[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-operative-sensitivity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-operative-sensitivity":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100607406","phase-2-gluma-compared-with-bonding-agent-for-post-operative-sensitivity-following-composite-restorations-100607406",false,"NCT07188142","Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations","Investigating the Effects of Two Different Desensitizing Agents on Mitigating Post-Operative Sensitivity Following Composite Restorations - a Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18-45 years.\n* Good oral hygiene.\n* Active primary class I carious lesions on vital molar teeth with ICDAS score 3\n* Patients complaining of sensitivity to air and osmotic stimulus.\n* Teeth having a positive cold test.\n* No signs of pulp inflammation or spontaneous pain before treatment.\n\nExclusion Criteria:\n\n* Excessive tooth wear due to clenching or abnormal habits.\n* Traumatic occlusion.\n* Periodontal or gingival disease.\n* Patients using analgesics and\u002For anti-inflammatory medicine.","ALL","18 Years","45 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24,25],"PHASE2","PHASE3","* The aim of this study is to compare the effectiveness of Gluma desensitizer in reducing post-operative sensitivity following composite restorations in posterior teeth. -Patients visiting OPD will be selected after fulfilment of inclusion criteria. Patients aged 18-45 meeting inclusion criteria and presenting with active primary class I carious lesions on vital molar teeth with ICDAS score 3 will be randomly assigned into two groups: -Group A: Patients will be provided with Gluma desensitizer, Universal Bonding agent and Composite restoration and -Group B: Patients will receive Universal bonding agent and Composite restoration. -The progress of treatment will be followed up immediately (baseline) and at regular follow up visits at 1 week, 1 month and 3 months.\n* Post-operative sensitivity will be assessed using an air stimulus and rated on a numeric rating scale for post-operative sensitivity assessment ranging from 0 to 10.",[28,29,30,31,32],"Post-operative Sensitivity","Dentin Hypersensitivity","Dental Caries","Tooth Sensitivity After Composite Restorations","Post-operative Sensitivity After Class I Composite Restorations",[34,35,36,37,38],"Post-operative sensitivity","Dentinal hypersensitivity","Class I caries","Gluma desensitizer","Composite restoration","NOT_YET_RECRUITING","2025-09-19",{"date":42,"type":43},"2025-09-23","ACTUAL",{"date":45,"type":21},"2025-12-01",{"date":47,"type":21},"2026-06-01",{"name":49,"class":50},"Beenish Hassan","OTHER"]