[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-bariatric-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-bariatric-surgery":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,53,86],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100625526","concurrent-exercise-effects-in-post-bariatric-patients-100625526",false,"NCT07423780","Concurrent Exercise Effects in Post-Bariatric Patients","Effect of a Concurrent Exercise Program on Muscle Quality, Body Composition, Functional Response, and Quality of Life in Individuals Undergoing Bariatric Surgery","BAR-EX","Inclusion Criteria\n\n* Voluntarily agree to participate and sign informed consent.\n* Men and women aged 18 to 60 years.\n* Have undergone bariatric surgery (sleeve gastrectomy or gastric bypass) at BUPA Clinic Santiago.\n* Have a medical indication for metabolic rehabilitation.\n* May present associated comorbidities such as insulin resistance syndrome, dyslipidemia, arterial hypertension, and\u002For hypothyroidism.\n\nExclusion Criteria\n\n* Diagnosis of type 1 or type 2 diabetes mellitus.\n* Severe musculoskeletal disorders that impair ambulation or limit participation in the exercise program.\n* History of a cardiovascular event.\n* Severe cardiorespiratory diseases that significantly reduce physical capacity or cause dyspnea at rest or with minimal exertion.\n* Dependence on supplemental oxygen.\n* Bariatric surgery-related complications, including:\n* Staple line leak or fistula\n* Hemorrhage\u002Fbleeding\n* Stenosis or gastric narrowing\u002Fstricture\n* Intra-abdominal abscess\n* Hypersensitivity (as clinically determined).\n* Hepatic and\u002For renal insufficiency.","ALL","18 Years","60 Years",{"count":21,"type":22},84,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to evaluate the effect of a 5-week concurrent exercise program (aerobic and resistance training) on muscle quality, body composition, functional response, and quality of life in individuals undergoing bariatric surgery.\n\nThis is a single-center, prospective, longitudinal, non-randomized controlled clinical trial with two groups: intervention and control. A total of 84 adults aged 18 to 60 years who have undergone sleeve gastrectomy or gastric bypass and have a medical indication for metabolic rehabilitation will be recruited.\n\nThe intervention group will complete a supervised concurrent exercise program for 5 weeks, consisting of two in-person sessions per week (10 sessions in total), while the control group will continue with usual care without participating in a structured exercise program. All participants will be assessed at two time points: baseline (postoperative week 4) and 7 weeks after baseline (after 5 weeks of intervention and 1 week of rest).\n\nThe primary outcome will be muscle quality of the rectus femoris assessed by ultrasound (echo intensity). Secondary outcomes will include body composition (bioelectrical impedance analysis), functional performance (one-minute sit-to-stand test), and quality of life (Moorehead-Ardelt II questionnaire).\n\nAdditionally, adherence to the exercise program in the intervention group will be evaluated as the percentage of attendance to supervised sessions, and its association with the magnitude of changes in outcomes will be analyzed under a dose-response framework.\n\nThe results are expected to provide clinically relevant evidence on the effectiveness of exercise in the early postoperative period and to support the optimization of metabolic rehabilitation strategies after bariatric surgery.",[28,29],"Obesity & Overweight","Post-bariatric Surgery",[31,32,33,34,35,36,37,38,39],"Muscle quality","Body composition","Functional capacity","Therapeutic exercise","Quality of life","concurrent exercise","one-minute sit-to-stand","ectus femoris ultrasound","bioelectrical impedance analysis","RECRUITING","2026-04-28",{"date":43,"type":44},"2026-05-04","ACTUAL",{"date":46,"type":44},"2025-08-11",{"date":48,"type":22},"2028-12-31",{"name":50,"class":51},"Universidad Autónoma de Chile","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":23,"phases":63,"briefSummary":65,"conditions":66,"keywords":71,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":85},"100272246","early-phase-1-the-effects-of-bariatric-surgeries-on-glucose-metabolism-100272246","NCT02823665","The Effects of Bariatric Surgeries on Glucose Metabolism","Inclusion Criteria:\n\n* Hypoglycemic RYGB patients with documented blood glucose level \\\u003C50 mg\u002Fdl\n* Asymptomatic individuals with bariatric surgery\n* Healthy non-surgical patients with no personal history of diabetes\n* Subjects must physically be able to come to our clinical research center Cedars-Sinai Medical Center\n\nExclusion Criteria:\n\n* Active heart, lung, liver, gastrointestinal or kidney disease; unable to give informed consent; pregnancy; uncontrolled high blood pressure or high cholesterol; significant anemia (hemoglobin \\\u003C11g\u002FdL); prisoners or institutionalized individuals; type 2 diabetes mellitis; development of any serious medical or psychiatric illness during recruitment or studies;\n* RYGB patients will be disqualified if they have gastric outlet obstruction or severe diarrhea.\n* Healthy non-surgical patients with personal history of diabetes\n\nFor administration of atropine, the following exclusions also apply:\n\n* History of glaucoma\n* Uncontrolled hypertension (any subjects with BP\\>140\u002F90 and history of dyslipidemia\n* Taking any medication that might interact with atropine and cannot be stopped will be excluded from the study)\n* Myasthenia gravis\n* Brain pathology\n* Enlarged prostate in men",true,"65 Years",{"count":62,"type":22},200,[64],"EARLY_PHASE1","The purpose of this study is learn the effect of gastric bypass surgery and sleeve gastrectomy on glucose metabolism mediated by neural and hormonal factors initiated after eating.",[67,68,69,70],"Post Bariatric Surgery","Gastric Bypass","Sleeve Gastrectomy","Hypoglycemia After Gastric Bypass",[72,73,74,75],"gastric bypass surgery","Hypoglycemia","sleeve gastrectomy","glucose tolerance","2025-09-08",{"date":78,"type":44},"2025-09-09",{"date":80,"type":4},"2015-07",{"date":82,"type":22},"2027-08",{"name":84,"class":51},"The University of Texas Health Science Center at San Antonio",2,{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":60,"enrollmentInfo":94,"targetDuration":4,"studyType":23,"phases":96,"briefSummary":97,"conditions":98,"keywords":99,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":103,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":107,"locationsCount":85},"100194164","early-phase-1-glucagon-like-peptide-1-glucose-metabolism-and-gastric-bypass-100194164","NCT01803451","Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass","The Role of Glucagon Like Peptide-1 in Glucose Metabolism and Weight Loss Following Gastric Bypass Surgery","GLP-1","Inclusion Criteria:\n\n* age 18-65\n* healthy control without diabetes or active organ disease\n* Individuals with bariatric surgery\n* recurrent hypoglycemia post gastric bypass\n\nExclusion Criteria:\n\n* pregnancy\n* significant anemia\n* diabetes currently unless pre-op for bariatric surgery procedure\n* GI obstruction",{"count":95,"type":22},80,[64],"The overall goal of this project is to understand the mechanisms by which gastric bypass surgery improves glucose metabolism.\n\nThe central hypothesis guiding this project is that the reconfiguration of intestinal transit with the Roux-en-Y will increase the release of insulinotropic GI hormones, termed incretins that improve insulin secretion and glucose metabolism. The study is divided into three specific aims.\n\n1. To determine the role of incretin hormones on insulin secretion in patients with gastric bypass surgery using intravenous-oral hyperglycemic clamp.\n2. To compare incretin effect and glucose tolerance among patient who suffer from hypoglycemia after RYGB and asymptomatic surgical and non-surgical individuals.\n3. To quantify the contribution of GLP-1 to incretin effect enhancement following surgery.",[29],[100,101,102],"gastric bypass","glucose metabolism","hypoglycemia",{"date":78,"type":44},{"date":105,"type":4},"2005-11",{"date":82,"type":22},{"name":84,"class":51}]