[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pneumococcal-conjugate-vaccine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pneumococcal-conjugate-vaccine":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100413512","national-non-interventional-study-of-invasive-pneumococcal-disease-in-children-and-newborns-100413512",false,"NCT04664556","National, Non Interventional Study of Invasive Pneumococcal Disease in Children and Newborns","Population-based Nationwide Study on Invasive Pneumococcal Infections Among Children (0-18 Years) in France","IPD","Inclusion Criteria:\n\n* Isolate of Streptococcus pneumoniae from at least one blood culture, or pleural fluid, or joint fluid, or cerebrospinal fluid or other normally sterile body site, or if there is a positive blood polymerase chain reaction (PCR).\n\nExclusion Criteria:\n\n* Pneumococcal strain not transmetted to National Reference Center for Pneumococci or to Regional Pneumococci Observatory","ALL","1 Day","18 Years",{"count":21,"type":22},2500,"ESTIMATED","OBSERVATIONAL","After 7 then 13 valent pneumococcal conjugate vaccine (PCV) implementation in France in children, we will evaluate the impact of this vaccination on invasive pneumococcal disease (IPD). We will describe the clinical characteristics of IPD, pneumococcus serotyping, underlying conditions and vaccination status.",[26,27,28,29],"Pneumococcal Infections","Pneumococcal Conjugate Vaccine","Antibiotic Treatment","Mortality","RECRUITING","2026-04-23",{"date":33,"type":34},"2026-04-28","ACTUAL",{"date":36,"type":34},"2010-12-13",{"date":38,"type":22},"2030-01-01",{"name":40,"class":41},"Association Clinique Thérapeutique Infantile du val de Marne","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":50,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":60,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":64,"locationsCount":42},"100413513","national-bacterial-meningitis-study-in-children-and-newborns-100413513","NCT04664569","National Bacterial Meningitis Study in Children and Newborns","National Observatory of Bacterial Meningitis in Children and Newborns","Inclusion Criteria:\n\n* clinical signs of meningitis, associated with positive cerebrospinal fluid (CSF) culture and\u002For positive CSF antigen testing (Escherichia coli K1, N. meningitidis serogroups B, A, C, Y and W-135, group B streptococci, Hib, or S. pneumoniae), and\u002For positive CSF polymerase chain reaction (PCR), and\u002For positive blood culture with CSF pleocytosis (\\> 10 cells\u002FµL).\n* purpura fulminans\n\nExclusion Criteria:\n\n\\-",{"count":51,"type":22},10000,"Bacterial meningitis is a major cause of morbidity and mortality in childhood. Antibiotic treatment recommendations are based on epidemiological and susceptibility data. The epidemiology of bacterialméningitis has changed in recent years, mainly owing to widespread use of different conjugate vaccines. The aim of this prospective national survey is to describe epidemiology of bacteria implicated in bacterial meningitis in children.",[54,55,27,56,57,58,28,59],"Meningitis","Children, Only","Meningococcal Vaccines","H. Influenzae Vaccine","Neonatal Infection","Case Fatality Rate",{"date":33,"type":34},{"date":62,"type":34},"2001-01-01",{"date":38,"type":22},{"name":40,"class":41}]