[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"poor-responders-in-ivf\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:poor-responders-in-ivf":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100328775","efficacy-of-metoclopramide-in-poor-ovarian-response-ivf-patients-100328775",false,"NCT03560583","Efficacy of Metoclopramide in Poor Ovarian Response IVF Patients","Efficacy of Metoclopramide in Poor Ovarian Response IVF Patients: a Randomised, Double-blind, Placebo-controlled Trial","Inclusion Criteria:\n\n* Poor response according to \"Bologna criteria\"\n\nExclusion Criteria:\n\n* Allergy to metoclopramide\n* Prolactinemia\n* Women treated with dopamine agonists",true,"FEMALE","18 Years","54 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","Poor ovarian response population of ART are considered the biggest challenge for providers. Hitherto, no one protocol has been proven to be effect in this subgroup of IVF patients.\n\nMetoclopramide belongs to the antiemetic group, used for motion sickness and during early gestation for hyperemesis gravidarum.\n\nThe mechanism of action is antagonisim to dopamine receptors. We hypothesize than by blocking dopamine receptors and decreasing the dopaminergic tone there is a possibility to increase the sensitivity of ovarian response to gonadotropins during controlled ovarian stimulation and result in increased oocyte retrival.",[28],"Poor Responders in IVF","RECRUITING","2025-02-06",{"date":32,"type":33},"2025-02-10","ACTUAL",{"date":35,"type":33},"2021-05-05",{"date":37,"type":22},"2028-07",{"name":39,"class":40},"Barzilai Medical Center","OTHER"]