[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pneumoperitoneum\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pneumoperitoneum":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,44,71,98,124,154,175,198,220],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100637976","pneumoperitoneum-pressure-and-lung-ultrasound-atelectasis-100637976",false,"NCT07609615","Pneumoperitoneum Pressure and Lung Ultrasound Atelectasis","Effects of Different Pneumoperitoneum Pressures on Perioperative Atelectasis Assessed by Lung Ultrasound in Laparoscopic Cholecystectomy: A Prospective Randomized Single-Blind Controlled Trial","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years\n* ASA physical status I-II\n* Scheduled for elective laparoscopic cholecystectomy under general anesthesia\n* Body mass index (BMI) \\\u003C30 kg\u002Fm²\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Chronic pulmonary disease\n* Recent respiratory tract infection\n* Thoracic deformity or previous thoracic surgery\n* Preoperative pulmonary pathology\n* Morbid obesity\n* Pregnancy\n* Emergency surgery\n* Conversion to open surgery\n* Requirement for protocol-violating pneumoperitoneum pressure modification\n* Refusal to participate in the study","ALL","18 Years","65 Years",{"count":20,"type":21},112,"ESTIMATED","INTERVENTIONAL",[24],"NA","Elective laparoscopic cholecystectomy may lead to perioperative atelectasis due to pneumoperitoneum-related diaphragmatic elevation and impaired respiratory mechanics. Lung ultrasound (LUS) provides a noninvasive bedside method for evaluating perioperative aeration loss. This prospective randomized controlled study aims to compare the effects of low-pressure (10 mmHg) and standard-pressure (14 mmHg) pneumoperitoneum on perioperative atelectasis assessed by LUS in patients undergoing laparoscopic cholecystectomy under general anesthesia. Changes in LUS scores, respiratory mechanics, oxygenation, and postoperative clinical outcomes will also be evaluated.",[27,28,29],"Atelectasis","Perioperative Complication","Pneumoperitoneum",[27,29,28],"RECRUITING","2026-06-22",{"date":34,"type":35},"2026-06-23","ACTUAL",{"date":37,"type":35},"2026-06-01",{"date":39,"type":21},"2026-09-01",{"name":41,"class":42},"Engin Çetin","OTHER_GOV",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":17,"maxAge":18,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":43},"100643680","maneuvers-to-reduce-laparoscopic-pain-100643680","NCT07583433","Maneuvers to Reduce Laparoscopic Pain","Optimal Maneuver to Reduce Postoperative Pain Following Elective Laparoscopic Surgeries","Inclusion Criteria:\n\n* Patients age 18 to 65\n* Benign, elective laparoscopic surgeries\n\nExclusion Criteria:\n\n* Ages \\\u003C18 and age \\>65\n* Emergency or urgent surgeries\n* Surgeries for chronic pelvic pain, malignancy\n* Surgeries during pregnancy\n* Severe cardiopulmonary disease\n* Prior extensive abdominal surgeries (more than 2 abdominal or pelvic surgeries)\n* Inability to consent",true,"FEMALE",{"count":54,"type":21},150,[24],"Laparoscopic surgery has revolutionized surgical care by reducing morbidity and improving post operative recovery. Laparoscopic surgery involves the use of carbon dioxide for insufflation to achieve optimal visualization. There is literature that demonstrates higher insufflation pressures being associated with increased postoperative pain - particularly shoulder pain - and opioid use. The ideal amount of intraperitoneal pressure is still under debate as other studies demonstrate that reduced pneumoperitoneum insufflation has also shown to negatively impact surgeon satisfaction and trended with longer operative time and greater blood loss without impacting pain.\n\nResidual intraperitoneal carbon dioxide can also contribute to postoperative discomfort. Studies have shown the effectiveness of various maneuvers in removing residual gas to reduce postoperative pain, such as intraperitoneal saline instillation, pulmonary recruitment, and gas aspiration via smoke evacuator.\n\nDespite these advantages, there is a lack of a clear consensus on the optimal method for reducing residual intraperitoneal gas. Conversely, literature has mixed results regarding the true significance in pain reduction.\n\nGiven the importance of minimizing postoperative pain, reducing opioid requirements, and shortening postoperative recovery time, the investigators propose a prospective, patient-blinded, randomized controlled trial. The investigators aim to investigate whether active gas removal via a smoke evacuator, multiple breath recruitment maneuvers, or no intervention would contribute to lowest postoperative pain. The findings will help identify the most effective method for reducing residual pneumoperitoneum-related pain and thus inform surgical practices and improve patient outcomes.",[58,59,29],"Laparoscopic Surgery","Post Operative Pain, Acute","NOT_YET_RECRUITING","2026-06-05",{"date":63,"type":35},"2026-06-09",{"date":65,"type":21},"2026-07-10",{"date":67,"type":21},"2028-11",{"name":69,"class":70},"Henry Ford Health System","OTHER",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":51,"sex":52,"minAge":17,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":22,"phases":80,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":94,"leadSponsor":96,"locationsCount":4},"100643655","does-trendelenburg-positioning-during-pulmonary-recruitment-breaths-affect-post-laparoscopy-shoulder-pain-100643655","NCT07631728","Does Trendelenburg Positioning During Pulmonary Recruitment Breaths Affect Post-laparoscopy Shoulder Pain","Trendelenburg Positioning During Pulmonary Recruitment Breaths: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Robot-assisted laparoscopic surgery for benign gynecologic indication\n* Surgery is booked for 60 minutes or longer\n* Reliable working phone number or email\n\nExclusion Criteria:\n\n* Patients with baseline opioid use\n* Patients with existing shoulder or neck pain\n* Active malignancy-related pain or surgery for malignant indication\n* Concomitant upper abdominal or thoracic surgery\n* Pre-existing emphysema, chronic obstructive pulmonary disease, or pneumothorax\n* Non-English speaking",{"count":79,"type":21},120,[24],"The goal of this clinical trial is to evaluate whether different positioning in the operating room during removal of laparoscopic surgical gas differs in post-surgery shoulder pain. An additional goal of this study is to evaluate whether positions change other post-surgery metrics such as bloating, time to passing gas, nausea and vomiting, and time to oral intake.\n\nResearchers will compare Trendelenburg positioning where your head is tilted down to supine (level or flat) positioning during removal of surgical gas.\n\nParticipants will be asked to complete brief surveys at 24 and 72-hours post-surgery.",[83,29,84],"Pain, Post-operative","Urogynecologic Surgery",[86,87,88,89,90],"Trendelenburg","pneumoperitoneum","post-laparoscopy shoulder pain","post-laparoscopy pain","gynecologic surgery",{"date":92,"type":35},"2026-06-08",{"date":37,"type":21},{"date":95,"type":21},"2027-11",{"name":97,"class":70},"Ankita Gupta",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":105,"targetDuration":107,"studyType":108,"phases":4,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":4},"100593367","study-of-the-relationship-between-curarization-and-pneumoperitoneum-in-laparoscopic-surgery-100593367","NCT07005518","Study of the Relationship Between Curarization and Pneumoperitoneum in Laparoscopic Surgery","PneumandTOF","Major patient, operated on by robot-assisted laparoscopic surgery, by two surgeons targeted for their similar working surgical technique.",{"count":106,"type":21},200,"3 Months","OBSERVATIONAL","The number of surgical procedures is increasing worldwide (1). Laparoscopic surgery is one of the surgical techniques that has become indispensable. Laparoscopic surgery is less invasive than laparotomy. Laparoscopic surgery is performed in several stages, one of which involves the creation of a peritoneal detachment. This detachment is achieved by the addition of a gas (CO2), which requires total relaxation of the abdominal muscle fibers. To achieve this, it is advisable to administer a muscle relaxant called curare (2). Curare-induced neuromuscular block, its depth and its release must be monitored during surgery. Curares act as acetylcholine antagonists, inducing neuromuscular block by competing with this neurotransmitter. In France, only one type of device, called an accelerometer, is used to monitor curarization. This device couples electrical stimulation of a nerve with an accelerometer. Curarization can be said to be deep, moderate, residual or absent. Despite curarization appearing deep to the accelerometer, operating conditions do not always seem ideal for abdominal contraction. Indeed, the muscles tested with this device do not concern the muscles involved in laparoscopic surgery.\n\nA currently unexploited surgical parameter, variation in insufflation pressure, could change our approach to intraoperative curarization.",[58,111,29],"Neuromuscular Blocking Agents",[113,114],"pneumoperitoneum pressure","curarization","2025-06-17",{"date":117,"type":35},"2025-06-18",{"date":119,"type":21},"2025-07-01",{"date":121,"type":21},"2027-11-01",{"name":123,"class":70},"Poitiers University Hospital",{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":51,"sex":16,"minAge":131,"maxAge":18,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":135,"conditions":136,"keywords":138,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":43},"100587491","role-of-individualized-peep-vs-fixed-peep-in-mechanical-ventilation-during-laparoscopic-surgeries-100587491","NCT06929078","Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic Surgeries","Role of Individualized Positive End-expiratory Pressure Versus Fixed Positive End-expiratory Pressure in Mechanical Ventilation During Laparoscopic Surgeries","Inclusion Criteria:\n\n* 1\\. Age Limit : 25 years to 65 years\n\n  2\\. Patients undergoing laparoscopic suregeries\n\n  3\\. ASA 1-3\n\nExclusion Criteria:\n\n* 1\\. Hemodynamic instability 2. Bronchospam 3. Patients having COPD 4. History of pulmonary bulla 5. Patients having history of pneumothora","25 Years",{"count":133,"type":21},75,[24],"To compare the effects of Individualized positive end-expiratory pressure with recruitment maneuver on respiratory parameters and oxygenation in mechanical ventilation during laparoscopic surgeries with the fixed positive end-expiratory pressure and conventional mechanical ventilation without positive end-expiratory pressure.",[58,29,137],"Positive End Expiratory Pressure (PEEP)",[139,140,141,142,143,144],"mechanical ventilation","lung compliance","positive end-expiratory pressure","respiratory mechanics","oxygenation index","driving pressure","2025-04-08",{"date":147,"type":35},"2025-04-16",{"date":149,"type":21},"2025-05",{"date":151,"type":21},"2025-11",{"name":153,"class":70},"Noor-Ul-Ain",{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":4,"eligibilityCriteria":160,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":161,"targetDuration":4,"studyType":108,"phases":4,"briefSummary":163,"conditions":164,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":43},"100568740","predictors-of-postoperative-complications-in-surgery-with-pneumoperitoneum-in-the-trendelenburg-position-100568740","NCT06685159","Predictors of Postoperative Complications in Surgery With Pneumoperitoneum in the Trendelenburg Position","Risk Factors for Postoperative Complications in Surgery With Pneumoperitoneum in Trendelenburg Position. Observational Pilot Study","Inclusion Criteria:\n\n* ASA Class I-IV.\n* Planned for laparoscopic surgery in the Trendelenburg position that is expected to last more than 2 hours.\n* Planned arterial catheter insertion.\n\nExclusion Criteria:\n\n* Pregnancy.\n* Planned open abdominal surgery.\n* Renal Replacement Therapy.",{"count":162,"type":21},100,"Evaluate early postoperative complications after surgery in Trendelenburg position with increased intraabdominal pressure (surgery with pneumoperitoneum). Evaluate the relationship between hemodynamic and metabolic changes on perioperative outcome.",[165,29],"Trendelenburg Position","2025-03-30",{"date":168,"type":35},"2025-04-01",{"date":170,"type":35},"2024-06-19",{"date":172,"type":21},"2026-06-19",{"name":174,"class":70},"Reuven Pizov",{"id":176,"slug":177,"hasResults":11,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":4,"eligibilityCriteria":181,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":182,"targetDuration":4,"studyType":22,"phases":183,"briefSummary":184,"conditions":185,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":189,"lastUpdatePostDateStruct":190,"startDateStruct":192,"completionDateStruct":194,"leadSponsor":196,"locationsCount":43},"100572730","low-pressure-pneumoperitoneum-using-airseal-for-reduction-in-postoperative-shoulder-pain-following-robot-assisted-hiatal-hernia-repair-100572730","NCT06737068","Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia Repair","Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia Repair: a Prospective Randomized Controlled Trial.","Inclusion Criteria:\n\n* patients undergoing elective robot assisted hiatal hernia repair\n\nExclusion Criteria:\n\n* patients less than 18 years of age\n* conversion to open surgery\n* BMI \\> 40\n* history of abdominoplasty\n* history of chronic pain and\u002For opioid dependence\n* history of COPD and\u002For supplemental oxygen use\n* pregnant patients\n* incarcerated patients\n* patient refusal",{"count":79,"type":21},[24],"The goal of this clinical trial is to evaluate the incidence and severity of post-operative shoulder pain following elective robot-assisted hiatal hernia repair in hopes of reducing pain and associated costs as well as clinic and emergency department visits due to this pain. You will undergo standard robot-assisted hiatal hernia repair with the standard postoperative care. The only difference is that you may be selected for the group where lower pressures used to fill your abdomen with carbon dioxide will be used, and you will be asked to fill out logs regarding your pain postoperatively. You will have postoperative appointments that are standard following this procedure.",[186,29,187,188],"Hernia, Hiatal","Postoperative Pain","Shoulder Pain","2024-12-11",{"date":191,"type":35},"2024-12-17",{"date":193,"type":21},"2025-01-01",{"date":195,"type":21},"2027-01",{"name":197,"class":70},"Riverside University Health System Medical Center",{"id":199,"slug":200,"hasResults":11,"nctId":201,"briefTitle":202,"officialTitle":202,"acronym":4,"eligibilityCriteria":203,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":204,"targetDuration":4,"studyType":22,"phases":206,"briefSummary":207,"conditions":208,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":211,"lastUpdatePostDateStruct":212,"startDateStruct":214,"completionDateStruct":216,"leadSponsor":218,"locationsCount":43},"100550474","comparison-between-low-pressure-pneumoperitoneum-with-high-pressure-pneumoperitoneum-in-post-operative-pain-shoulder-tip-pain-and-common-bile-duct-injuries-in-patients-undergoing-laparoscopic-cholecystectomy-100550474","NCT06447545","Comparison Between Low Pressure Pneumoperitoneum with High Pressure Pneumoperitoneum in Post-operative Pain, Shoulder Tip Pain and Common Bile Duct Injuries in Patients Undergoing Laparoscopic Cholecystectomy","Inclusion Criteria:\n\n* Patients from both genders\n* Patients undergoing laparoscopic cholecystectomy for cholelithiasis.\n\nExclusion Criteria:\n\n* Patients with cardiac abnormalities.\n* Patients with previous abdominal surgeries.",{"count":205,"type":21},82,[24],"This study aims to address the existing gap in knowledge by conducting a comprehensive comparison of the incidence of pain and common bile duct injuries in patients undergoing laparoscopic cholecystectomy using Low pressure pneumoperitoneum versus high pressure pneumoperitoneum.",[209,29,210],"Cholecystectomy","Pain, Postoperative","2024-12-02",{"date":213,"type":35},"2024-12-04",{"date":215,"type":35},"2024-05-19",{"date":217,"type":21},"2025-11-30",{"name":219,"class":70},"Gulab Devi Hospital",{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":226,"eligibilityCriteria":227,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":228,"targetDuration":4,"studyType":22,"phases":230,"briefSummary":231,"conditions":232,"keywords":235,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":248,"leadSponsor":250,"locationsCount":43},"100547845","ultrasonography-guided-pneumoperitoneum-for-laparoscopic-surgery-in-morbidly-obese-patients-100547845","NCT06413264","Ultrasonography Guided Pneumoperitoneum for Laparoscopic Surgery in Morbidly Obese Patients","Ultrasonography Guided Pneumoperitoneum for Laparoscopic Surgery in Morbidly Obese Patients: A Single-blinded Randomized Control Study (USP TRIAL)","USP","Inclusion Criteria:\n\n* All patients in the age group of 18 -65 years undergoing laparoscopic bariatric surgery with weight \\>100 kg\n* Subcutaneous fat thickness of more than 5 cm as determined by pre-operative ultrasonography\n* BMI \\> 40 kg\u002Fm2\n\nExclusion Criteria:\n\n* Patients who don't give consent and do not understand the nature of the study\n* Patients undergoing a re-do surgery",{"count":229,"type":21},40,[24],"Bariatric Surgery for morbid obesity is indicated when BMI \\> 40 kg\u002Fm2 without comorbidities or BMI \\> 35 kg\u002Fm2 with co-morbidities. Different surgeries performed for obesity are classified as restrictive, malabsorptive, and hybrid procedures.\n\nBecause laparoscopic surgery has increased the interest and growth of bariatric surgery, soaring demand for laparoscopic bariatric surgery from patients has boosted the boom in bariatric surgery worldwide.\n\nAchieving pneumoperitoneum is the initial and one of the most crucial steps in any laparoscopic surgery, giving the surgeon working space to operate on a particular organ\u002Forgan system. Usually, pneumoperitoneum is achieved either by a closed technique with a veress needle or an open technique with many variations like finger assisted or the conventional open technique.\n\nGiven the excess amount of subcutaneous fat in morbidly obese patients, putting a veress needle to achieve pneumoperitoneum successfully is particularly challenging which takes a toll on the operating surgeon when he\u002Fshe is trying to locate the midline one can either overshoot to cause omental emphysema or undershoot getting lost in the subcutaneous fat. It is usually done in the supra umbilical area. Sometimes, due to previous surgical scars other sites are preferred.\n\nSonography is routinely used by radiologists with negligible radiation exposure. Anesthesiologists in the operating room have used it for many assisted procedures like central line insertion \u002F giving nerve blocks. It can also be used in obese patients undergoing metabolic surgery to assist in creating pneumoperitoneum by a veress needle.\n\nAdvantages of Intraoperative ultrasonography in this particular study :\n\n1. To quantify the thickness of subcutaneous fat\n2. To visualise the linea alba and guide the veress needle safely into the peritoneal cavity\n3. Real-time visualisation of the pneumoperitoneum created\n4. Avoid complications like omental emphysema, bowel or vascular injury",[29,233,234],"Morbid Obesity","Bariatric Surgery Candidate",[87,236,237,238,239,240,241,242],"closed technique","Veress needle","ultrasonography-guided","morbidly obese","bariatric surgery","metabolic surgery","access-related injury","2024-07-29",{"date":245,"type":35},"2024-07-30",{"date":247,"type":35},"2024-07-01",{"date":249,"type":21},"2026-06-30",{"name":251,"class":70},"All India Institute of Medical Sciences, Bhubaneswar"]