[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"polyps-of-colon\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:polyps-of-colon":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100612324","effect-of-hfnc-on-incidence-of-hypoxia-during-sedated-gastrointestinal-endoscopy-in-critical-patients-100612324",false,"NCT07252102","Effect of HFNC on Incidence of Hypoxia During Sedated Gastrointestinal Endoscopy in Critical Patients","Effect of High Flow Nasal Cannula Oxygenation on Incidence of Hypoxia During Sedated Gastrointestinal Endoscopy in Critical Patients: A Multicentre Randomised Controlled Trial","Inclusion Criteria:\n\n1. 18≤ age ≤80, gender is not limited;\n2. Patients undergoing elective gastroenteroscopy or treatment;\n3. ASA grade Ⅲ\\~Ⅳ;\n4. 18 kg\u002Fm2≤BMI≤28kg\u002Fm2;\n5. The operation time of gastroenteroscopy is expected to be no more than 60min;\n6. Clearly understand, voluntarily participate in the study, and have informed consent from myself or my family members.\n\nExclusion Criteria:\n\n1. Patients with nasal congestion, nasal bleeding, recent nasal trauma, recent nasal surgery, increased intracranial pressure and skull fracture, etc., who can not perform high-flow nasal catheter oxygen;\n2. acute respiratory infections and asthma attacks;\n3. Patients diagnosed with COPD;\n4. Clear difficult airway;\n5. Acute upper gastrointestinal bleeding with shock;\n6. Gastrointestinal obstruction with gastric content retention;\n7. Allergic to sedatives such as propofol;\n8. Persons with no capacity for civil conduct such as cognitive dysfunction.","ALL","18 Years","80 Years",{"count":20,"type":21},450,"ESTIMATED","INTERVENTIONAL",[24],"NA","High flow nasal cannula oxygenation (HFNC) offers high flow and concentration oxygen delivery, providing excellent non-respiratory oxygenation. As a relatively new oxygen delivery method, it has gained widespread use. We have demonstrated that high flow nasal cannula oxygenation reduce the incidence of hypoxia during sedated gastrointestinal endoscopy in patients with American Anesthesiologist Rating (ASA rating) grades 1 to 2 and obesity. We hypothesized that HFNC could mitigate the risk of hypoxia in critical patients during sedated gastrointestinal endoscopy. To confirm this, we selected critical patients with ASA grades 3 to 4 who were scheduled for gastrointestinal endoscopy. We observed and compared the incidence of hypoxia (75%≤SpO2 \\\u003C 90% and \\\u003C 60S), severe hypoxia (SpO2\\\u003C75% for any duration or 75%≤SpO2 \\\u003C 90%, ≥60s), subclinical respiratory depression (90%≤SpO2 \\\u003C 95%), respiratory-related adverse events, sedation-related adverse events, and complications associated with high flow nasal cannula oxygenation using HFNC or regular nasal cannula during the sedated gastrointestinal endoscopy.",[27,28,29],"Liver Cirrhosis","Polyps of Colon","Gastrointestinal Dysfunction",[31,32,33,34],"critical patients","HFNC","High flow nasal cannulas oxyge","hypoxia","RECRUITING","2026-01-16",{"date":38,"type":39},"2026-01-20","ACTUAL",{"date":41,"type":39},"2025-11-20",{"date":43,"type":21},"2026-12-30",{"name":45,"class":46},"Zhejiang University","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":63,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100444184","early-diagnosis-real-time-healthcare-system-for-cancer-trial-100444184","NCT05064124","Early DiAgnosis Real-Time Healthcare System for CANcer Trial","EARTHSCAN","Inclusion Criteria:\n\n* Participants scheduled to undergo a screening, surveillance or symptomatic colonoscopy with an endoscopist participating in the study phase of the trial.\n* Male and female participants aged 18 years or older at the time of informed consent.\n* Participants able to comprehend, sign and date the written informed consent document to participate in the study.\n\nExclusion Criteria:\n\n* Emergency and\u002For inpatient colonoscopies\n* Participants with inflammatory bowel disease (IBD)\n* Participants with current Colorectal Cancer (CRC)\n* Participants with a contraindication for biopsy or polypectomy. These include:\n\n  * Participants who have not withheld medications pre-disposing to bleeding at time of colonoscopy as per local site \u002Fnational guidelines.\n  * Participants with a history of haemostasis disorders (haemostasis disorders will include but will not be limited to: participants with haemophilia or other congenitally acquired clotting factor deficiencies, participants with cirrhosis with coagulopathy, participants known to have thrombocytopenia (\\\u003C80,000 platelet\u002Ful) and individuals with Von Willebrand's disease or other known platelet malfunction disorders)\n* Participant is enrolled in another research study with an investigational medicinal product (IMP) or non-IMP that pre-disposes them to bleeding",{"count":55,"type":21},420,"OBSERVATIONAL","The purpose of the study is to assess whether the AI characterisation system of the CADDIE device improves the endoscopists accuracy in the optical diagnosis of diminutive colorectal polyps in the bowel during colonoscopy. Participants will either have a colonoscopy with the assistance of the CADDIE device characterisation AI system (\"intervention group\") or have a colonoscopy in line with routine clinical practice i.e., without the CADDIE device characterisation AI system (\"control group\"). The randomisation method of this trial will allocate enrolled participants to the \"intervention\" group and to the \"control\" group by a technique similar to flipping a coin.",[59,60,61,62,28],"Polyps","Adenoma Colon","Colorectal Polyp","Colon Polyp",[64,65,66],"Artificial intelligence","Endoscopy","ADR","2024-12-10",{"date":69,"type":39},"2024-12-16",{"date":71,"type":39},"2024-07-18",{"date":73,"type":21},"2025-05",{"name":75,"class":46},"University College, London",1,{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":76},"100566698","efficacy-and-safety-research-of-cold-snare-polypectomy-and-hot-snare-polypectomy-in-the-treatment-of-4-9-mm-diameter-colorectal-0-isp-and-0-ip-polyps-a-prospective-multicenter-randomized-controlled-studyfast--rest-study-100566698","NCT06658561","Efficacy and Safety Research of Cold Snare Polypectomy and Hot Snare Polypectomy in the Treatment of 4-9 mm Diameter Colorectal 0-Isp and 0-Ip Polyps: a Prospective, Multicenter, Randomized Controlled Study(FAST -REST Study)","Inclusion Criteria:\n\n1. Age: 18-80 years old, male or female\n2. At least one polyp with size of 4-9 mm 0-Isp or 0-Ip is found during colonoscopy\n3. Voluntarily sign informed consent for endoscopic treatment\n\nExclusion Criteria:\n\n1. Boston Bowel Preparation Scale\\\u003C6 points.\n2. Patients who receive antiplatelet\u002Fanticoagulant therapy within 5 days before polypectomy.\n3. Participants with a contraindication to colonoscopy and polypectomy.\n4. Patients with inflammatory bowel disease or gastrointestinal polyposis.\n5. Lesions with submucosal invasion and those suspected of being cancerous at the preprocedural diagnostic evaluation.\n6. Patients with pregnancy.",{"count":84,"type":21},982,[24],"This study will evaluate the efficacy and safety of cold snare polypectomy(CSP) and hot snare polypectomy(HSP) in the treatment of colorectal 4-9mm 0-Isp and 0-Ip polyps, and compare the complete resection rate, postoperative late bleeding rate, intraoperative bleeding rate, en bloc resection rate, operation time and the number of metal clips used. The conclusion of this study will help clinical doctor develop more effective resection strategies for colorectal 0-Isp and 0-Ip polyps, and provide more effective treatment for patients.",[88,89,28],"Cold Snare Resection","Hot Snare Resection",[91,92,93],"cold snare resection","hot snare resection","colorectal Polyps","NOT_YET_RECRUITING","2024-10-24",{"date":97,"type":39},"2024-10-26",{"date":99,"type":21},"2024-10-15",{"date":101,"type":21},"2026-03-01",{"name":103,"class":46},"Ruijin Hospital"]