[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-traumatic-stress-symptoms\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-traumatic-stress-symptoms":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,45,72,138,169,199,223,248,277],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100605316","development-of-a-psychosocial-intervention-to-reduce-post-traumatic-stress-in-young-adult-survivors-of-cancer-100605316",false,"NCT07160933","Development of a Psychosocial Intervention to Reduce Post Traumatic Stress in Young Adult Survivors of Cancer","Adaptation and Refinement of a Psychosocial Intervention to Reduce Post-Traumatic Stress in Young Adult Survivors of Cancer","Inclusion Criteria: To be eligible for this study, participants will be:\n\n* Currently aged between 18 - 39;\n* Currently receiving or having completed treatment for cancer at the Mass General Cancer Institute within the past 5 years;\n* Reporting a score denoting at least mild symptoms of PTSD on the Post-traumatic Stress Checklist 5 (PCL-5);\n* English-speaking;\n* Have access to a device with audio\u002Fvideo capabilities to complete virtual intervention sessions.\n\nExclusion Criteria:\n\n* Unable to provide verbal consent\n* Reporting active symptoms of psychosis that preclude safe participation.","ALL","18 Years","39 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this study is to develop a virtual group intervention to address post-traumatic stress related to cancer in young adult cancer survivors (YACs, aged 18-39). The study team will do this by integrating evidence-guided treatments and expert clinician feedback (N=10) on the content, delivery, and structure of the intervention. Next, the study team will refine this intervention through a pilot trial with a group of YACs (N=80).",[27],"Post-traumatic Stress Symptoms",[29,30,31],"young adult cancer survivors","cancer-related post-traumatic stress","post-traumatic stress","NOT_YET_RECRUITING","2026-03-30",{"date":35,"type":36},"2026-03-31","ACTUAL",{"date":38,"type":21},"2026-04-15",{"date":40,"type":21},"2030-06-30",{"name":42,"class":43},"Zeba Ahmad, Ph.D.","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":17,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":44},"100623903","evaluating-symptom-variations-and-observing-longitudinal-individual-change-effects-in-tf-cbt-100623903","NCT07402681","Evaluating Symptom Variations and Observing Longitudinal Individual Change Effects in TF-CBT","EVOLVE","Participants will be included if:\n\n1. they are between 12 and 18 years of age;\n2. they have been exposed to at least one or more traumatic event(s) according to the DSM-5 A criteria after the age of 3 years and dating back at least 1 months (with regard to the ability of patients to remember the event(s) and to the high spontaneous remissions of PTSS in the first month after a traumatic event);\n3. they exhibit high severity of DSM-5 PTSS as indicated by a total symptom score of ≥25 assessed with the Child and Adolescent Trauma Screen 2 (CATS-2);\n4. a nonoffending adult caregiver is available for the treatment and willing to participate in weekly treatment sessions (the inclusion of a caregiver is integral to the TF-CBT treatment model);\n5. they are willing and able to attend weekly treatment sessions;\n6. if their living circumstances are safe and stable to minimize the risk of re-traumatization during the project;\n7. they and their caregiver have sufficient command of the German language (i.e., to participate in assessment \\[read\\] and treatment\\[converse\\]);\n8. they and their caregivers possess a smartphone.\n9. they and their caregiver provided written informed consent.\n\nParticipants will not be included if:\n\n1. they exhibit acute suicidal behavior or have suicidal ideations requiring immediate hospitalization;\n2. they have a documented developmental disorder (i.e., autism spectrum disorder) or current psychosis based on adolescent- and caregiver-report and clinical assessment;\n3. they exhibit severe substance misuse based on clinical assessment;\n4. take part in concurrent psychotherapy during TF-CBT;\n5. exhibit severe intellectual disability based on clinical assessment.","12 Years",{"count":54,"type":21},21,"OBSERVATIONAL","The goal of this observational study is to learn about the level of change in post-traumatic stress symptoms in adolescents with traumatic experiences over the course of trauma-focused cognitive behavioral therapy for children and adolescents according to Cohen, Manarinno, \\& Deblinger (2017).",[27],[59,60,61],"TF-CBT","post-traumatic stress symptoms","single-case experimental design","RECRUITING","2026-02-04",{"date":65,"type":36},"2026-02-11",{"date":67,"type":21},"2026-02",{"date":69,"type":21},"2027-12",{"name":71,"class":43},"University Children's Hospital, Zurich",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":82,"conditions":83,"keywords":95,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":137},"100587056","effectiveness-implementation-and-cost-of-cognitive-processing-therapy-in-prisons-100587056","NCT06923423","Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons","STRIDES2","Inclusion Criteria:\n\n* 18 years of age or older\n* Able to understand and speak English\n* Able to give informed consent\n* All items listed in \"Inclusion criteria for all participants\"\n* Be currently incarcerated in one of the prisons that have partnered as study sites\n* Have met criteria for a drug use disorder in the year prior to their current incarceration (≥ 2 symptoms on a DSM-5 drug use disorder checklist)\n* Have used drugs in the 30 days prior to their current incarceration\n* Have a history of traumatic event exposure\n* Endorse clinically significant posttraumatic stress symptoms (score ≥ 4 on the Primary Care PTSD Screen for DSM-5; PC-PTSD-5)\n* Expect to be incarcerated for at least long enough to complete CPT-CJ as it is being implemented at the particular site (i.e., anticipated to be \\~3 months, but will depend on dates associated with next available intervention group)\n* Expect to be released from prison within 12 months following the end of treatment (i.e., within \\~15 months of the pre-treatment assessment)\n* Willing to consent to randomization to treatment condition\n\nExclusion criteria for prisoners (additional requirements assessed during pre-treatment assessments or indicated by prison staff; will result in being withdrawn from the study prior to randomization by the PI):\n\n* Unable to provide any locator information for post-release assessments\n* Determined to be releasing sooner than would allow the individual to complete CPT-CJ\n* Determined to have an unavoidable scheduling conflict or facility restriction (e.g., disciplinary, medical) that would prevent participation in CPT-CJ. Of note, if the scheduling conflict or facility restriction is expected to resolve following the next round of randomization at the study site, the participant may be put on \"hold for next round\" status rather than withdrawn unless other exclusionary criteria would be met by that time (e.g., release).",{"count":80,"type":21},640,[24],"Addiction and trauma exposure are common among the 5.5 million people (1 in 47 adults) in the U.S. who are in prison or under supervision. About 85% of people in prison have a substance use disorder or are there for a drug-related crime, and many have experienced serious trauma before being incarcerated. Posttraumatic stress symptoms (PTSS) are often a result of trauma and are linked to more severe drug use, higher rates of relapse, and increased crime. PTSS and substance use disorder (SUD) each raise the chances of new arrests for people who are justice-involved, showing that addressing trauma and addiction could help reduce repeat offenses and the costs of incarceration. However, treatments for PTSS are rarely available in prisons, and there is little research on whether providing therapy for PTSS in prison can lower drug use, PTSS, or crime after release.\n\nThe goal of this clinical trial is to see if trauma-focused group therapy (CPT) provided while in prison, can help people after release from prison. The therapy has been adapted for use in prisons (CPT-CJ) and will be compared to trauma focused therapy delivered via a self-help workbook\n\nThis study will:\n\n* test whether a trauma-focused group therapy (CPT-CJ) can reduce post-incarceration drug and alcohol use, mental health issues, and drug-related crime, compared to trauma-focused self-help,\n* evaluate a strategy called implementation facilitation, which helps support the use of this therapy in prisons, and\n* measure the cost of the therapies and support strategies to help plan for future expansion.\n\nIncarcerated participants (N = 640; 50% female) will be enrolled from \\~10 prisons in \\~5 states, ensuring variability in population and setting characteristics. They will:\n\n* take surveys and answer questions up to 5 times (before starting treatment, right after getting treatment, right before leaving prison, 3 months after leaving prison and 6 months after leaving prison)\n* complete CPT group therapy or self-help therapy\n* provide urine samples 3 months and 6 months after leaving prison\n\nPrison stakeholders (e.g., prison staff, prison leadership, governmental officials; N = \\~15 per site) who will be purposively sampled based on their role in CPT-CJ implementation will also participate in some surveys.",[84,85,86,87,88,89,90,91,92,93,94],"PTSD - Post Traumatic Stress Disorder","PTSD and Alcohol Use Disorder","PTSD and Trauma-related Symptoms","Substance Use Disorder (SUD)","Depression","Mental Health","Trauma","Trauma Exposure","Traumatic Stress Disorder","Traumatic Stress","Post Traumatic Stress Symptoms",[96,97,98,99,100,101,102,103,104,105,106,107,108,90,88,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125,126,127],"Post traumatic Stress Disorder","Post traumatic Stress Symptoms","Substance Use","Substance Use Disorder","Cognitive Processing Therapy","Cognitive Processing Therapy for Criminal Justice Setting","Trauma focused self help","Facilitation","Implementation Facilitation","Implementation","Cost Estimation and Offsets","Drug Use Disorder","Alcohol Use Disorder","Adult","Incarcerated","Prison","Imprisonment","Intervention","Treatment Comparison","Acceptability","Feasibility","Budget Impact","Cost Estimate","Implementation Evaluation","Recidivism","Self Help","Workbook","Criminal Justice","Effectiveness","Evidence Based Intervention","CPT","CPT-CJ","2026-01-20",{"date":130,"type":36},"2026-01-21",{"date":132,"type":36},"2025-07-07",{"date":134,"type":21},"2028-12",{"name":136,"class":43},"University of Arkansas",6,{"id":139,"slug":140,"hasResults":11,"nctId":141,"briefTitle":142,"officialTitle":143,"acronym":144,"eligibilityCriteria":145,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":146,"enrollmentInfo":147,"targetDuration":4,"studyType":22,"phases":149,"briefSummary":150,"conditions":151,"keywords":154,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":44},"100611592","ps-trauma---development-of-trauma-treatment-for-patients-with-co-morbid-psychotic-disorders-and-traumas-100611592","NCT07242586","PS-Trauma - Development of Trauma Treatment for Patients With Co-morbid Psychotic Disorders and Traumas","PS-Trauma: Udvikling af Traumebehandling Til Psykiatriske Patienter Med Psykoselidelse - et Pilotstudie.","PS-Trauma","Inclusion Criteria:\n\n* over 18 years of age Diagnosis within schizophrenia spectrum (ICD10 F2X) PTSD symptoms equivalent to above 31 on the PCL-5 Included in Early intervention services (OPUS) Talks and understands Danish\n\nExclusion Criteria:\n\n* Substance or alcohol abuse interfering with the therapy Indication of sever cognitive impairment Changes in antipsychotic treatment within the last month","35 Years",{"count":148,"type":21},20,[24],"Overview:\n\nPeople with psychotic disorders frequently have a history of traumatic events such as neglect, bullying, or physical and sexual abuse. Many experience significant symptoms of post-traumatic stress, but trauma-focused treatment is rarely offered in standard psychiatric care. This pilot study investigates whether two established trauma therapies can be delivered safely and acceptably to young adults with psychotic disorders receiving care in the OPUS early-intervention program.\n\nObjectives:\n\nThe main aim is to evaluate the feasibility and acceptability of two trauma-focused treatments-Prolonged Exposure (PE) and Eye Movement Desensitization and Reprocessing (EMDR)-in patients with psychotic disorders and post-traumatic stress symptoms. The study is not designed to test treatment efficacy but to determine whether a larger randomized controlled trial is practical.\n\nStudy Design:\n\nThis is a pilot and feasibility study. Twenty OPUS patients with a diagnosis within the schizophrenia spectrum and clinically relevant PTSD symptoms will be randomly assigned to either PE or EMDR. All participants continue their usual OPUS care while attending weekly trauma-focused therapy sessions.\n\nAssessments:\n\nAt baseline and follow-up, participants complete clinical interviews and questionnaires assessing trauma symptoms, psychotic symptoms, functioning, well-being, recovery experiences, and possible negative effects. Instruments include the PCL-5, CAPS-5, Mini-TALE, PANSS-6, PSP, WHO-5, Brief INSPIRE-O, NEQ, and CSQ.\n\nPrimary Feasibility Outcomes:\n\nRecruitment: At least 80% of the planned sample enrolled within 6 months.\n\nRetention: At least 70% completing ≥12 therapy sessions.\n\nAcceptability: Participant satisfaction measured with the Client Satisfaction Questionnaire (CSQ).\n\nEligibility:\n\nInclusion:\n\nAge ≥18\n\nDiagnosis within the schizophrenia spectrum (ICD-10: F20-F29)\n\nPTSD symptom score \\>31 on PCL-5\n\nCurrent OPUS patient\n\nSufficient Danish language skills\n\nExclusion:\n\nSubstance use that prevents participation (e.g., attending sessions intoxicated)\n\nSevere cognitive impairment\n\nRecent changes in antipsychotic medication (within 1 month)\n\nRisks and Safety:\n\nTemporary increases in PTSD symptoms may occur when beginning trauma therapy; this pattern is well documented and typically followed by improvement. Previous studies show no higher risk of serious adverse events among patients with psychosis receiving trauma treatment compared with those who do not. Participants are closely monitored, and the study team works in continuous collaboration with OPUS clinicians. If a participant experiences significant clinical deterioration, the therapy can be paused or stopped, and supportive measures will be provided.\n\nPotential Benefits:\n\nParticipants may experience a reduction in trauma-related symptoms and gain access to a treatment that is not otherwise routinely offered to patients with psychotic disorders. The study may help improve future care for this underserved population.\n\nFunding:\n\nThe study is funded by the Nektar Foundation and conducted at the CORE Research Unit, Mental Health Services Copenhagen.",[152,153,94],"SCHIZOPHRENIA 1 (Disorder)","Schizotypal Disorder",[155,90,156,157,158,159],"First episode psychosis","Schizophrenia","psychotherapy","prolonged exposure","EMDR","2025-12-03",{"date":162,"type":36},"2025-12-10",{"date":164,"type":36},"2025-10-02",{"date":166,"type":21},"2026-06-30",{"name":168,"class":43},"Nikolai Albert",{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":175,"eligibilityCriteria":176,"healthyVolunteers":177,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":178,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":180,"conditions":181,"keywords":185,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":194,"completionDateStruct":196,"leadSponsor":197,"locationsCount":44},"100595537","predictors-and-process-moderators-of-emdr-therapy-for-depressive-symptoms-100595537","NCT07033741","Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms","Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms: Protocol for a Real-world Prospective Observational Study","PROCESS-EMDR","Participants:\n\nTherapist\n\n* Inclusion Criteria:\n* certified members of the Italian Eye Movement Desensitization and Reprocessing (EMDR) Association\n* Exclusion Criteria:\n* inability or unwillingness to comply with study protocols or schedules Patient\n* Inclusion Criteria:\n* age 18 years or older\n* capacity of providing informed consent\n* presenting with clinically significant symptoms in at least one of the following domains: anxiety, depression, post-traumatic stress symptoms, or dissociative symptoms.\n* Exclusion Criteria:\n* history of psychotic symptoms or schizophrenia\n* dementia\n* severe personality disorders\n* a serious, unstable medical condition\n* acute suicidality that needs hospitalization.",true,{"count":179,"type":21},40,"The goal of this clinical trial is to evaluate which factors influence the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy for depressive symptoms in real-world settings in Italy.\n\nThe main questions the study seeks to answer are:\n\n* Which key factors influence EMDR outcomes in terms of mediators, moderators, and predictors of its effectiveness for depressive symptoms?\n* Do lower levels of individual psychological functioning at baseline, including high co-occurrence of personality domains and pathogenic personal beliefs, predict the effects of EMDR in treating depressive symptoms?\n* Are baseline psychological comorbidities (anxiety, dissociation, post-traumatic symptoms, emotional dysregulation, and sleep difficulties) and the quality of the therapeutic alliance related to the effectiveness of EMDR therapy for depressive symptoms? Participants will be both therapists and patients.\n* Eligible therapists must be certified members of the EMDR Italian National Association to ensure adherence to established standards in the practice of EMDR therapy and consistency in therapeutic delivery. Therapists will identify patients from their routine clinical practice who meet the study inclusion criteria and facilitate their enrollment.\n* Eligible patients must meet the following criteria:\n\n  1. Being 18 years of age or older.\n  2. being able to give informed consent.\n  3. presenting clinically significant symptoms in at least one of the following domains: anxiety, depression, dissociative, or post-traumatic stress symptoms.\n\nIndividuals presenting with severe neurological impairment or other severe psychiatric conditions were excluded.\n\nResearchers will combine data from multiple N-of-1 trials (N-of-1 or single-subject clinical trials studies) using a Bayesian multilevel random-effects meta-analysis and meta-regression to generate robust estimates of treatment efficacy.",[182,27,183,184],"Depression, Anxiety","Dissociation","Psychotherapy Research and Outcome Measures",[186,187,188,189,157,190],"Eye Movement Desensitization and Reprocessing","depressive symptoms","predictors","moderators","study protocol","2025-11-24",{"date":193,"type":36},"2025-11-25",{"date":195,"type":36},"2025-01-08",{"date":69,"type":21},{"name":198,"class":43},"University of Turin, Italy",{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":206,"enrollmentInfo":207,"targetDuration":4,"studyType":22,"phases":208,"briefSummary":209,"conditions":210,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":4},"100609695","neurofeedback-and-well-being-among-people-with-co-occurring-obsessive-compulsive-disorder-and-post-traumatic-stress-symptoms-100609695","NCT07217925","Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms","Exploring the Influence of Neurofeedback on the Well-Being of People With Symptoms of Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms","Inclusion Criteria:\n\n1. being a client placed on the clinic waitlist to receive exposure-response prevention for OCD symptoms at the Anxiety and OCD Treatment Center of Ann Arbor, in Ann Arbor, MI.\n2. having self-reported symptoms of OCD;\n3. having post-traumatic stress symptoms as indicated by a score of 3 or higher on the Primary Care PTSD Screen for DSM-5 (PC-PTSD-5) screening measure;\n4. being age 18+.\n5. being a citizen of the United States of America -\n\nExclusion Criteria:\n\n1. a lifetime history of significant untreated mental illness (not currently treated schizophrenia, schizoaffective disorder, bipolar disorder, or substance use disorder) or neurological or pervasive developmental disorder;\n2. a documented history of epilepsy;\n3. lifetime history of any head injury with loss of consciousness;\n4. current exposure domestic or intimate partner violence or otherwise state that their current living conditions are unsafe;\n5. current experiences of psychosis or suicidality within the last six months;\n6. currently taking, or in the past month has taken benzodiazepines, narcotic drugs, or cannabis;\n7. currently pregnant\n8. engagement in self-harming behaviors in the last 3 months that required medical attention;\n9. lack of competence to understand or consent to the study procedures;\n10. lack of fluency in written and spoken English. -","90 Years",{"count":148,"type":21},[24],"The proposed study will collect novel data evaluating the feasibility of a neurofeedback training program delivered to prospective clients with a history of clinically concerning trauma-related mental health symptoms who are on a wait list to receive obsessive compulsive disorder-specific psychotherapy at an outpatient mental health clinic. This study will evaluate the influence of neurofeedback training on participant's overall sense of well-being, and additionally, whether any enhanced well-being is subsequently associated with positive changes in symptoms of obsessive compulsive disorder, post-traumatic stress, dissociation and other trauma-related mental health symptoms, emotional regulation, etc.",[211,212,213,183,94],"Well-Being, Psychological","Mood Disturbance","Emotional Regulation","2025-11-10",{"date":216,"type":36},"2025-11-12",{"date":218,"type":21},"2025-11",{"date":220,"type":21},"2029-01",{"name":222,"class":43},"Wayne State University",{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":229,"eligibilityCriteria":230,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":231,"enrollmentInfo":232,"targetDuration":4,"studyType":22,"phases":234,"briefSummary":235,"conditions":236,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":239,"lastUpdatePostDateStruct":240,"startDateStruct":242,"completionDateStruct":244,"leadSponsor":246,"locationsCount":44},"100595090","a-feasibility-trial-of-eye-movement-desensitization-and-reprocessing-therapy--integrative-treatment-group-protocol-for-ongoing-traumatic-stress-in-road-traffic-accident-survivors-for-reduction-of-post-traumatic-stress-symptoms-100595090","NCT07027930","A Feasibility Trial of Eye Movement Desensitization and Reprocessing Therapy- Integrative Treatment Group Protocol for Ongoing Traumatic Stress In Road Traffic Accident Survivors for Reduction of Post-traumatic Stress Symptoms","A Feasibility Trial of Eye Movement Desensitization and Reprocessing Therapy- Integrative Treatment Group Protocol for Ongoing Traumatic Stress in Road Traffic Accident Survivors for Reduction of Post-Traumatic Stress Symptoms","EMDR-IGTP-OTS","Inclusion Criteria:\n\n* Aged between 18 and 45 years.\n* Experienced a traffic accident 3 months to 10 years prior\n* Willing to participate and able to understand the intervention components.\n\nExclusion Criteria:\n\n* Participants will be excluded from the study if they meet any of the following criteria:\n\n  * Diagnosed with conditions such as schizophrenia or bipolar disorder, which require specialized treatment beyond the scope of this study.\n  * History of severe head injuries resulting in neurological or cognitive deficits.\n  * Participants who have experienced a traffic accident less than 3 months ago, as immediate post-traumatic responses may not have stabilized","45 Years",{"count":233,"type":21},35,[24],"Road traffic accidents (RTAs) are a significant public health concern globally, accounting for a substantial proportion of morbidity and mortality. This study evaluates the feasibility and acceptability of the Eye Movement Desensitization and Reprocessing Integrative Group Treatment Protocol for Ongoing Traumatic Stress (EMDR-IGTP-OTS) in the reduction of posttraumatic stress symptoms, depression, and anxiety, while improving the quality of life in individuals who have experienced traffic accidents. Using a randomized control design, participants aged 18-45 will be assessed at three-time points: pre-treatment, post-treatment, and one-month follow-up. The study employs the DASS-21, UIES-R, and WHOQOL-BREF as evaluation measures. Findings aim to expand evidence on trauma-focused interventions and explore their applicability in culturally diverse, resource-constrained settings.",[94,237,238],"Quality of Life (QOL)","Stress","2025-06-16",{"date":241,"type":36},"2025-06-19",{"date":243,"type":36},"2025-05-01",{"date":245,"type":21},"2025-11-01",{"name":247,"class":43},"University of the Punjab",{"id":249,"slug":250,"hasResults":11,"nctId":251,"briefTitle":252,"officialTitle":253,"acronym":4,"eligibilityCriteria":254,"healthyVolunteers":11,"sex":255,"minAge":4,"maxAge":4,"enrollmentInfo":256,"targetDuration":4,"studyType":22,"phases":258,"briefSummary":259,"conditions":260,"keywords":263,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":268,"lastUpdatePostDateStruct":269,"startDateStruct":271,"completionDateStruct":273,"leadSponsor":275,"locationsCount":44},"100576124","effect-of-motivational-interviewing-on-posttraumatic-stress-symptoms-and-posttraumatic-growth-in-women-with-endometrial-cancer-100576124","NCT06781216","Effect of Motivational Interviewing on Posttraumatic Stress Symptoms and Posttraumatic Growth in Women with Endometrial Cancer","Effect of Motivational Interviewing on Posttraumatic Stress Symptoms and Posttraumatic Growth in Women with Endometrial Cancer: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Must be a native Turkish speaker and have no communication barriers\n* Have been diagnosed with endometrial cancer\n* Not be in the process of active treatment (chemotherapy, radiotherapy, hormone therapy, etc.)\n* Be willing to participate in the study\n* Have digital literacy.\n\nExclusion Criteria:\n\n* Not having mental capacity\u002FHaving a psychotic disorder\n* Being in the process of active treatment (chemotherapy, radiotherapy, hormone therapy, etc.)","FEMALE",{"count":257,"type":21},66,[24],"Cancer is still the second leading cause of death worldwide with approximately 9.6 million deaths per year. Gynecological cancers, which are the most common type of cancer among women, significantly affect the quality of life by disrupting the functions of the reproductive system of women. Endometrial cancer has an important place due to its prevalence in our country and worldwide. Although stress factors related to endometrial cancer may continue after the completion of treatment, this situation has the potential to negatively affect the psychological and physiological health of women. This research is a randomized controlled trial aiming to evaluate the effect of motivational interviewing applied to women who completed endometrial cancer treatment and were followed up in the outpatient clinic on post-traumatic stress symptoms and post-traumatic growth. Simple randomization method will be used in the study. The sample size to be included in the study was determined as 66 participants in total, 33 in the intervention group and 33 in the control group. In the study, the effectiveness of motivational interviewing technique application in women with endometrial cancer will be evaluated based on evidence using Post-Traumatic Stress Disorder Checklist for DSM-5, Post-Traumatic Growth Scale and Ways of Coping Scale. Research data will be collected from women who meet the inclusion criteria at Akdeniz University Hospital Gynecology and Obstetrics Clinic between January 2 and August 31, 2025. The motivational interviews planned to be implemented as an intervention method in the research aim to reduce post-traumatic stress symptoms, develop coping strategies and increase the level of post-traumatic growth in women with endometrial cancer.",[261,94,262],"Endometrium Cancer","Post Traumatic Growth, Psychological",[264,265,266,267],"Endometrium cancer","Motivational interviewing","Post traumatic growth","Post traumatic stress symptoms","2025-01-13",{"date":270,"type":36},"2025-01-17",{"date":272,"type":21},"2025-02-03",{"date":274,"type":21},"2025-12-31",{"name":276,"class":43},"Akdeniz University",{"id":278,"slug":279,"hasResults":11,"nctId":280,"briefTitle":281,"officialTitle":282,"acronym":283,"eligibilityCriteria":284,"healthyVolunteers":177,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":285,"targetDuration":4,"studyType":22,"phases":286,"briefSummary":287,"conditions":288,"keywords":290,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":295,"lastUpdatePostDateStruct":296,"startDateStruct":298,"completionDateStruct":300,"leadSponsor":302,"locationsCount":44},"100568576","nonattachment-training-for-post-traumatic-stress-recovery-100568576","NCT06683027","Nonattachment Training for Post Traumatic Stress Recovery","Nonattachment Training for Post Traumatic Stress Recovery: a Pilot Randomised Controlled Trial","NPTS","Inclusion Criteria:\n\n* Current or recent (within 12 months) diagnosis of PTSD (self-disclosed) OR\n* Participants meeting diagnostic requirements of the ITQ OR\n* Participants meeting diagnostic requirements of the PCL-C\n* Participants willing and able to engage in self-directed course content (self-disclosed)\n* Participants willing and able to engage with contemplative principles and practices (self-disclosed)\n\nExclusion Criteria:\n\n* Non-English-speaking participants OR participants with a primary residence outside the UK\n* Under the age of 18\n* Participants with comorbidities such as drug or alcohol misuse which could prevent successful intervention engagement\n* Participants diagnosed with a psychotic disorder",{"count":20,"type":21},[24],"This pilot study aims to investigate the effectiveness of a novel, co-created intervention based on principles of nonattachment for individuals recovering from Post-Traumatic Stress (PTS).\n\nObjectives include:\n\n1. Determine whether participants undertaking nonattachment-based training have higher levels of nonattachment (as indicated by NAS Scale) after completing program.\n2. Determine whether nonattachment levels are impacted after 3 months\n3. Determine whether PTS symptoms are impacted by training\u002Fintervention",[94,289],"PTSD",[291,292,293,283,294,289],"nonattachment","post traumatic stress","co-creation","nonattachment for post traumatic stress","2024-11-08",{"date":297,"type":36},"2024-11-12",{"date":299,"type":21},"2024-11-18",{"date":301,"type":21},"2025-03-01",{"name":303,"class":43},"University of Derby"]