[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-spinal-hypotension\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-spinal-hypotension":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100592612","ketamine-for-preventing-post-spinal-hypotension-in-orthopedic-surgery-100592612",false,"NCT06995690","Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery","Impact of Sub-anesthetic Dose of Ketamine in the Prevention of Post Spinal Hypotension in Patients Undergoing Orthopedic Surgeries","Inclusion Criteria:\n\n* Patients American Society of Anesthesiologists Physical Status (ASA) I to II undergoing orthopedic surgeries under spinal anesthesia.\n* Both Sexes.\n* Patients aged equal to or above 18 years.\n* Body mass index \\\u003C35 kg\u002Fm2\n* Duration of operation from 1 hour to 3 hours\n\nExclusion Criteria:\n\n* Patients' refusal of procedure or participation in the study.\n* Patients with contraindication to spinal anesthesia.\n* Patients with cardiovascular or pulmonary disease.\n* Patients with pre-procedural hypotension (systolic arterial pressure less than 90 mmHg and\u002For mean arterial pressure less than 60 mmHg).\n* Patients aged below 18 years.\n* Duration of operation below 1 hour or above 3 hours.","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg\u002Fkg IV) in preventing post-spinal hypotension in patients undergoing elective orthopedic surgeries under spinal anesthesia. The study compares ketamine with placebo (normal saline) in terms of blood pressure stability and incidence of hypotensive episodes following spinal anesthesia.",[26,27,28],"Post-spinal Hypotension","Orthopedic Surgery","Spinal Aneshtesia",[30,31,32,33,34,35,36,37,38,39],"Ketamine","Sub-anesthetic dose","Hypotension prevention","Neuraxial anesthesia","Hemodynamic stability","regional anesthesia","ASA I-II","Double-blind randomized trial","Blood pressure monitoring","Ephedrine use","RECRUITING","2025-06-15",{"date":43,"type":44},"2025-06-18","ACTUAL",{"date":46,"type":44},"2025-06-01",{"date":48,"type":20},"2025-11-01",{"name":50,"class":51},"Ain Shams University","OTHER"]