[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-operative-surgical-site-infection\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-operative-surgical-site-infection":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100414556","phase-3-evaluation-of-a-new-strategy-for-protocolized-antibiotic-care-for-severe-open-fractures-sextant-100414556",false,"NCT04678154","Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT","Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT - A Multicenter Randomized Control Trial","Inclusion Criteria:\n\n1. Injury meeting at least one of the following criteria:\n\n   * Gustilo type III tibia (OTA 41 plateau, OTA 42 shaft and OTA 43 pilon) requiring a second procedure for final debridement and definitive coverage \u002F closure following the index stabilization\n   * Gustilo type IIIB ankle fractures (OTA 44)\n   * Gustilo type IIIB calcaneus fractures (OTA 82)\n   * Gustilo type IIIB talus fractures (OTA 81)\n   * Traumatic \"zone-of-injury\" trans-tibial amputations requiring DPC, and\u002For flap coverage\n2. Ages 18 - 64 years inclusive\n3. Patients may have risk factors for infection including diabetes, immunosuppression from steroids or other medications, HIV, or other infections.\n4. Patients may have a traumatic brain injury.\n5. Patients may have other fractures including spine, upper extremity fractures, contralateral lower extremity injuries, ipsilateral pelvis, hip, femur or foot injuries.\n6. Patients may be treated initially at an outside institution prior to transfer to the study institution, as long as the definitive wound closure or coverage was not performed prior to entrance into the study.\n7. Patients with bilateral injuries that meet inclusion criteria may be included, but only the limb rated as \"more severe\" by the treating surgeon will be enrolled in the study.\n8. Patients may have co-existing non-tibial or hindfoot infection, with or without antibiotic treatment.\n9. Patients may be definitively stabilized using any method (nail, plate, ex fix or cast).\n10. Patients may have a fasciotomy.\n\nExclusion Criteria:\n\n1. Patient in current therapy for a wound, implant or fracture site infection related to the study site.\n2. Patient likely to have difficulty maintaining follow-up, including:\n\n   * Diagnosis of a severe psychiatric condition\n   * Intellectually challenged without adequate family support\n   * Resides outside of the hospital's catchment area\n   * Planning to follow-up at another medical center\n   * Being a prisoner\n   * Not having a means of contact (address, cell phone, home phone, e-mail)","ALL","18 Years","64 Years",{"count":20,"type":21},1200,"ESTIMATED","INTERVENTIONAL",[24],"PHASE3","The proposed study is a multi-center, prospective randomized controlled trial comparing current standard of care treatment to the SEXTANT treatment protocol in patients with Type III open fractures of the tibia and IIIB fractures of the ankle and hindfoot.",[27],"Post Operative Surgical Site Infection",[29,30],"Surgical site infection risk prevention","Bacterial species type and antibacterial sensitivities","RECRUITING","2026-05-21",{"date":34,"type":35},"2026-05-26","ACTUAL",{"date":37,"type":35},"2021-05-07",{"date":39,"type":21},"2027-03-31",{"name":41,"class":42},"Major Extremity Trauma Research Consortium","OTHER",31,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":57,"conditions":58,"keywords":69,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":5},"100562499","prevention-of-edema-after-coronary-artery-bypass-graft-by-customized-pressure-guided-elastic-bandages-100562499","NCT06603961","Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages","Efficacy of Customized Pressure-Guided Elastic Bandages in Preventing Postoperative Edema and Complications in Coronary Artery Bypass Graft (CABG) Patients: A Comparative Study of Compression Therapy and Standard Post-CABG Care.","PEACCE","Inclusion Criteria:\n\n1. All patients scheduled for elective coronary artery bypass grafting (CABG) surgery with saphenous vein harvesting from the leg at Siriraj Hospital.\n2. Patients aged 18 years and older undergoing CABG surgery with saphenous vein harvesting from the leg at Siriraj Hospital, who willingly consent to participate in the study.\n\nExclusion Criteria:\n\n1. Patients with an Ankle-brachial pressure index (ABI) \\\u003C 0.8\n2. Patients with severe leg swelling (pitting edema of grade 3 or higher) or with pre-existing or post-operative heart failure that remains uncontrolled despite diuretic therapy.\n3. Patients with occlusive peripheral arterial disease (PAD) or chronic venous insufficiency (CEAP 2s), characterized by significant venous stasis, leg pain, varicose veins, or lymphadenopathy.",true,{"count":54,"type":21},106,[56],"NA","The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients. While compression therapy, like compressive stockings, has benefits in preventing edema, concerns about affordability persist. CPG-EB provides optimal sub-bandage pressure, proven effective in venous leg ulcers. Implementing CPG-EB post-CABG could enhance venous blood flow, reducing complications and improving outcomes. Patients were divided into two groups: one with CPG-EB and the other standard post-CABG care. Data collected at 1, 2, and 6 weeks post-surgery assessed swelling and wound complications. Comparative analysis used standardized criteria.",[59,60,61,62,63,64,65,66,67,68,27],"Limb Edema","Surgical Site Infections","Leg Swelling","Compression Bandages","Coronary Artery Bypass Graft","CABG","Saphenectomy","Saphenous Vein","Delayed Wound Healing","Post Operative Complications",[70,71,72,64,73],"compression bandages","compression therapy","customized pressure-guided elastic bandages","coronary arterial bypass graft","2026-02-06",{"date":76,"type":35},"2026-02-09",{"date":78,"type":35},"2025-01-19",{"date":80,"type":21},"2026-05-31",{"name":82,"class":42},"Siriraj Hospital"]