[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-extraction-alveolar-bone-resorption\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-extraction-alveolar-bone-resorption":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100611571","comparison-of-demineralized-and-mineralized-dentin-grafts-in-ridge-preservation-100611571",false,"NCT07242313","Comparison of Demineralized and Mineralized Dentin Grafts in Ridge Preservation","Comparative Study Between Demineralized and Mineralized Allogeneic Dentin Grafts for Alveolar Ridge Preservation: A Randomized Controlled Clinical Trial","DDG-ARP","Inclusion Criteria:\n\nAdults aged 18 to 60 years.\n\nMedically healthy patients classified as ASA I.\n\nPresence of a single non-restorable tooth indicated for extraction in the posterior maxilla.\n\nAdequate oral hygiene, with plaque and bleeding indices both below 20%.\n\nSufficient bone volume to allow socket preservation without requiring simultaneous augmentation.\n\nPatients willing to participate in the study and able to provide written informed consent.\n\nAbility to commit to follow-up visits for up to 6 months.\n\nExclusion Criteria:\n\nSmokers or tobacco users of any form.\n\nPresence of uncontrolled systemic diseases (e.g., uncontrolled diabetes).\n\nConditions affecting bone metabolism (e.g., osteoporosis, long-term corticosteroid therapy).\n\nPregnant or lactating women.\n\nHistory of radiotherapy in the head and neck region.\n\nActive infection or suppuration at the extraction site.\n\nImmunocompromised patients or those on immunosuppressive therapy.\n\nPatients taking medications known to impair healing (e.g., bisphosphonates).\n\nAllergy or hypersensitivity to any study-related materials.","ALL","18 Years","60 Years",{"count":21,"type":22},45,"ESTIMATED","INTERVENTIONAL",[25],"NA","This clinical investigation aims to assess how two different allogeneic dentin graft materials - one de-mineralized and the other mineralized - influence bone preservation following extraction of a single upper posterior tooth. A total of 45 patients will be randomly allocated into three equal groups: a socket-only spontaneous healing group (control), a de-mineralized dentin graft group, and a mineralized dentin graft group. Over a six-month period after extraction, measurements will be taken using CBCT to monitor changes in ridge width, height, and bone density. Secondary outcomes include patient-reported pain, postoperative swelling, satisfaction levels, width of keratinized tissue, and histomorphometric data from biopsy samples at implant placement. Findings from this trial may support evidence-based decisions in alveolar ridge preservation and help clinicians choose the most predictable grafting strategy before implant placement.",[28,29],"Alveolar Ridge Preservation","Post Extraction Alveolar Bone Resorption",[28,31,32,33,34,35,36,37,38],"Socket Preservation","Post-Extraction Bone Loss","Dentin Graft","Allogeneic Dentin","Demineralized Dentin Matrix","Mineralized Dentin Graft","Bone Regeneration","Histomorphometry","RECRUITING","2025-11-21",{"date":42,"type":43},"2025-11-24","ACTUAL",{"date":45,"type":43},"2025-10-21",{"date":47,"type":22},"2026-08-31",{"name":49,"class":50},"Kafrelsheikh University","OTHER"]