[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"polyps-colorectal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:polyps-colorectal":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100517289","testing-of-griptract-gi-endoscopic-tissue-manipulator-for-use-during-complex-endoscopic-polypectomies-in-the-colon-100517289",false,"NCT06015607","Testing of GripTract-GI Endoscopic Tissue Manipulator for Use During Complex Endoscopic Polypectomies in the Colon","Inclusion Criteria:\n\n* Patients scheduled for endoscopic removal of suspected adenomatous benign polyps(s)\n* Patients capable of giving informed consent English and lacking cognitive impairment\n* No medical contraindication to endoscopic mucosal resection or endoscopic submucosal dissection\n\nExclusion Criteria:\n\n* Patients less than 21 years of age\n* Any contraindication to colonoscopy with due to subject's colon anatomy (i.e., structure)\n* History of open or laparoscopic colorectal surgery\n* History of Inflammatory Bowel Disease\n* Patients requiring multiple polyp removals","ALL","21 Years",{"count":18,"type":19},30,"ESTIMATED","INTERVENTIONAL",[22],"NA","The goal of this clinical trial is to compare the safety and effectiveness of the GripTract GI Endoscopic Tissue Manipulator to the current standard of care for complex polypectomies in adults. The main questions it aims to answer are:\n\n1. How does the number and severity of Device-Attributable Adverse Events compare to the current standard of care?\n2. How is the procedure time affected?\n3. Is the ability to resect the tissue en bloc affected?\n4. What is the user feedback on the device performance?",[25],"Polyps Colorectal",[27],"endoscopic submucosal dissection","RECRUITING","2026-06-12",{"date":31,"type":32},"2026-06-15","ACTUAL",{"date":34,"type":32},"2026-06-11",{"date":36,"type":19},"2027-08",{"name":38,"class":39},"Actuated Medical, Inc.","INDUSTRY",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":15,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":56,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":70},"100407943","french-colorectal-esd-cohort-in-experts-centers-100407943","NCT04592003","French Colorectal ESD Cohort in Experts Centers","FECCo","Inclusion Criteria:\n\nAll patients addressed for a colorectal ESD\n\nExclusion Criteria:\n\nOpposition notified in the context of a non-opposition form after reading the information notice","18 Years",{"count":50,"type":19},1200,"OBSERVATIONAL","Initially developed in Japan for the treatment of endemic superficial gastric cancers, endoscopic submucosal dissection (ESD) allows resection of pre-neoplastic and neoplastic lesions of the digestive tract into a single fragment. It allows a perfect pathological analysis, and decreases the rate of recurrence of the adenoma to less than 2%. However, this procedure, which is technically more challenging, is also more risky (perforation rate at 4% vs. 1% for WF-EMR) and longer. Submucosal dissection is also more expensive in terms of equipment, but this difference can be offset by the cost of the high number of iterative colonoscopies required in patients who have had endoscopic resection by WF-EMR.\n\nScientific debate is agitating the Western world1,2 and Japanese experts do not perform WF-EMR anymore, whereas no comparative prospective study has compared these two procedures.\n\nA lot of centers in France performed colorectal ESD even for benign lesions and nationwide data about safety and efficiency is required to confirm the place of ESD for treatment of large superficial colorectal lesions.\n\nThe aim of this French multicenter cohort is to analyze the results of colorectal submucosal dissection on a large scale.",[54,25,55],"Cancer Colorectal","Endoscopic Submucosal Resection",[57,58,59],"Cancer colorectal","Polyps colorectal","Endoscopic submucosal resection","2025-09-08",{"date":62,"type":32},"2025-09-15",{"date":64,"type":32},"2020-01-01",{"date":66,"type":19},"2026-01-01",{"name":68,"class":69},"University Hospital, Limoges","OTHER",25,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":15,"minAge":48,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":20,"phases":82,"briefSummary":83,"conditions":84,"keywords":92,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":109},"100605106","optical-diagnosis-of-neoplasia-using-artificial-intelligence-100605106","NCT07158203","Optical Diagnosis of Neoplasia Using Artificial Intelligence","Assistance for Optical Diagnosis of Neoplasia Using Artificial Intelligence (FAIR Study)","FAIR","Endoscopists who meet the following inclusion\u002Fexclusion criteria Inclusion criteria\n\n* Endoscopists experienced with more than 100 colonoscopies. Exclusion criteria\n* Endoscopists who are involved in the development of the protocol of the present study.\n\nInclusion and exclusion criteria for the study videos. Inclusion criteria.\n\n* Videos with a duration of 15 seconds including both WL and NBI.\n* Videos with diminutive polyps with confirmed pathology. Exclusion criteria.\n* Videos with no clear image of the polyps.\n* Videos with more than one polyp on-screen.\n* Inflammatory bowel disease\n* Polyposis\n* Hereditary colorectal disease\n* Videos which CADx cannot provide sufficient number of outputs.",true,{"count":81,"type":19},70,[22],"Computer-aided diagnosis (CADx) for colonoscopy aims to enhance optical diagnosis but often underperforms when used alongside humans due to under-reliance on AI. Psychological interventions like cognitive forcing, such as delaying CADx suggestions, may improve human-AI interaction by fostering critical assessment. However, their impact on patient-important outcomes remains unexplored.\n\nThe investigators will conduct an ex-vivo randomized study with 70 endoscopists assessing 100 polyp videos (≤5 mm) using a CADx tool (GI Genius, Medtronic). Participants will be randomized to either:\n\n* Intervention group: CADx suggestions will be shown in the last 3 seconds of the 15 second polyp video.\n* Control group: CADx suggestions will be shown in real-time throughout the playback of the 15 second polyp video.\n\nThe primary endpoint is sensitivity for high-confidence neoplasia detection, with secondary endpoints assessing endoscopists' reliance on AI.\n\nCADx systems on the market function in various ways, such as real-time, delayed, or on-demand diagnosis. Our study aims to inform users and manufacturers whether cognitive forcing through delayed CADx suggestions enhances human-AI interaction, leading to improved clinical outcomes.",[25,85,86,87,88,89,90,91],"Colonoscopy","Optical Biopsy","Colorectal Cancer Control and Prevention","Colorectal Cancer Screening","Behavior Change","Psychological Factors","Psychological Intervention",[93,94,95,96,97,98],"behaviour","optical biopsy","colonoscopy","CADx system","colorectal polyps","psychological intervention","NOT_YET_RECRUITING","2025-08-28",{"date":102,"type":32},"2025-09-05",{"date":104,"type":19},"2025-09",{"date":106,"type":19},"2025-12",{"name":108,"class":69},"Fundacin Biomedica Galicia Sur",2]