[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"positive-c-acnes-culture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:positive-c-acnes-culture":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100579986","post-incision-antimicrobial-wash-vs-c-acnes-in-shoulder-arthroplasty-100579986",false,"NCT06831422","Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty","Application of a Novel Antimicrobial Wash Versus Hydrogen Peroxide Versus Povidone-iodine to the Dermis and Incidence of Cutibacterium Acnes During Shoulder Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Indicated and scheduled for primary shoulder arthroplasty.\n* Chronic severe glenohumeral osteoarthritis, avascular necrosis, post traumatic osteoarthritis, rotator cuff arthropathy,\n* Ability to read and understand English\n* Age ≥18 years\n* Patient failed ≥6 weeks of conservative treatment, which included non-steroidal anti-inflammatory drugs (NSAIDS)\n\nExclusion Criteria:\n\n* Patient with history of prior native shoulder septic arthritis or infection\n* Prior surgery of affected shoulder\n* Proximal Humerus Fracture\n* Active infection\n* Cancer\n* Autoimmune and rheumatologic disorders, including rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus\n* History of allergic reaction to citric acid-derived products","ALL","18 Years",{"count":19,"type":20},150,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this randomized controlled trial is to determine the effect of post-incision wash using various novel antimicrobial solutions on the rate of positive C. Acnes cultures collected from adults undergoing primary shoulder replacement surgery. Subjects will be randomly assigned in a 1:1:1:1 fashion to groups that will receive one of the following treatments:\n\n* Post-incision application of Xperience Antimicrobial wash (NextScience, Jacksonville, FL)\n* Post-incision application of 3% hydrogen peroxide\n* Post-incision application of 10% povidone-iodine (betadine)\n* No post-incision treatment (control)\n\nThe investigators hypothesize that the subjects treated with the antimicrobial solutions after initial incision will have lower rates of positive C. Acnes cultures. The investigators also hypothesize that post-incision application of Xperience Antimicrobial wash and Betadine will have an equal reduction in the incidence of C. acnes as Hydrogen Peroxide.",[26,27],"Shoulder Arthroplasty","Positive C. Acnes Culture",[26,29,30,31],"Antimicrobial","Post-incision wash","C. Acnes","RECRUITING","2025-05-30",{"date":35,"type":36},"2025-06-04","ACTUAL",{"date":38,"type":36},"2025-05-05",{"date":40,"type":20},"2027-09",{"name":42,"class":43},"Henry Ford Health System","OTHER"]