicine is used by an estimated 80% of the world's population for primary health care. Herbal treatments have gained popularity as a dietary supplement for illness prevention and as an alternative\u002Fcomplementary therapy in recent years. Herbal remedies come in a wide variety of forms and can be found on the market all over the world.",[28],[71,101,72,102,103,73],"gingival bleeding","miswak","tea tree oil","2024-11-28",{"date":106,"type":41},"2024-12-02",{"date":108,"type":22},"2024-12-20",{"date":110,"type":22},"2025-03-20",{"name":112,"class":48},"Ajman University"]