[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-stroke\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-stroke":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,56,83,114,154,183,213,239,265,298],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100639065","evaluation-of-the-impact-of-virtual-park-on-training-motivation-in-adult-patients-100639065",false,"NCT07616050","Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients","Evaluation of the Impact of a Rehabilitation Intervention Based on Cycling With Virtual Park on Training Motivation in Adult Patients","VP_Adults","Inclusion Criteria:\n\n* Informed consent to the study\n* subjects \\> 18 years and \\\u003C85 years\n* diagnosis of MCI according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders VTh Edition (DSM V TR American Psychological Association 2013)\n* detection of ischemic stroke within 6 months preceding the study, frail elderly subjects (Gobbens RJ et al. 2010)\n* subjects affected by idiopathic Parkinson's disease according to the MDS-PD criteria (Postuma et al., 2015)\n* subjects affected by possible, probable and definite ALS according to the revised El Escorial criteria (Brooks Br, et al. 2000)\n* subjects affected by MS according to the McDonald criteria (2017) with disability measured with the EDSS (Expanded Disability Status Scale) \\\u003C= 8\n* patients with spinal cord injury of different etiology with incomplete spinal cord injury, AIS (ASIA impairment scale) grade C and D, MMSE \\>18\n* subjects naïve to the use of the RV\n* no therapeutic changes or rehabilitation interventions in the month prior to inclusion in the study\n* no ongoing behavioral disorders.\n\nExclusion Criteria:\n\n* Other concomitant neurological pathologies in addition to the one under study\n* presence of visual disturbances that do not allow access to the experimental virtual reality protocol\n* presence of impaired cardiorespiratory function or other organic instabilities that contraindicate ergometer training\n* severe osteoporosis","ALL","18 Years",{"count":20,"type":21},70,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this clinical study is to evaluate the feasibility, usability, and motivational impact of VirtualPark, a virtual reality-based dual-task rehabilitation system, in adults with neurological and age-related conditions.\n\nVirtualPark is a virtual reality application designed to deliver cognitive exercises during cycling training using a commercially available ergometer (THERA-Trainer Tigo). The system integrates physical and cognitive tasks in simulated real-life environments.\n\nThe intervention integrates motor and cognitive training tasks targeting domains such as attention, inhibition, working memory, and navigation.\n\nThis is a prospective, multicenter, randomized, cross-over pilot study. It will compare cycling training performed with and without virtual reality. Participants will complete both intervention conditions over a 4-week period separated by a wash-out phase with standard rehabilitation activities. The order of conditions will be randomized.\n\nThe study will assess motivation during rehabilitation training, usability and user experience of the system, as well as exploratory effects on cognitive and motor performance, functional abilities, perceived exertion, and safety.\n\nThe study will enroll adult participants (≥18 years) with conditions such as stroke, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, mild cognitive impairment, spinal cord injury, and frail older adults.",[27,28,29,30,31,32],"Post-stroke","Parkinson Disease","Amyotrophic Lateral Sclerosis","Mild Cognitive Impairment (MCI)","Multiple Sclerosis","Frailty at Older Adults",[34,35,29,36,31,37,38,39,40,41,42],"post-stroke","parkinson disease","Mild Cognitive Impairment","spinal cord injury","rehabilitation","dual-task","virtual reality","intrinsic motivation","frail elderly patients with multiple comorbidities","NOT_YET_RECRUITING","2026-05-25",{"date":46,"type":47},"2026-05-29","ACTUAL",{"date":49,"type":21},"2026-06",{"date":51,"type":21},"2027-01",{"name":53,"class":54},"Marta Mondellini","OTHER",7,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":65,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":82},"100624237","pori-clinical-trial-100624237","NCT07407023","PoRI Clinical Trial","Randomized Clinical Trial of (PoRI) Post-Stroke Hand Rehabilitation Device","Inclusion Criteria:\n\n* Between 2 days and a maximum of 2 months have passed since the stroke event\n* 0-3\u002F5 muscle strength\n* Participants with paralysis or sensorimotor function problems of the fingers of one or both hands.\n* Participants must be able to fit their hand comfortably into the device.\n\nExclusion Criteria:\n\n* Less than 2 days or greater than 2 months have passed since the stroke event\n* 4-5\u002F5 muscle strength\n* Vulnerable populations.\n* Inability of fingers and wrist to stretch to neutral during passive range of motion",{"count":64,"type":21},12,[24],"This randomized clinical trial compares the Portable Rehabilitation Interface (PoRI) device for rehabilitation of hand motor function in post-stroke patients with conventional hand therapy.",[68,69],"Post Stroke","Post Stroke Hand Rehabilitation",[71],"sensorimotor hand dysfunction","RECRUITING","2026-03-24",{"date":75,"type":47},"2026-03-27",{"date":77,"type":47},"2026-03-23",{"date":79,"type":21},"2027-09",{"name":81,"class":54},"Yale University",1,{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":22,"phases":93,"briefSummary":94,"conditions":95,"keywords":98,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":82},"100626174","therapeutic-music-listening-in-post-stroke-patients-100626174","NCT07432204","Therapeutic Music Listening in Post Stroke Patients.","Therapeutic Music Listening in Post Stroke Patients: a Multicenter Randomized Controlled Trial.","ML4STROKE","Inclusion Criteria:\n\n* Diagnosis of first ischemic or hemorrhagic stroke verified by Computerized Axial Tomography or Magnetic Resonance\n* Age above 18 years\n* Mini Mental State Examination ≥ 24\n* Latency from the event \\\u003C 3 months\n* Presence of clinically significant anxiety and\u002For depression (Generalized Anxiety Disorder and\u002For Patient Health Questionnaire ≥10)\n* Onset of acute event not more than 90 days prior to enrollment in the study\n\nExclusion Criteria:\n\n* Clinical instability\n* Lesions dated over 3 months from onset\n* Multiple or bilateral lesions\n* Mini Mental State Examination \\\u003C 24\n* Previous or concomitant neurological, psychiatric, or internal pathologies found in the year preceding the study that, in the judgment of the clinical investigator, may affect the psychological condition and\u002For interfere with study procedures\n* Behavioral\u002Fcognitive disorders that prevent adequate patient compliance with treatment\n* Therapeutic-rehabilitative treatments with music in the year preceding the study\n* Previous musical skills (training or musical practice lasting more than 3 years)\n* Refusal or impossibility to sign informed consent\n\nFor the subgroup of patients subjected to functional Magnetic Resonance, the following exclusion criteria will also be taken into account:\n\n* Incompatibility with the execution of the MRI investigation (e.g., ascertained or possible presence of metal in the body; claustrophobia; sickle cell anemia)\n* Inability to understand or provide informed consent for the execution of the MRI investigation",{"count":92,"type":21},132,[24],"Numerous studies have highlighted how individualized music listening favors motor, cognitive, and emotional recovery in post-stroke patients, stimulating neuroplasticity and cerebral connectivity. However, gaps persist regarding the standardization of protocols and the neural mechanisms involved. This study aims to bridge these gaps with a rigorous scientific approach, integrating clinical assessments and neuroimaging.\n\nThis is a multicenter randomized controlled single-blind trial. Subjects will be allocated into 2 groups: an experimental group subjected to a 4-week intervention of daily Therapeutic Music Listening sessions (Raglio, 2023) in addition to conventional therapeutic interventions (standard care), and a control group subjected solely to conventional therapeutic interventions (standard care). A follow-up is scheduled for one month after the conclusion of treatment. The study duration is 24 months and the screening phase will be continuous until the conclusion of planned recruitment.\n\nPrimary objective of the study is to evaluate the efficacy of Therapeutic Music Listening (TML) on anxiety in post-stroke patients.\n\nSecondary objective of the study is to investigate other possible effects on depression, quality of life, cognitive aspects (specifically attention and memory), and on connectivity via functional Magnetic Resonance Imaging (fMRI).\n\nPrimary endpoint is the reduction of anxiety. Secondary endpoint is the improvement in depression, quality of life, cognitive functions, and cerebral connectivity parameters.",[68,96,97],"Anxiety","Depression",[99,100,96,97,101,102,103,104],"Therapeutic Music Listening","Stroke","Neuroplasticity","fMRI","Cognitive functions","Connectivity","2026-02-18",{"date":107,"type":47},"2026-02-25",{"date":109,"type":47},"2025-11-12",{"date":111,"type":21},"2027-12-31",{"name":113,"class":54},"Istituti Clinici Scientifici Maugeri SpA",{"id":115,"slug":116,"hasResults":11,"nctId":117,"briefTitle":118,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":124,"phases":4,"briefSummary":125,"conditions":126,"keywords":133,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":153},"100625942","impact-study-on-users-of-upper-limb-assistive-devices-100625942","NCT07429188","Impact Study on Users of Upper Limb Assistive Devices","Impact Study on Users of Upper Limb Assistive Devices (AMUSE)","AMUSE","Inclusion Criteria:\n\nFOR PATIENT-USER :\n\n* Age ≥ 18 years\n* Effective use of a CE-marked upper-limb assistance device for at least 60 days\n* Access to a computer with an internet connection and ability to participate in a videoconference\n* Having provided free and informed non-opposition, or, where applicable, their legal representative\n* Cognitive abilities compatible with completing the questionnaires and interviews\n* Medically stable (no ongoing medical event likely to affect the proper conduct of the study)\n\nFOR CAREGIVER-USERS (RELATIVES AND\u002FOR PROFESSIONALS) :\n\n* Age ≥ 18 years\n* Relatives or professionals living with or regularly interacting with the patient-user of an upper-limb assistance device\n* Access to a computer with an internet connection and ability to participate in a videoconference\n* Having provided free and informed non-opposition\n\nExclusion Criteria:\n\nFOR PATIENT-USER :\n\n* Participant enrolled in another protocol evaluating a technical aid\n* Insufficient mastery of the French language\n\nFOR CAREGIVER-USERS (RELATIVES AND\u002FOR PROFESSIONALS)\n\n* Insufficient mastery of the French language\n* Cognitive impairments preventing understanding of the questions",{"count":123,"type":21},150,"OBSERVATIONAL","This impact study of upper limb (UL) assistance devices is part of the Exploratory PEPR O2R \"Robotic assistance for human movements.\" The integrated project PI3 \"ASSISTMOV,\" composed of a multidisciplinary team in engineering and Human and Social Sciences (HSS), targets the use case of employing robotic assistance for the movement of persons with disabilities (PWD). Through the development of a range of exoskeletons (lower and upper limbs), this project aims for a breakthrough technology enabling fluid and robust interaction with a variety of environments and uses (from rehabilitation to daily life).\n\nThe proposed study contributes to this objective by exploring the clinical and psychosocial dimensions of the daily use of UL assistance devices. Through interviews and questionnaires, it aims to collect data on their impact in terms of independence in activities of daily living (ADL), satisfaction, quality of life, social participation, as well as social perceptions related to the use of these technical aids. It will make it possible to document the benefits and limitations of existing devices from the users' point of view (patients and informal and\u002For professional caregivers), by identifying the factors that facilitate or hinder their adoption and by exploring the care pathway, from prescription to daily use. The questionnaires will also allow examination of economic dimensions.\n\nThe participants included in this study will be recruited among users already using, in their daily life, an UL movement assistance device. All will be regular users of their device, functionally integrated into their usual environment for at least two months. Only devices benefiting from CE marking, guaranteeing their compliance with European regulations, will be eligible. No equipment will be specifically provided within the framework of this research: each participant will share their experience with their own device, as it is integrated into their ADL. A preliminary literature review helped identify the main categories of UL movement assistance devices, grouped according to the following typologies: grasping gloves, mealtime aids, robotic manipulation arms, and arm supports (electric or mechanical).\n\nThe purpose of the approach is both diagnostic and forward-looking. It is diagnostic in that it makes it possible to analyze current practices, real activity, and users' viewpoints, in order to identify elements likely to be improved in the recommendation and use of the devices. It is also forward-looking, since it aims to identify new opportunities, needs, or potential developments, in order to support the thinking of roboticists based on field observations.",[127,128,27,129,130,131,132],"User of an Upper Limb Assistance Device","User Experience","Spinal Cord Injury","Neuromuscular Disorders","Arthrogryposis","Motor Impairment",[134,135,136,137,138,139,140,141,142,143],"Family caregiver","upper limb assistance device","user","professional caregiver","CE-marked assistive device","mechanical arm supports","electric arm supports","robotic arms","grasping gloves","mealtime aids","2026-02-17",{"date":146,"type":47},"2026-02-24",{"date":148,"type":47},"2026-02-12",{"date":150,"type":21},"2027-05",{"name":152,"class":54},"Association APPROCHE",2,{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":4,"eligibilityCriteria":160,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":161,"targetDuration":4,"studyType":22,"phases":162,"briefSummary":163,"conditions":164,"keywords":169,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":174,"lastUpdatePostDateStruct":175,"startDateStruct":177,"completionDateStruct":179,"leadSponsor":181,"locationsCount":4},"100619335","nursing-health-education-to-improve-functionality-and-quality-of-life-after-ischemic-stroke-100619335","NCT07343284","Nursing Health Education to Improve Functionality and Quality of Life After Ischemic Stroke","Effect of a Nursing Intervention Based on Health Education on Functionality, Depression Symptoms, and Quality of Life in Patients With Ischemic Stroke: A Quasi-Experimental, Longitudinal, and Prospective Clinical Trial","Inclusion Criteria:\n\n* Anterior or posterior cerebral occlusion\n\nExclusion Criteria:\n\n* Intracranial hemorrhage\n* Pregnancy\n* Cognitive incapacity for participation\n* Refusal to participate in the study and administer the questionnaires.",{"count":20,"type":21},[24],"This study is titled \"Effect of a Nursing Intervention Based on Health Education on Functionality, Depression Symptoms, and Quality of Life in Patients with Ischemic Stroke.\" It is a quasi-experimental, longitudinal, prospective clinical trial that will beconducted with patients who have suffered an ischemic stroke and were treated in the neurology unit of the Lucus Augusti University Hospital, the same center where this study will take place.\n\nThe primary objective of the study is to determine the effect of a nursing intervention based on health education on quality of life and depression symptoms in individuals who have experienced an ischemic stroke.\n\nTo achieve this objective, variables such as cognitive status, depression symptoms, autonomy and ability to perform basic activities of daily living, neurological deficits, and quality of life will be assessed.\n\nRegarding the total number of subjects to be studied, according to the Stroke Atlas in Galicia published by the Spanish Society of Neurology in 2018, the autonomous community of Galicia had a population of 2,701,819 inhabitants. Applying an incidence rate of 187.4 cases per 100,000 inhabitants according to the IBERICTUS study, an estimated 5,064 new stroke cases occur each year in Galicia. The province of Lugo had 324,842 inhabitants as of January 1, 2024, according to the INE; therefore, applying the same incidence rate, an estimated 609 new stroke cases occur per year. Considering the proportion of ischemic strokes compared to other types of strokes (80:20), the estimated number of ischemic stroke cases in Lugo would be 487. The representative sample size of stroke patients in the province of Lugo would be 70 patients, with 35 patients receiving the intervention and 35 serving as controls.\n\nIndependent Variables:\n\nSociodemographic: sex, age, event date. Clinical: stroke type, treatment modality (rt-PA or thrombectomy), falls, pain, pressure ulcers, aspiration, pneumonia, dysphagia, vital signs.\n\nHealth education: received vs. not received.\n\nDependent Variables:\n\nCognitive status (MMSE). Depression symptoms (BDI). Autonomy and ADL performance (Barthel Index). Neurological deficits (NIHSS). Quality of life (European Quality of Life Scale).\n\nInstruments Mini-Mental State Examination (MMSE) Beck Depression Inventory (BDI) Barthel Index NIH Stroke Scale (NIHSS) Visual Analogue Scale (VAS) European Quality of Life Scale (EQLS)",[165,166,27,167,168],"Ischemia Stroke","Post-stroke Depression","Quality of Life","Health Education",[170,171,97,172,173],"Ischemic stroke","Nursing","Health education","Quality of life","2026-01-07",{"date":176,"type":47},"2026-01-15",{"date":178,"type":21},"2026-06-01",{"date":180,"type":21},"2027-12-01",{"name":182,"class":54},"University of Santiago de Compostela",{"id":184,"slug":185,"hasResults":11,"nctId":186,"briefTitle":187,"officialTitle":188,"acronym":189,"eligibilityCriteria":190,"healthyVolunteers":11,"sex":17,"minAge":191,"maxAge":192,"enrollmentInfo":193,"targetDuration":4,"studyType":22,"phases":195,"briefSummary":196,"conditions":197,"keywords":198,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":205,"startDateStruct":207,"completionDateStruct":209,"leadSponsor":211,"locationsCount":82},"100598952","xingnao-kaiqiao-acupuncture-vs-electroacupuncture-for-post-stroke-upper-limb-recovery-100598952","NCT07078175","Xingnao Kaiqiao Acupuncture vs Electroacupuncture for Post-Stroke Upper Limb Recovery","Effectiveness of Xingnao Kaiqiao Acupuncture Compared to Electroacupuncture in Improving Upper Limb Function in Early Stroke Rehabilitation: A Randomized Controlled Trial","XNKQ-RCT","Inclusion Criteria:\n\n* Patients aged 40 to 80 years\n* Diagnosed with ischemic or hemorrhagic stroke confirmed by CT or MRI\n* Stroke onset between 1 and 6 months prior to enrollment\n* Moderate to severe upper limb motor impairment (FMA-UE score between 20 and 60)\n* Medically stable and able to attend treatment sessions 3 times per week\n* Capable of understanding the study procedures and providing informed consent\n\nExclusion Criteria:\n\n* History of severe cognitive impairment (MMSE score \\\u003C 20)\n* Comorbidities that affect motor function (e.g., Parkinson's disease, multiple sclerosis)\n* Severe aphasia or communication disorder that prevents assessment\n* Botulinum toxin injection in the upper limb within the past 3 months\n* Pacemaker or other contraindications to electroacupuncture\n* Currently participating in another clinical trial\n* Skin infections or local conditions at acupuncture sites","40 Years","80 Years",{"count":194,"type":21},60,[24],"This is a single-center interventional study conducted at the Ho Chi Minh City Hospital for Orthopedics and Rehabilitation, led by investigators from the University of Medicine and Pharmacy at Ho Chi Minh City. The study aims to evaluate the effectiveness of a specific acupuncture protocol (Xingnao Kaiqiao - Brain Awakening Acupuncture) in improving upper limb motor recovery in post-ischemic stroke patients during the early rehabilitation phase.\n\nData collection has been completed, and the study is currently being registered on ClinicalTrials.gov to ensure research transparency, ethical compliance, and to facilitate future publication. The final results and publication will be updated once the study receives a registration number.",[27],[199,200,201,202,203],"acupuncture","Xingnao Kaiqiao","Stroke Rehabilitation","Motor Recovery","Traditional Medicine","2025-07-28",{"date":206,"type":47},"2025-07-31",{"date":208,"type":47},"2024-11-01",{"date":210,"type":21},"2025-08-01",{"name":212,"class":54},"Dr Nguyen Ngo Le Minh Anh MD, PhD",{"id":214,"slug":215,"hasResults":11,"nctId":216,"briefTitle":217,"officialTitle":218,"acronym":219,"eligibilityCriteria":220,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":221,"targetDuration":4,"studyType":124,"phases":4,"briefSummary":223,"conditions":224,"keywords":225,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":231,"startDateStruct":233,"completionDateStruct":235,"leadSponsor":237,"locationsCount":82},"100591899","perception-of-advanced-rehabilitation-technologies-among-post-stroke-patients-and-rehabilitation-staff-100591899","NCT06986421","Perception of Advanced Rehabilitation Technologies Among Post-Stroke Patients and Rehabilitation Staff","Perception of Post-stroke Patients, Physical and Rehabilitation Medicine Physicians, and Allied Health Professionals Regarding Advanced Rehabilitation Technology","P-TECH-AVC","Inclusion Criteria:\n\n* Patients: Patients diagnosed with stroke, whether or not they have benefited from advanced rehabilitation technologies.\n* Physicians: Physicians specialized in Physical and Rehabilitation Medicine who manage patients with stroke.\n* Allied health professionals: Physiotherapists, psychologists, occupational therapists, speech therapists, neuropsychologists, and psychomotor therapists involved in the rehabilitation of post-stroke patients.\n\nExclusion Criteria:\n\n* Refusal to participate in the study.\n* Patients who do not wish to benefit from advanced rehabilitation technology.\n* Healthcare professionals with no experience using advanced rehabilitation technologies.",{"count":222,"type":21},80,"This observational study aims to assess the perception of advanced rehabilitation technologies among three key groups involved in stroke recovery: post-stroke patients, physicians specialized in Physical and Rehabilitation Medicine, and allied health professionals. The study is conducted at HCL - Renée Sabran Hospital , specifically within the Kermes 2 department. Participants are selected using a non-probability sampling method, based on predefined inclusion and exclusion criteria. Data will be collected using a structured, author-developed questionnaire designed to evaluate attitudes, perceived usefulness, ease of use, and intention to adopt technologies such as exoskeletons, social robots, wearable interactive devices, and biofeedback systems. The questionnaire is applied at a single time point after obtaining informed consent. This research responds to the growing integration of technology in neurorehabilitation and seeks to identify potential barriers or facilitators to its adoption in clinical practice.\n\nThe hypothesis is that there is a significant difference in perception and acceptance of advanced rehabilitation technologies between the three groups, influenced by their respective roles, experience, and level of exposure to such technologies.",[68],[226,100,227,228,229],"Rehabilitation","Advanced Technology","Perception","Questionnaire","2025-07-11",{"date":232,"type":47},"2025-07-16",{"date":234,"type":47},"2025-07-08",{"date":236,"type":21},"2026-07-08",{"name":238,"class":54},"Hospices Civils de Lyon",{"id":240,"slug":241,"hasResults":11,"nctId":242,"briefTitle":243,"officialTitle":244,"acronym":4,"eligibilityCriteria":245,"healthyVolunteers":11,"sex":17,"minAge":191,"maxAge":246,"enrollmentInfo":247,"targetDuration":4,"studyType":22,"phases":249,"briefSummary":250,"conditions":251,"keywords":252,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":82},"100554555","combined-effects-of-sensory-integration-and-vestibular-exercises-on-post-stroke-patients-100554555","NCT06500611","Combined Effects Of Sensory Integration And Vestibular Exercises On Post-Stroke Patients","Combined Effects Of Sensory Integration And Vestibular Exercises On Dizziness, Fall Risk And Quality Of Life In Post-Stroke Patients","Inclusion Criteria:\n\n* Both male and female\n* Age between 40years-65years\n* those who have been diagnosed with vestibular disorders\n* An ability to stand for for 5 minutes without aid measured by 5 times sit to stand test.\n\nExclusion Criteria:\n\n* Have bilateral or unstable vestibular loss\n* Any neurological condition is present\n* Active BPPV is present\n* Any acute orthopaedic condition is present\n* Peripheral neuropathy is present\n* Visual impairment not corrected with glasses.","65 Years",{"count":248,"type":21},38,[24],"The aim of this study is to determine the combined effects of sensory integration and vestibular exercise on dizziness, fall risk and quality of life.",[68],[253,254,255],"sensory integration,","stroke","vestibular rehabilitation","2025-04-07",{"date":258,"type":47},"2025-04-09",{"date":260,"type":47},"2024-07-10",{"date":262,"type":21},"2025-03-30",{"name":264,"class":54},"Riphah International University",{"id":266,"slug":267,"hasResults":11,"nctId":268,"briefTitle":269,"officialTitle":270,"acronym":271,"eligibilityCriteria":272,"healthyVolunteers":273,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":274,"targetDuration":4,"studyType":22,"phases":276,"briefSummary":277,"conditions":278,"keywords":283,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":289,"lastUpdatePostDateStruct":290,"startDateStruct":292,"completionDateStruct":294,"leadSponsor":296,"locationsCount":82},"100578748","efficacy-of-shock-wave-therapy-in-post-stroke-muscle-spasticity-management-100578748","NCT06815328","Efficacy of Shock Wave Therapy in Post-Stroke Muscle Spasticity Management","Efficacy of Shock Wave Therapy in Patients with Muscle Spasticity After a Stroke","SWT-PI","\"Inclusion Criteria\":\n\n* Adults aged 18 years or older.\n* Confirmed diagnosis of stroke (ischemic or hemorrhagic) at least 6 months prior to enrollment.\n* Clinically diagnosed muscle spasticity, measured by the Modified Ashworth Scale (MAS), with a score of 0 to 3.\n* Stable medical condition that permits participation in the intervention.\n* No significant changes in spasticity-related treatment for at least 3 months prior to the study.\n* Ability to provide written informed consent to participate in the study.\n* Ability to attend weekly sessions and follow-up visits as required.\n\n\"Exclusion Criteria\":\n\n* Severe spasticity or contractures unresponsive to prior treatments.\n* Contraindications to Shock Wave Therapy, including:\n* Local infections in the treatment area.\n* Known or suspected malignancy near the treatment site.\n* Severe bleeding disorders or anticoagulation therapy.\n* Pregnancy.\n* Neurological conditions other than stroke that could interfere with study outcomes (e.g., Parkinson's disease, multiple sclerosis).\n* Recent treatments that might interfere with spasticity assessment, including:\n* Injections of botulinum toxin within the past 6 months.\n* Recent surgery or other interventions targeting spasticity.\n* Cognitive impairment or other conditions preventing the participant from following instructions or completing study tasks.\n* Severe cardiovascular, renal, or hepatic disease that might complicate therapy or participation.\n* Inability to commit to follow-up visits or complete the intervention protocol due to logistical, mobility, or health-related issues.",true,{"count":275,"type":21},50,[24],"The goal of this clinical trial is to evaluate the efficacy and safety of shock wave therapy (SWT) in reducing muscle spasticity in patients who have suffered a stroke. The main questions it aims to answer are:\n\nDoes SWT reduce muscle tone and improve joint range of motion in post-stroke patients with spasticity? Does SWT improve the quality of life for these patients? What side effects, if any, occur during or after SWT? Researchers will compare SWT to conventional spasticity treatments to determine its effectiveness and potential advantages.\n\nParticipants will:\n\nUndergo SWT sessions as part of their rehabilitation protocol over a period of 8 weeks.\n\nAttend follow-up visits to assess muscle tone, joint mobility, and overall functional improvement.\n\nComplete quality-of-life questionnaires to measure the therapy's impact on daily living.",[100,279,27,280,281,282],"Spasticity","Muscle Hypertonia","Neurological Disorders","Physiotherapy",[284,285,286,167,287,288],"Shock Wave Therapy","Post-Stroke Spasticity","Non-Invasive Therapy","Neurological physical therapy","Muscle Hypertonia Treatment","2025-03-09",{"date":291,"type":47},"2025-03-12",{"date":293,"type":21},"2025-03-15",{"date":295,"type":21},"2025-04-30",{"name":297,"class":54},"University of Oviedo",{"id":299,"slug":300,"hasResults":11,"nctId":301,"briefTitle":302,"officialTitle":303,"acronym":304,"eligibilityCriteria":305,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":192,"enrollmentInfo":306,"targetDuration":4,"studyType":22,"phases":308,"briefSummary":309,"conditions":310,"keywords":312,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":318,"lastUpdatePostDateStruct":319,"startDateStruct":321,"completionDateStruct":323,"leadSponsor":325,"locationsCount":82},"100523718","effects-of-an-eccentric-muscle-strengthening-protocol-on-force-moment-muscle-activation-and-plantar-flexor-structure-of-patients-with-central-nervous-system-injuries-100523718","NCT06099340","Effects of an Eccentric Muscle Strengthening Protocol on Force Moment, Muscle Activation and Plantar Flexor Structure of Patients With Central Nervous System Injuries.","Effects of an Eccentric Muscle Strengthening Protocol on Force Moment, Muscle Activation and Plantar Flexor Structure in Patients With Central Nervous System Injuries. A Randomized Controlled Trial in Post-stroke Patients and a Pilot Study in Spinal Cord Injured Patients.","RenfExc","Inclusion Criteria:\n\n* Patient aged between 18 and 80 years\n* Patient with stroke\\\u003C 6 months or Patient with spinal cord injury American Spinal Injury Association (ASIA) Impairment Scale C or D (incomplete motor impairment) \\\u003C 6 months (second secondary criterion).\n* Patient hospitalized for primary rehabilitation in the neurological PRM department of Nantes University Hospital.\n* Patient with voluntary motricity rated between 2 and 4 on the MRC (Medical Research Council) scale\n\nExclusion Criteria:\n\nHistory of functional surgery \\\u003C3 months or intramuscular injection into plantar flexors \\\u003C6 months\n\n* Patient with osteoarticular lesions contraindicating rehabilitation\n* Patient unlikely to adhere to protocol (severe cognitive impairment) and\u002For non-compliant\n* Patient with a progressive pathology contraindicating efforts (syrinx, cancer, cardiovascular instability, etc.)\n* Minors, protected adults, adults unable to give consent or pregnant women.",{"count":307,"type":21},90,[24],"Neurological disorders \\[such as Cerebral Vascular Accident (CVA) or Spinal Cord Injury (SCI)\\] are among the most costly health problems to society in industrialized countries. For those affected, they generate severe restrictions in mobility, significantly altering their quality of life.\n\nDeterioration in motor function after stroke or BM is closely linked to the level of force produced at joint level. This is influenced by adaptations (neurological and tissue) inherent to the pathophysiology of the injury, and characterized by the presence of a spastic paresis syndrome.\n\nA great deal of effort is devoted to motor neurorehabilitation (particularly physiotherapy) in the days and weeks following neurological injury. This so-called sub-acute rehabilitation phase is designed to have a positive impact on the patient's motor recovery (to prevent the development of spastic paresis), and to prevent future severe limitations in the long term.\n\nDisorders observed in the chronic phase (partial recovery of strength, severe orthopedic deformities) demonstrate the limits of current therapies. In view of the results obtained in healthy subjects, eccentric training now seems to be one of the most promising physiotherapy methods for recovering muscle strength and countering neurological disorders.\n\nHowever, its use in the sub-acute rehabilitation phase has never been evaluated in post-stroke or post-BM patients, either in terms of its effects on the strength developed in the strengthened muscles, or more locally on the neurological and tissue disorders found in these patients in the context of spastic paresis.\n\nThe aim of this project is to evaluate the effects of an eccentric muscle-strengthening exercise protocol on neurological patients in the sub-acute phase of their neurological impairment. The protocol will be applied to the ankle joint, given its importance for walking and the significant deficits found at this level in neurological populations.We hypothesize that the strengthening protocol will improve muscle strength at the ankle, and generate beneficial adaptations to combat the spastic paresis syndrome (improved muscle activation, increased muscle length, muscle volume, etc.).",[311,27],"Spinal Cord Injured",[313,282,314,315,316,100,317],"Neurological rehabilitation","Eccentric muscle strengthening","Strength","Spastic paresis","Spinal cord injury","2024-08-14",{"date":320,"type":47},"2024-08-16",{"date":322,"type":21},"2024-09",{"date":324,"type":21},"2027-10",{"name":326,"class":54},"Nantes University Hospital"]