[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-surgery-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-surgery-patients":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100631902","early-mobilization-following-elective-spine-surgery-trial-of-in-bed-cycling-100631902",false,"NCT07506720","Early Mobilization Following Elective Spine Surgery: Trial of In-bed Cycling","Early Mobilization Following Elective Spine Surgery: Prospective Randomized Trial of In-bed Cycling on Postoperative Day 1","Inclusion Criteria\n\nMale or female ≥ 18 years old.\n\nPostoperative #0 following elective spinal surgery: decompression with or without fusion, or fusion.\n\nPatient able to walk independently before surgery (does not require assistance from another person and does not use a wheelchair).\n\nPatient admitted directly from the operating room to the ward.\n\nHemodynamically stable:\n\nSystolic blood pressure (SBP): ≥ 90 mmHg and \\\u003C 140 mmHg\n\nOxygen saturation \\> 94%\n\nHeart rate: 50-100 bpm\n\nPatient approved for surgery after preoperative internal medicine evaluation.\n\nPatient alert and conscious.\n\nValid informed consent obtained.\n\nExclusion Criteria\n\nNon-ambulatory preoperatively.\n\nBody Mass Index (BMI) \\> 40 kg\u002Fm².\n\nAcute neurological spinal trauma.\n\nNon-neurological musculoskeletal impairment of the lower limbs (e.g., severe osteoarthritis, hip fracture, amputation) limiting the ability to pedal in bed.\n\nUncontrolled comorbidities preventing surgery or intervention (cardiovascular, respiratory, diabetes).\n\nExpected hospital stay of less than 2 days after surgery.\n\nSurgery-related complications: acute neurological deficit, dural tear, cerebrospinal fluid (CSF) leak, residual spinal instability.\n\nTransfer to intensive care unit or hemodynamic instability.\n\nPersistent hemodynamic instability: SBP \\\u003C 90 mmHg or \\> 200 mmHg, oxygen saturation \\\u003C 88%, heart rate \\\u003C 50 or \\> 100 bpm, temperature \\> 38°C.\n\nCapillary blood glucose outside target values: \\\u003C 4.0 or \\> 7.0 mmol\u002FL fasting or pre-meal, \\\u003C 5.0 and \\> 10.0 mmol\u002FL 2 hours post-meal.\n\nPatient confused, disoriented, or agitated.\n\nPatient already evaluated by physiotherapy for discharge planning or intensive functional rehabilitation.\n\nPatient in isolation.\n\nPatient already discharged.","ALL","18 Years",{"count":19,"type":20},88,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to learn if early mobilization using an in-bed cycling device can reduce the amount of time patients spend in bed after elective spine surgery in adults.\n\nThe main questions it aims to answer are:\n\nDoes in-bed cycling on the day after surgery reduce the amount of time patients spend in bed over the next 24 hours?\n\nDoes in-bed cycling reduce the length of hospital stay and improve participation during physiotherapy assessment?\n\nResearchers will compare patients who receive an in-bed cycling session plus standard postoperative care to patients who receive standard postoperative care alone to see if early in-bed cycling improves mobility and recovery after spine surgery.\n\nParticipants will:\n\nBe randomly assigned to either a standard care group or an in-bed cycling group\n\nWear a fitness tracker to measure activity levels and time spent in bed\n\nReceive standard postoperative care\n\nComplete a 30-minute in-bed cycling session on the day after surgery (intervention group only)\n\nBe monitored for pain and vital signs during the study period\n\nUndergo a physiotherapy assessment to evaluate mobility and participation",[26,27,28],"Spine","Post Surgery Patients","Recovery Method",[30,31,32,33,34],"Spine Surgery","Postoperative Recovery","Early Mobilization","In-Bed Cycling","Kinesiophobia","RECRUITING","2026-06-17",{"date":38,"type":39},"2026-06-22","ACTUAL",{"date":41,"type":39},"2025-08-01",{"date":43,"type":20},"2029-01",{"name":45,"class":46},"Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":58,"conditions":59,"keywords":65,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":5},"100633892","patients-with-pancreatic-tumor-use-of-an-app-to-monitor-progress-in-a-simple-and-intuitive-way-by-periodically-completing-targeted-questionnaires-and-providing-educational-and-informational-content-pancreasplus-100633892","NCT07532590","Patients With Pancreatic Tumor: Use of an App to Monitor Progress in a Simple and Intuitive Way by Periodically Completing Targeted Questionnaires and Providing Educational and Informational Content (PancreasPlus).","A Prospective Study on the Use of an App (PancreasPlus) for Home Monitoring and Proactive Management of Patients With Pancreatic Cancer.","Inclusion Criteria:\n\n* Age ≥18; diagnosis of pancreatic cancer (histological\u002Fcytological)\n* Access to a smartphone or tablet and a data connection; basic digital literacy or a caregiver available,\n* Ability to understand and provide informed consent; understanding of the Italian language.\n\nExclusion Criteria:\n\n* Severe uncompensated cognitive impairment,\n* Social or logistical circumstances that prevent follow-up or access to\u002Fuse of the app,\n* Refusal or withdrawal of consent.",{"count":56,"type":20},185,[23],"Caring for people with pancreatic cancer requires good coordination between hospital care and care at home, with different healthcare professionals working closely together. Patients are also becoming more involved in managing their own care on a daily basis. However, this active involvement can be difficult if there is poor communication with healthcare teams, differences in skills or familiarity with digital tools, or systems that do not support patient participation.\n\nThe PancreasPlus app was developed to support patients and caregivers by providing reliable information, self-monitoring tools, and a communication channel with healthcare professionals. The study aims to assess the feasibility, patient engagement, and perceived quality of routine use of the app. It is hypothesized that its use will improve engagement, perceived quality, reduce anxiety and unplanned hospital visits, without introducing technological or privacy risks. The app supports information and data collection but does not replace clinical decision-making.\n\nObjectives\n\nPrimary objectives:\n\nAssess feasibility and patient engagement through questionnaire completion. Evaluate perceived service quality using the Client Satisfaction Questionnaire (CSQ-8).\n\nSecondary objectives:\n\nMonitor unplanned hospital visits and adherence to chemotherapy. Assess anxiety (HADS-A), nutritional status, and global quality of life (PROMIS Global).\n\nEvaluate usability and acceptability of the app (SUS, UTAUT2 short version).\n\nEndpoints Primary endpoints include questionnaire completion rates and perceived quality (CSQ-8 score). Secondary endpoints include unplanned hospital access, chemotherapy adherence, anxiety levels, nutritional status, quality of life, and app usability\u002Facceptability.\n\nMethods This is a prospective, interventional, multicenter study with consecutive enrollment of eligible patients. Each participant will be followed for 3 months, with most activities conducted remotely via the app.\n\nAt baseline (T0), patients receive study information, provide consent, undergo training, register in the app, and complete initial assessments (clinical, socio-demographic, PROMIS Global, HADS-A). At 12 weeks (W12), follow-up includes all outcome questionnaires and data on unplanned hospital visits.\n\nThe app includes features such as a personal diary (symptoms, weight, BMI, appointments), interactive questionnaires with tailored feedback, and educational content on nutrition, prevention, emotional support, and patient rights.\n\nPopulation Inclusion criteria: adults (≥18 years) with pancreatic cancer, access to a smartphone\u002Ftablet (or caregiver support), ability to consent, and understanding of Italian. Exclusion criteria include severe cognitive impairment, inability to use the app or complete follow-up, or withdrawal of consent.\n\nSample Size and Analysis A total of 185 patients will be enrolled (accounting for 10% dropout), based on an expected 70% engagement rate. Analyses will be conducted on both intention-to-observe and per-protocol populations. Engagement will be analyzed as questionnaire completion rates, while other outcomes will be analyzed using appropriate statistical models (e.g., logistic regression, ANCOVA, descriptive statistics). An interim analysis at 50% enrollment is planned to address potential low engagement.",[60,61,62,63,27,64],"Ductal Adenocarcinoma of Pancreas","Pancreatectomy","Caregiver","Nutritional Evaluation","Pain Management",[66,67],"App","Quality of life","2026-05-06",{"date":70,"type":39},"2026-05-11",{"date":72,"type":39},"2026-02-26",{"date":74,"type":20},"2027-04",{"name":76,"class":46},"Casa di Cura Dott. Pederzoli"]