[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-operative-atrial-fibrillation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-operative-atrial-fibrillation":88},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,45,75,102,128],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100592157","boxx-noaf-clinical-trial-100592157",false,"NCT06989775","BoxX-NoAF Clinical Trial","EnCompass Clamp and the AtriClip in Box Lesion and Left Atrial Appendage EXclusion Procedure for the Prevention of New Onset of Atrial Fibrillation","Inclusion Criteria:\n\n* Planned and clinically indicated for cardiac surgical procedure requiring cardiac bypass and opening of the pericardium\n* Age ≥ 65 years and CHA2DS2-VASc ≥ 3\n\nExclusion Criteria:\n\n* Documented history of atrial fibrillation or atrial flutter anytime prior to the cardiac surgery\n* Prior procedure involving opening the pericardium or entering the pericardial space\n* Patients undergoing off-pump surgery\n* Prior LAA occlusion, exclusion, or removal (surgical or percutaneous)\n* Presence of a permanent pacemaker\n* Infiltrative cardiomyopathies (i.e. amyloidosis)\n* Planned cardiac surgical procedure using non-sternotomy approaches\n* Patients whose planned procedure is a heart transplant or implantation of any long-term ventricular assist devices\n* Presence of ventricular arrhythmia\n* Active endocarditis\n* NYHA Class IV heart failure symptoms\n* Preoperative need for an intra-aortic ballon pump or intravenous inotropes\n* Active systemic infection at the time of cardiac surgery requiring antibiotics\n* Known allergy to Nitinol or nickel sensitivity\n* Known medical condition with expected survival of less than 1 year\n* Other comorbidities that in the Investigator's opinion make the subject unsuitable candidate to complete the protocol required intervention or visits\n* Current enrollment in an investigation or trial or an investigational devices or investigational drug that would interfere with this trial\n* Mental impairment or other psychiatric conditions which may not allow the patient to understand the nature, significance, and scope of the trial.\n* Pregnancy\n* Known severe symptomatic carotid disease",true,"ALL","65 Years",{"count":20,"type":21},960,"ESTIMATED","INTERVENTIONAL",[24],"NA","Post Operative Atrial Fibrillation (POAF) is the most common complication of cardiac surgery. POAF incidence can exceed 50% depending on the patient baseline characteristics and surgery type. Patients with POAF tend to have worse acute and long-term clinical outcomes. BoxX-NoAF is a randomized trial to evaluate if prophylactic ablation and exclusion of the Left Atrial Appendage at the time of other routine cardiac surgery can reduce the incidence of post operative AF and clinical AF during long term follow up in patients who have not yet developed AF but are at risk.",[27,28],"Post Operative Atrial Fibrillation","Atrial Fibrillation, Postoperative",[30,31],"Post operative AF","Clinical AF","RECRUITING","2026-06-26",{"date":35,"type":36},"2026-06-29","ACTUAL",{"date":38,"type":36},"2025-10-24",{"date":40,"type":21},"2029-12",{"name":42,"class":43},"AtriCure, Inc.","INDUSTRY",27,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":74},"100615034","phase-4-colchicines-effect-on-inflammatory-markers-100615034","NCT07287345","Colchicine's Effect on Inflammatory Markers","Adjunctive Colchicine's Effect on Inflammatory Markers and Corresponding New-Onset Atrial Fibrillation Rates Post Coronary Artery Bypass Graft Procedure: A Pilot Study","Inclusion Criteria:\n\n* Age 18 years and older\n* Coronary artery bypass graft (CABG) planned procedure\n\nExclusion Criteria:\n\n* History of atrial fibrillation\n* Off-pump CABG procedure\n* Current treatment with colchicine for any cause\n* Hypersensitivity to colchicine (as indicated by rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever)\n* Emergency cardiac surgery\n* Extracorporeal Membrane Oxygenation (ECMO) pre- or post-cardiac surgery\n* Heart transplant patients\n* Left ventricular assist device (LVAD) patients\n* Serum creatinine \\>2.0 mg\u002FdL\n* Preoperative elevated CK or known myopathy\n* Severe liver disease or elevation of serum transaminases (\\>1.5 times the upper limit of 40 units\u002Fliter)\n* Chronic intestinal disease or blood dyscrasia\n* Unable to speak English\n* Pregnancy or lactation in women","18 Years","99 Years",{"count":55,"type":21},24,[57],"PHASE4","This study wants to see if the medicine colchicine can help lower inflammation and reduce the chance of developing an irregular heartbeat (atrial fibrillation) after heart bypass surgery. Adults having coronary artery bypass surgery (CABG) can join. Participants will be randomly placed into one of two groups: one group will receive colchicine along with usual care, and the other will receive a placebo (a look-alike capsule with no medicine) along with usual care. Everyone will take a study capsule, and neither the patients nor the study team will know which capsule is being given. Everyone in the study will take study capsule, and neither the patients nor the study team will know who is receiving colchicine or placebo. Blood samples and health information will be collected before surgery; at 24, 48, 72, and 96 hours after surgery; and again at 10 days after surgery or at hospital discharge, whichever comes first. The investigators will look at inflammation marker levels, whether atrial fibrillation happens, and any side effects. This small study will help to generate effect size estimates and safety data that will help plan a larger study in the future.",[60,61,27,62,63],"Colchicine","Inflammation in Cardiac Surgery","Inflammatory Markers","Colchicine Adverse Reaction","2026-06-23",{"date":66,"type":36},"2026-06-25",{"date":68,"type":36},"2026-01-16",{"date":70,"type":21},"2026-12-30",{"name":72,"class":73},"Ayesha Ather","OTHER",1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":74},"100589716","postoperative-atrial-fibrillation-in-cardiac-surgery-100589716","NCT06958029","Postoperative Atrial Fibrillation in Cardiac Surgery","Incidence and Risk Factors of Postoperative Atrial Fibrillation in Cardiac Surgery Patients","POAF","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patients undergoing cardiac valve surgery or coronary artery bypass grafting (CABG) procedures\n\nExclusion Criteria:\n\n* Patients undergoing aortic surgery\n* Patients undergoing MAZE procedure\n* Incomplete medical records\n* Patients who required mechanical circulatory support before surgery\n* Patients who died during surgery or within 3 days after surgery",{"count":84,"type":21},275,"OBSERVATIONAL","This multicenter observational study aims to investigate the incidence and identify risk factors associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac surgery at three medical centers in Thailand. The study will examine patient characteristics, surgical factors, and anesthetic management practices that may contribute to the development of this common postoperative complication.",[88],"Post-operative Atrial Fibrillation",[90,91,92],"postoperative","atrial fibrillation","cardiac surgery","2025-04-27",{"date":95,"type":36},"2025-05-06",{"date":97,"type":36},"2025-04-01",{"date":99,"type":21},"2025-06-10",{"name":101,"class":73},"Khon Kaen University",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":112,"conditions":113,"keywords":116,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":74},"100575149","association-between-galectin-3-and-post-operative-atrial-fibrillation-after-coronary-artery-bypass-graft-100575149","NCT06768528","Association Between GalectiN-3 and POSt-operative AtrIal Fibrillation After Coronary Artery BypaSs Graft","Association Between Galectin-3 and Post-operative AtrIal Fibrillation After Coronary Artery Bypass Graft","GNOSIS","Inclusion Criteria:\n\n* Patients undergoing coronary artery bypass graft surgery\n\nExclusion Criteria:\n\n* Inability to sign the free and informed consent form\n* Renal dysfunction with estimated glomerular filtration rate less than 30ml \u002F min \u002F 1.73m² or dialysis therapy\n* Moderate to severe left ventricular dysfunction (ejection fraction \\\u003C 40%)\n* Patients with previous atrial fibrillation\n* Pregnancy\n* Concomitant valve surgery",{"count":111,"type":21},90,"The goal of this observational study is to test the association between high levels of Galectin-3 and the occurrence of post-operative atrial fibrillation after isolated coronary artery bypass grafting (CABG). The main question\\[s\\] it aims to answer are:\n\n* Is Galectin-3 an accurate biomarker to predict higher risk of developing post-operative atrial fibrillation?\n* Are high levels of Galectin-3 associated to other post-operative complications and major adverse cardiovascular events? Participants will be enrolled during pre-operative evaluation and a peripheral blood sample collection will be performed in the 24h before CABG. Participants will then be followed for a period of 12 months (daily during hospitalization and 3 appointments after hospital discharge) to determine whether patients with higher levels of Galectin-3 will have worse outcomes.",[88,114,115],"Cardiovascular Diseases","Post-pericardiotomy Syndrome",[117,118],"Post-operative atrial fibrillation","Galectin-3","2025-01-06",{"date":121,"type":36},"2025-01-10",{"date":123,"type":36},"2023-01-01",{"date":125,"type":21},"2026-12-01",{"name":127,"class":73},"University of Sao Paulo General Hospital",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":16,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":135,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":137,"conditions":138,"keywords":139,"overallStatus":142,"whyStopped":4,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":147,"leadSponsor":149,"locationsCount":74},"100574733","post-operative-atrial-fibrillation-post-cardiac-surgery--cabg-and-valve-replacement--100574733","NCT06763120","Post Operative Atrial Fibrillation Post Cardiac Surgery ( CABG and VALVE REPLACEMENT )","Prevelance and Risk Predictors of Post-operative Atrial Fibrillation Among Patients Undergoing Cardiac Surgery At Assiut University Heart Hospital","Inclusion Criteria:\n\n1. ≥18 years scheduled for first-time planned cardiac surgery ( CABG and Valve replacement)\n2. Patients who are in sinus rhythm and not taking any antiarrhythmic medication, other than beta-adrenergic blocking agents, at the time of surgery.\n3. Willingness to participate and provision of informed consent\n\nExclusion Criteria:\n\n1. Prior history of cardiac surgery.\n2. Pediatric population less than 18 years.\n3. Patients with history of hyperthyroidism\n4. Patients with electrolyte disturbance\n5. Where follow-up is not possible.\n6. The patient refused to sign the informed consent to participate in the research.",{"count":136,"type":21},112,"This study aims to assess the percent and risk factors of postoperative atrial fibrillation in patients undergoing cardiac surgery in Assiut university heart hospital",[27],[140,141],"Post operative atrial fibrillation","Cardiac surgery","NOT_YET_RECRUITING","2025-01-01",{"date":145,"type":36},"2025-01-08",{"date":143,"type":21},{"date":148,"type":21},"2026-08-30",{"name":150,"class":73},"Assiut University"]