[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"positive-pressure-respiration\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:positive-pressure-respiration":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":4},"100642479","ventilation-modalities-during-transport-of-postoperative-critically-ill-patients-to-the-icu-100642479",false,"NCT07646249","VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU","VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU - A Multicenter Observational Study","VENTICRIT","Inclusion criteria\n\n* Intubated patients undergoing general anesthesia for non-cardiac surgery\n* Requirement for postoperative IMV\n* Age ≥18 years\n* Obtained informed consent Exclusion criteria\n* Patients undergoing cardiac surgery\n* Patients receiving preoperative mechanical ventilation prior to surgery.","ALL","18 Years",{"count":20,"type":21},800,"ESTIMATED","OBSERVATIONAL","Patients undergoing major non-cardiac surgery may require postoperative mechanical ventilation and transfer from the operating room to the intensive care unit (ICU). This intra-hospital transport phase is critical, as patients may experience changes in respiratory and hemodynamic status, including alterations in oxygenation, ventilation, blood pressure, and heart rate.\n\nDuring transport, ventilatory support may be provided using different strategies, including manual ventilation with a bag-valve device or mechanical ventilation with a portable ventilator. Although both approaches are commonly used in clinical practice, there is limited evidence comparing their effects on respiratory function, gas exchange, and overall physiological stability during and after transport.\n\nThis multicenter, prospective observational study aims to describe current clinical practices in ventilatory support during intra-hospital transport in adult patients undergoing non-cardiac surgery who require ICU admission. The study will also evaluate changes in vital signs, arterial blood gas parameters, and respiratory mechanics, as well as the occurrence of adverse events during transport and postoperative pulmonary complications within the first five days after surgery.\n\nNo additional interventions or procedures beyond standard clinical care will be performed. All data will be collected as part of routine clinical practice. The results of this study are expected to improve the understanding of ventilation management during transport and to identify safer and more effective strategies for critically ill postoperative patients.",[25,26,27,28,29,30],"Respiration, Artificial","Positive-Pressure Respiration","Postoperative Complications (Cardiopulmonary)","Postoperative Complications","Critical Illness","Intensive Care Units",[32,33,34,25,26,35,28,36,29,30,37,38,39],"Intra-hospital Transport","Mechanical Ventilation","Manual Ventilation","Postoperative Care","Postoperative Pulmonary Complications","Endotracheal Intubation","General Anesthesia","Non-Cardiac Surgery","NOT_YET_RECRUITING","2026-06-09",{"date":43,"type":44},"2026-06-12","ACTUAL",{"date":46,"type":21},"2026-07-01",{"date":48,"type":21},"2027-10-01",{"name":50,"class":51},"Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva","OTHER",{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100549172","personalized-ventilation-based-on-ventilation-perfusion-mismatch-and-lung-recruitability-100549172","NCT06430554","Personalized Ventilation Based on Ventilation-perfusion Mismatch and Lung Recruitability","Personalized Ventilatory Strategy Based on Ventilation-perfusion Mismatch and Lung Recruitability in Moderate-to-severe ARDS Patients","Inclusion Criteria:\n\n1. age ≥18 years\n2. Moderate-to-severe ARDS as per the 2023 ESICM definition\n3. Undergoing invasive mechanical ventilation\n4. Planned prone position based on the attending physicians' decisions\n5. Signed informed consent\n\nExclusion Criteria:\n\n1. age ≥85 years\n2. Pregnancy\n3. Severe hemodynamic instability (\\> 30% increase in vasopressors in the last 6 hours or norepinephrine \\> 0.5 µg\u002Fkg\u002Fmin)\n4. Clinically suspected elevated intracranial pressure (\\>18 mm Hg)\n5. Bronchopleural fistula\n6. Contraindication to EIT monitoring (e.g. burns, pacemaker, thoracic wounds limiting electrode belt placement)\n7. Severe hypernatremia (\\>170mmol\u002FL)\n8. Re-admission of patients already enrolled in this study, or patients who are participating in other studies","85 Years",{"count":61,"type":21},40,"This observational study will explore the effects of PEEP and position on regional lung ventilation-perfusion mismatch by electrical impedance tomography (EIT) in moderate-to-severe ARDS patients with different lung recruitability.",[64,26,33],"Respiratory Distress Syndrome",[66],"Acute respiratory distress syndrome;Positive end expiratory pressure; Prone Position; Ventilation\u002Fperfusion matching.","RECRUITING","2026-01-29",{"date":70,"type":44},"2026-02-03",{"date":72,"type":44},"2024-06-08",{"date":74,"type":21},"2026-06-30",{"name":76,"class":51},"Zhongda Hospital",1]