[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"pocus\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:pocus":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,69,98],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100645011","ivc-window-agreement-study-100645011",false,"NCT07676968","IVC Window Agreement Study","Are Subcostal, Transhepatic, and Coronal Windows Interchangeable for IVC Ultrasonography? A Multicenter Prospective Agreement Study","Inclusion Criteria:\n\n* Adult patients (≥18 years) requiring ultrasonographic assessment of intravascular volume status will be consecutively enrolled.\n\nExclusion Criteria:\n\n* Pregnancy, refusal to participate, and inability to obtain any IVC image via the SC approach.","ALL","18 Years",{"count":19,"type":20},900,"ESTIMATED","OBSERVATIONAL","Ultrasonographic evaluation of the inferior vena cava (IVC) is widely used in emergency and critical care settings for noninvasive assessment of intravascular volume status. The subcostal (SC) window is the standard approach; however, it is frequently limited by obesity, bowel distension, or postoperative anatomical changes. In such cases, the right coronal (RC) and anterior transhepatic (aTH) windows have been proposed as alternatives.",[24,25,26,27],"Emergency Care","Volume Assessment","POCUS","Venous Hemodynamics",[29,30,31,26],"inferior vena cava","ultrasonography","volume status","NOT_YET_RECRUITING","2026-06-24",{"date":35,"type":36},"2026-06-30","ACTUAL",{"date":38,"type":20},"2026-08-01",{"date":40,"type":20},"2026-12-30",{"name":42,"class":43},"Gazi University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":68},"100593702","clinical-application-of-wearable-ultrasound-sensors-100593702","NCT07009873","Clinical Application of Wearable Ultrasound Sensors","Clinical Application on the R&D Purpose of Wearable Ultrasound Sensors:A Single-Center Prospective Study","Inclusion Criteria:\n\n* Age ≥ 18 yrs and able to consent\n* Relevant diagnosis for study arm (heart failure, lower-limb DVT, or ICU monitoring)\n* Adequate acoustic window and intact skin at sensor site\n\nArm-specific:\n\n* Heart-failure arm: Clinically stable HFrEF or HFpEF on standard therapy\n* DVT arm: Imaging-confirmed lower-limb DVT, anticoagulated or scheduled for intervention\n* ICU arm: ICU\u002Fpost-op patient requiring continuous bedside ultrasound\n\nExclusion Criteria:\n\n* Poor acoustic window preventing interpretable images\n* Local skin infection, open wound, or implant\u002Fhardware blocking sensor\n* Inability to cooperate with monitoring\n\nArm-specific:\n\n* Heart-failure arm: Acute MI or uncontrolled arrhythmia in past 3 months\n* DVT arm: Active bleeding or severe coagulopathy\n* ICU arm: Unstable multi-organ failure precluding safe monitoring",true,"70 Years",{"count":54,"type":20},300,"This study aims to develop and evaluate a wearable ultrasound imaging sensor for the early diagnosis and real-time monitoring of various diseases, such as cardiovascular conditions and structural abnormalities of superficial organs. With advancements in medical technology, wearable devices have attracted increasing attention for their portability and real-time capabilities.",[57,26],"DVT - Deep Vein Thrombosis","RECRUITING","2026-03-18",{"date":61,"type":36},"2026-03-20",{"date":63,"type":36},"2025-08-15",{"date":65,"type":20},"2026-09-30",{"name":67,"class":43},"Chinese PLA General Hospital",1,{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":75,"targetDuration":77,"studyType":21,"phases":4,"briefSummary":78,"conditions":79,"keywords":83,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":68},"100606662","concordance-and-discordance-in-the-assessment-of-volume-status-in-home-dialysis-patients-a-comparison-of-modified-medical-research-council-dyspnea-scale-physical-exam-and-point-of-care-ultrasound-pocus-100606662","NCT07178470","Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modified Medical Research Council Dyspnea Scale, Physical Exam, and Point of Care Ultrasound (POCUS)","Inclusion Criteria:\n\n1. Age: Greater than 18 years.\n2. Diagnosis: End-stage kidney disease (ESKD).\n3. Treatment: Receiving home dialysis, either peritoneal dialysis (PD) or home hemodialysis (HHD).\n4. Duration of Home Dialysis: At least three months on home dialysis.\n\nExclusion Criteria:\n\n1. Consent: Inability to provide informed consent.\n2. Inclusion Criteria: Not meeting any of the inclusion criteria.\n3. Pregnancy.\n4. Urgent-Start PD.\n5. Any other obvious cause of shortness of breath not related to volume overload including but not limited to pneumonia, pneumothorax, advanced COPD and Interstitial lung disease.",{"count":76,"type":20},90,"1 Day","Fluid overload, which is when your body has too much fluid, is one of the reasons why people on home dialysis need to go to the hospital. Fluid overload (when body has too much fluid) commonly presents as trouble breathing and leg swelling. Traditionally, doctors check for this by asking patients if they have any symptoms like leg swelling or shortness of breath and by doing a physical exam which includes listening to the lungs or looking for swelling in legs. However, a newer, safe, and non-invasive method called point-of-care ultrasound (POCUS) has become very popular. However, we don't have a lot of research yet on how POCUS and LUS (lung ultrasound) specifically help home dialysis patients, including those on peritoneal dialysis or home hemodialysis. Peritoneal dialysis is a way to clean your blood by putting a special fluid into your belly through a small tube. The fluid uses the natural lining of your belly as a filter to remove waste and extra water. Home hemodialysis is a treatment where a machine acts like an artificial kidney to clean your blood. You get trained to do this yourself at home by connecting to the machine with a couple of needles, which cleans your blood of waste and extra fluid. POCUS, especially a (LUS), has been shown to be useful for dialysis patients in outpatient units.\n\nThis study will compare different 3 different methods of detecting fluid overload: answering various survey questions, completing a physical exam, and a LUS. The study seeks to determine which of these methods is the best method to determine fluid overload.\n\nYou were selected as a possible participant because you are over 18 years old, diagnosed with End-stage kidney disease, and have been receiving home dialysis for at least three months.",[80,26,81,82],"Fluid Overload","Lung Ultrasound","Volume Status",[84,85,86,31,87,88],"pocus","fluid overload","lung ultrasound","modified Medical Research Council Dyspnea Scale","mMRC dyspnea scale","2026-02-24",{"date":91,"type":36},"2026-02-27",{"date":93,"type":36},"2026-01-09",{"date":95,"type":20},"2026-06",{"name":97,"class":43},"Indiana University",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":105,"targetDuration":4,"studyType":107,"phases":108,"briefSummary":110,"conditions":111,"keywords":116,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":4},"100619381","quantification-of-systemic-congestion-by-ultrasound-as-a-predictor-of-weaning-failure-from-mechanical-ventilation-100619381","NCT07343882","Quantification of Systemic Congestion by Ultrasound As a Predictor of Weaning Failure From Mechanical Ventilation","SCOUT","Inclusion Criteria:\n\n* Patients aged \\> 18 years.\n* Admitted to an Intensive Care Unit (ICU).\n* Requiring invasive mechanical ventilation for more than 48 hours.\n* Meeting the center's standard criteria to begin weaning and undergo an SBT.\n\nExclusion Criteria:\n\n* Inadequate ultrasound window for assessment.\n* Presence of \"do not reintubate\" orders.\n* Patients with a tracheostomy.\n* Presence of atrial fibrillation.\n* Diagnosed liver cirrhosis (portal hypertension).\n* Absence of qualified personnel to perform the ultrasound at the time of the SBT.\n* Denial of informed consent.",{"count":106,"type":20},350,"INTERVENTIONAL",[109],"NA","Mechanical ventilation is an essential, life-saving therapy in the ICU, allowing critically ill patients to rest and recover. Transitioning patients back to spontaneous breathing-known as weaning-is clinically challenging. The first attempt, the Spontaneous Breathing Trial (SBT), fails in 10-30% of cases. Identifying the mechanisms behind failure is crucial, as unsuccessful weaning prolongs ICU stay and increases the risk of reintubation, which worsens prognosis. The SCOUT study aims to improve prediction and management of weaning failure.\n\nThe main objective of the study is to evaluate whether a specific ultrasound-based method, the Venous Excess Ultrasound Score (VExUS), can predict failure of weaning from mechanical ventilation. A key pathophysiological factor is systemic venous congestion. When a patient initiates an SBT, the increased respiratory effort shifts venous return and may precipitate cardiovascular decompensation with pulmonary fluid accumulation, termed weaning-induced pulmonary edema (WIPO). Notably, this may occur even in patients without known cardiac disease.\n\nDetecting clinically relevant congestion before SBT is difficult. Fluid balance and body weight are imprecise, physical examination lacks sensitivity, and biomarkers such as NT-proBNP have limited predictive capacity. VExUS offers a promising, non-invasive approach by directly assessing venous flow patterns in major veins (inferior vena cava, hepatic, portal, and renal veins), providing an estimation of systemic venous pressure and congestion. The central hypothesis is that elevated VExUS grades prior to SBT will identify patients at high risk of failure, enabling proactive optimization and potentially improving outcomes.\n\nSCOUT is designed as a prospective, multicenter, observational study. Standard clinical management of mechanical ventilation and weaning remains unchanged. After informed consent, baseline data will be obtained immediately before SBT, including vital signs, ventilator parameters, blood sampling, and three non-invasive ultrasound assessments: cardiac, pulmonary, and VExUS. During the 30-120-minute SBT, the patient breathes with reduced ventilatory support while their clinical tolerance is evaluated. At the end of the SBT, selected measurements are repeated. Weaning failure is defined as: early termination of SBT due to intolerance, need for invasive or non-invasive ventilation within 48 h after extubation, or death within 48 h. Data are anonymized and stored securely (REDCap) in compliance with Spanish and EU data protection regulations.\n\nThe study is low-risk and provides no direct individual benefit, but may benefit future ICU patients by improving weaning strategies and prognostication.",[112,113,114,26,115],"Weaning Failure","Pulmonary Edema - Acute","Mechanical Ventilation","VExUS",[117,118],"Weaning induced pulmonary edema","Venous Excess Ultrasound grading system","2026-01-16",{"date":121,"type":36},"2026-01-21",{"date":123,"type":20},"2026-04-01",{"date":125,"type":20},"2027-06-01",{"name":127,"class":43},"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau"]